5CGS
| |
5CGW
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-09 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
|
|
5CHJ
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with cephalothin BATSI (SM23) | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, ACETATE ION, Beta-lactamase, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-10 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.358 Å) | 主引用文献 | Structures of FOX-4 Cephamycinase in Complex with Transition-State Analog Inhibitors. Biomolecules, 10, 2020
|
|
5CGX
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F complexed with cefoxitin | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, SODIUM ION, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-09 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
|
|
5CHM
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with ceftazidime BATSI (LP06) | 分子名称: | ACETATE ION, Beta-lactamase, PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-10 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of FOX-4 Cephamycinase in Complex with Transition-State Analog Inhibitors. Biomolecules, 10, 2020
|
|
5CHU
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with sulfate | 分子名称: | ACETATE ION, Beta-lactamase, SULFATE ION, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-10 | 公開日 | 2016-08-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | CRYSTAL STRUCTURE OF Fox-4 cephamycinase complexed with sulfate To Be Published
|
|
3FKW
| |
7V1Z
| human Serine beta-lactamase-like protein LACTB | 分子名称: | Serine beta-lactamase-like protein LACTB, mitochondrial | 著者 | Zhang, M.H, Yang, M.J. | 登録日 | 2021-08-07 | 公開日 | 2022-02-16 | 最終更新日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB. Structure, 30, 2022
|
|
7V21
| |
7V1Y
| |
7ULW
| |
7U1B
| |
7U1C
| Structure of EstG crystalized with SO4 and Tris | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-lactamase domain-containing protein, SODIUM ION, ... | 著者 | Gabelli, S.B, Chen, Z. | 登録日 | 2022-02-20 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | EstG is a novel esterase required for cell envelope integrity in Caulobacter. Curr.Biol., 33, 2023
|
|
7UDA
| Structure of the EstG | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-lactamase domain-containing protein, SODIUM ION | 著者 | Chen, Z, Gabelli, S.B. | 登録日 | 2022-03-18 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | EstG is a novel esterase required for cell envelope integrity in Caulobacter. Curr.Biol., 33, 2023
|
|
3FKV
| AmpC K67R mutant complexed with benzo(b)thiophene-2-boronic acid (bzb) | 分子名称: | BENZO[B]THIOPHENE-2-BORONIC ACID, Beta-lactamase, PHOSPHATE ION, ... | 著者 | Chen, Y, McReynolds, A, Shoichet, B.K. | 登録日 | 2008-12-17 | 公開日 | 2009-03-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.847 Å) | 主引用文献 | Re-examining the role of Lys67 in class C beta-lactamase catalysis. Protein Sci., 18, 2009
|
|
7UL6
| |
5XHR
| Crystal structure of P99 beta-lactamase in complex with a penicillin derivative MPC-1 | 分子名称: | (2~{R},4~{S})-5,5-dimethyl-2-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-5-thiophen-2-yl-pentan-2-yl]-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase | 著者 | Pan, X, Zhao, Y. | 登録日 | 2017-04-24 | 公開日 | 2017-09-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C beta-Lactamases Antimicrob. Agents Chemother., 61, 2017
|
|
5WAC
| ADC-7 in complex with boronic acid transition state inhibitor CR157 | 分子名称: | Beta-lactamase, phosphonooxy-[[[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenyl]sulfonylamino]methyl]borinic acid | 著者 | Powers, R.A, Wallar, B.J. | 登録日 | 2017-06-26 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.061 Å) | 主引用文献 | Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase. ACS Infect Dis, 4, 2018
|
|
5WAG
| ADC-7 in complex with boronic acid transition state inhibitor S06017 | 分子名称: | 1-{[hydroxy(phosphonooxy)boranyl]methyl}-1H-1,2,3-triazole-4-carboxylic acid, Beta-lactamase, SUCCINIC ACID | 著者 | Powers, R.A, Wallar, B.J. | 登録日 | 2017-06-26 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.931 Å) | 主引用文献 | Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase. ACS Infect Dis, 4, 2018
|
|
5WAE
| ADC-7 in complex with boronic acid transition state inhibitor CR167 | 分子名称: | 3-(5,7,7-trihydroxy-2,2,7-trioxo-6-oxa-2lambda~6~-thia-3-aza-7lambda~5~-phospha-5-boraheptan-1-yl)benzoic acid, Beta-lactamase | 著者 | Powers, R.A, Wallar, B.J. | 登録日 | 2017-06-26 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.804 Å) | 主引用文献 | Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase. ACS Infect Dis, 4, 2018
|
|
5WAF
| ADC-7 in complex with boronic acid transition state inhibitor CR192 | 分子名称: | Beta-lactamase, phosphonooxy-[[[4-(1~{H}-1,2,3,4-tetrazol-5-yl)-2-(trifluoromethyl)phenyl]sulfonylamino]methyl]borinic acid | 著者 | Powers, R.A, Wallar, B.J. | 登録日 | 2017-06-26 | 公開日 | 2017-12-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C beta-Lactamase. ACS Infect Dis, 4, 2018
|
|
8CUQ
| X-ray crystal structure of ADC-33 in complex with sulfonamidoboronic acid 6e | 分子名称: | 3-[(4R)-4-ethyl-5,7,7-trihydroxy-2,2,7-trioxo-6-oxa-2lambda~6~-thia-3-aza-7lambda~5~-phospha-5-boraheptan-1-yl]benzoic acid, Beta-lactamase | 著者 | Fernando, M.C, Wallar, B.J, Powers, R.A. | 登録日 | 2022-05-17 | 公開日 | 2023-04-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii . Antibiotics, 12, 2023
|
|
8CUP
| X-ray crystal structure of ADC-33 in complex with sulfonamidoboronic acid 6d | 分子名称: | 3-[(4S)-4-ethyl-5,7,7-trihydroxy-2,2,7-trioxo-6-oxa-2lambda~6~-thia-3-aza-7lambda~5~-phospha-5-boraheptan-1-yl]benzoic acid, Beta-lactamase | 著者 | Fernando, M.C, Wallar, B.J, Powers, R.A. | 登録日 | 2022-05-17 | 公開日 | 2023-04-05 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Sulfonamidoboronic Acids as "Cross-Class" Inhibitors of an Expanded-Spectrum Class C Cephalosporinase, ADC-33, and a Class D Carbapenemase, OXA-24/40: Strategic Compound Design to Combat Resistance in Acinetobacter baumannii . Antibiotics, 12, 2023
|
|
8DC1
| |
8DI7
| CMY-2 | 分子名称: | Beta-lactamase, SULFATE ION | 著者 | Ahmadvand, P, Call, D.R. | 登録日 | 2022-06-28 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural characterization of CMY-2 and its interactions with ampicillin and the cephalosporins - ceftiofur, DFC, DFC-dimer, DFC-cysteine, and nitrocefin To Be Published
|
|