3FKV

AmpC K67R mutant complexed with benzo(b)thiophene-2-boronic acid (bzb)

Summary for 3FKV

Entry DOI	10.2210/pdb3fkv/pdb
Related	1C3B 3FKW
Descriptor	Beta-lactamase, BENZO[B]THIOPHENE-2-BORONIC ACID, PHOSPHATE ION, ... (5 entities in total)
Functional Keywords	ampc, k67r, beta-lactamase, general base, antibiotic resistance, periplasm, hydrolase
Biological source	Escherichia coli
Cellular location	Periplasm: P00811
Total number of polymer chains	2
Total formula weight	79721.98
Authors	Chen, Y.,McReynolds, A.,Shoichet, B.K. (deposition date: 2008-12-17, release date: 2009-03-24, Last modification date: 2023-09-06)
Primary citation	Chen, Y.,McReynolds, A.,Shoichet, B.K. Re-examining the role of Lys67 in class C beta-lactamase catalysis. Protein Sci., 18:662-669, 2009 Cited by PubMed: 19241376 DOI: 10.1002/pro.60 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.847 Å)

Structure validation