PDB: 143 件ウェブページステータス検索Chemie searchBIRD

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6VTV	Crystal structure of PuuD gamma-glutamyl-gamma-aminobutyrate hydrolase from E. coli 分子名称: Gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD, MANGANESE (II) ION 著者 Stogios, P.J, EVDOKIMOVA, E, DI LEO, R, SAVCHENKO, A, JOACHIMIAK, A, SATCHELL, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2020-02-13 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 PuuD gamma-glutamyl-gamma-aminobutyrate hydrolase To Be Published
3R76	Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 in complex with benzoate, pyruvate and glutamine 分子名称: Anthranilate/para-aminobenzoate synthases component I, BENZOIC ACID, MAGNESIUM ION, ... 著者 Li, Q.A, Mavrodi, D.V, Thomashow, L.S, Roessle, M, Blankenfeldt, W. 登録日 2011-03-22 公開日 2011-03-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE. J.Biol.Chem., 286, 2011
3R74	Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 分子名称: Anthranilate/para-aminobenzoate synthases component I 著者 Li, Q.A, Mavrodi, D.V, Thomashow, L.S, Roessle, M, Blankenfeldt, W. 登録日 2011-03-22 公開日 2011-03-30 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE. J.Biol.Chem., 286, 2011
2NV0	Structure of the glutaminase subunit Pdx2 (YaaE) of PLP synthase from Bacillus subtilis 分子名称: Glutamine amidotransferase subunit pdxT 著者 Strohmeier, M, Tews, I, Sinning, I. 登録日 2006-11-10 公開日 2006-12-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structure of a bacterial pyridoxal 5'-phosphate synthase complex Proc.Natl.Acad.Sci.Usa, 103, 2006
3M3P	Crystal structure of glutamine amido transferase from Methylobacillus Flagellatus 分子名称: Glutamine amido transferase 著者 Fedorov, A.A, Domagalski, M, Fedorov, E.V, Burley, S.K, Minor, W, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-03-09 公開日 2010-03-23 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Crystal structure of glutamine amido transferase from Methylobacillus Flagellatus To be Published
2NV2	Structure of the PLP synthase complex Pdx1/2 (YaaD/E) from Bacillus subtilis 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, GLUTAMINE, ... 著者 Strohmeier, M, Tews, I, Sinning, I. 登録日 2006-11-10 公開日 2006-12-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structure of a bacterial pyridoxal 5'-phosphate synthase complex Proc.Natl.Acad.Sci.Usa, 103, 2006
2YWJ	Crystal structure of uncharacterized conserved protein from Methanocaldococcus jannaschii 分子名称: Glutamine amidotransferase subunit pdxT 著者 Manzoku, M, Ebihara, A, Yokoyama, S, Kuramitsu, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-04-20 公開日 2007-10-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of uncharacterized conserved protein from Methanocaldococcus jannaschii to be published
1C30	CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 1999-07-24 公開日 1999-12-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
3R75	Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 in complex with benzoate, pyruvate, glutamine and contaminating Zn2+ 分子名称: Anthranilate/para-aminobenzoate synthases component I, BENZOIC ACID, MAGNESIUM ION, ... 著者 Li, Q.A, Mavrodi, D.V, Thomashow, L.S, Roessle, M, Blankenfeldt, W. 登録日 2011-03-22 公開日 2011-03-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE. J.Biol.Chem., 286, 2011
1C3O	CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 1999-07-28 公開日 1999-12-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
6W2J	CPS1 bound to allosteric inhibitor H3B-374 分子名称: (2-fluoranyl-4-methoxy-phenyl)-[(3~{R},5~{R})-4-(2-fluoranyl-4-methoxy-phenyl)carbonyl-3,5-dimethyl-piperazin-1-yl]methanone, 1,2-ETHANEDIOL, Carbamoyl-phosphate synthase [ammonia], ... 著者 Larsen, N.A, Nguyen, T.V. 登録日 2020-03-05 公開日 2021-01-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Discovery of 2,6-Dimethylpiperazines as Allosteric Inhibitors of CPS1. Acs Med.Chem.Lett., 11, 2020
2AD5	Mechanisms of feedback regulation and drug resistance of CTP synthetases: structure of the E. coli CTPS/CTP complex at 2.8-Angstrom resolution. 分子名称: ADENOSINE-5'-DIPHOSPHATE, CTP synthase, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Endrizzi, J.A, Kim, H, Anderson, P.M, Baldwin, E.P. 登録日 2005-07-19 公開日 2005-11-01 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Mechanisms of Product Feedback Regulation and Drug Resistance in Cytidine Triphosphate Synthetases from the Structure of a CTP-Inhibited Complex(,). Biochemistry, 44, 2005
4WIN	Crystal structure of the GATase domain from Plasmodium falciparum GMP synthetase 分子名称: GMP synthetase, NITRATE ION 著者 Ballut, L, Violot, S, Haser, R, Aghajari, N. 登録日 2014-09-26 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6, 2015
4WIM	Crystal Structure of the GMP Synthetase from Plasmodium falciparum 分子名称: GMP synthetase 著者 Ballut, L, Violot, S, Haser, R, Aghajari, N. 登録日 2014-09-26 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6, 2015
4WXY	PLPS (inactive glutaminase mutant) co-crystallized with glutamine and R5P. 分子名称: Glutamine amidotransferase subunit PdxT, Pyridoxal biosynthesis lyase PdxS 著者 Smith, J.L, Smith, A.M. 登録日 2014-11-14 公開日 2015-01-14 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structures capture three states in the catalytic cycle of a pyridoxal phosphate (PLP) synthase. J.Biol.Chem., 290, 2015
4WIO	Crystal structure of the C89A GMP synthetase inactive mutant from Plasmodium falciparum in complex with glutamine 分子名称: GLUTAMINE, GMP synthetase 著者 Ballut, L, Violot, S, Haser, R, Aghajari, N. 登録日 2014-09-26 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6, 2015
1CS0	Crystal structure of carbamoyl phosphate synthetase complexed at CYS269 in the small subunit with the tetrahedral mimic l-glutamate gamma-semialdehyde 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 1999-08-16 公開日 1999-12-10 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
4L8F	Crystal structure of gamma-glutamyl hydrolase (C108A) complex with MTX 分子名称: Gamma-glutamyl hydrolase, METHOTREXATE 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-17 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L8Y	Crystal structure of gamma-glutamyl hydrolase (C108A) from zebrafish 分子名称: Gamma-glutamyl hydrolase 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-18 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L7Q	Crystal structure of gamma glutamyl hydrolase (wild-type) from zebrafish 分子名称: GLYCEROL, Gamma-glutamyl hydrolase 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-14 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L8W	Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish complex with MTX polyglutamate 分子名称: D-GLUTAMIC ACID, Gamma-glutamyl hydrolase, METHOTREXATE 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-18 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
4L95	Crystal structure of gamma glutamyl hydrolase (H218N) from zebrafish 分子名称: GLYCEROL, Gamma-glutamyl hydrolase 著者 Chuankhayan, P, Kao, T.-T, Chen, C.-J, Fu, T.-F. 登録日 2013-06-18 公開日 2014-05-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Structural insights into the hydrolysis and polymorphism of methotrexate polyglutamate by zebrafish gamma-glutamyl hydrolase J.Med.Chem., 56, 2013
1BXR	STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP 分子名称: CARBAMOYL-PHOSPHATE SYNTHASE, CHLORIDE ION, L-ornithine, ... 著者 Thoden, J.B, Wesenberg, G, Raushel, F.M, Holden, H.M. 登録日 1998-10-08 公開日 1999-04-20 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Carbamoyl phosphate synthetase: closure of the B-domain as a result of nucleotide binding. Biochemistry, 38, 1999
1CE8	CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, INOSINIC ACID, ... 著者 Thoden, J.B, Raushel, F.M, Holden, H.M. 登録日 1999-03-18 公開日 1999-07-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The binding of inosine monophosphate to Escherichia coli carbamoyl phosphate synthetase. J.Biol.Chem., 274, 1999
1GPM	ESCHERICHIA COLI GMP SYNTHETASE COMPLEXED WITH AMP AND PYROPHOSPHATE 分子名称: ADENOSINE MONOPHOSPHATE, CITRIC ACID, GMP SYNTHETASE, ... 著者 Tesmer, J.J.G. 登録日 1995-04-04 公開日 1996-01-29 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The crystal structure of GMP synthetase reveals a novel catalytic triad and is a structural paradigm for two enzyme families. Nat.Struct.Biol., 3, 1996

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