Crystal structure of 2-amino-2-desoxyisochorismate synthase (ADIC) synthase PhzE from Burkholderia lata 383 in complex with benzoate, pyruvate and glutamine

Summary for 3R76

Related3R74 3R75 3R77
DescriptorAnthranilate/para-aminobenzoate synthases component I, MAGNESIUM ION, BENZOIC ACID, ... (6 entities in total)
Functional Keywordsammonia channel, chorismate, type 1 glutamine amidotransferase, phenazine biosynthesis, lyase, synthase, biosynthetic protein
Biological sourceBurkholderia sp.
Total number of polymer chains2
Total molecular weight141243.62
Li, Q.A.,Mavrodi, D.V.,Thomashow, L.S.,Roessle, M.,Blankenfeldt, W. (deposition date: 2011-03-22, release date: 2011-03-30, Last modification date: 2017-11-08)
Primary citation
Li, Q.A.,Mavrodi, D.V.,Thomashow, L.S.,Roessle, M.,Blankenfeldt, W.
Ligand Binding Induces an Ammonia Channel in 2-Amino-2-desoxyisochorismate (ADIC) Synthase PhzE.
J.Biol.Chem., 286:18213-18221, 2011
PubMed: 21454481 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.183418
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22460.3%6.1%2.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-12