4WIN

Crystal structure of the GATase domain from Plasmodium falciparum GMP synthetase

Summary for 4WIN

Entry DOI	10.2210/pdb4win/pdb
Related	4wim 4wio
Descriptor	GMP synthetase, NITRATE ION (3 entities in total)
Functional Keywords	gmp synthetase, plasmodium falciparum, purine salvage pathway, glutamine amidotransferase, transferase
Biological source	Plasmodium falciparum
Total number of polymer chains	2
Total formula weight	57845.42
Authors	Ballut, L.,Violot, S.,Haser, R.,Aghajari, N. (deposition date: 2014-09-26, release date: 2015-12-02, Last modification date: 2024-01-10)
Primary citation	Ballut, L.,Violot, S.,Shivakumaraswamy, S.,Thota, L.P.,Sathya, M.,Kunala, J.,Dijkstra, B.W.,Terreux, R.,Haser, R.,Balaram, H.,Aghajari, N. Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6:8930-8930, 2015 Cited by PubMed: 26592566 DOI: 10.1038/ncomms9930 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation