4WIN
Crystal structure of the GATase domain from Plasmodium falciparum GMP synthetase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003922 | molecular_function | GMP synthase (glutamine-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006177 | biological_process | GMP biosynthetic process |
| B | 0003922 | molecular_function | GMP synthase (glutamine-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006177 | biological_process | GMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue NO3 A 1001 |
| Chain | Residue |
| A | ASN13 |
| A | PHE19 |
| A | THR35 |
| B | ASN13 |
| B | PHE19 |
| B | THR35 |
| B | LYS36 |
| B | ASP37 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue NO3 A 1002 |
| Chain | Residue |
| A | GLN17 |
| A | TYR18 |
| A | GLY57 |
| A | GLY58 |
| A | HIS208 |
| B | TYR60 |
| A | SER16 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue NO3 B 301 |
| Chain | Residue |
| A | TYR60 |
| B | SER16 |
| B | GLN17 |
| B | GLY58 |
| B | HIS208 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile; for GATase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00605","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21413787","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"26592566","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For GATase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00605","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26592566","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4WIO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
