4WIO

Crystal structure of the C89A GMP synthetase inactive mutant from Plasmodium falciparum in complex with glutamine

Summary for 4WIO

Entry DOI	10.2210/pdb4wio/pdb
Related	4WIM 4WIN
Descriptor	GMP synthetase, GLUTAMINE (3 entities in total)
Functional Keywords	gmp synthetase, purine salvage pathway, ligase
Biological source	Plasmodium falciparum
Total number of polymer chains	1
Total formula weight	65458.51
Authors	Ballut, L.,Violot, S.,Haser, R.,Aghajari, N. (deposition date: 2014-09-26, release date: 2015-12-02, Last modification date: 2024-01-10)
Primary citation	Ballut, L.,Violot, S.,Shivakumaraswamy, S.,Thota, L.P.,Sathya, M.,Kunala, J.,Dijkstra, B.W.,Terreux, R.,Haser, R.,Balaram, H.,Aghajari, N. Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun, 6:8930-8930, 2015 Cited by PubMed: 26592566 DOI: 10.1038/ncomms9930 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.15 Å)

Structure validation