4WIO

Crystal structure of the C89A GMP synthetase inactive mutant from Plasmodium falciparum in complex with glutamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	GMP synthetase	polymer	567	65312.4	1	UniProt (Q8IJR9) Pfam (PF00117) Pfam (PF07722) Pfam (PF02540) Pfam (PF00958) In PDB	Plasmodium falciparum
2	A	GLUTAMINE	non-polymer		146.1	1	Chemie (GLN)
3		water	water		18.0	4	Chemie (HOH)

Sequence modifications

A: 2 - 555 (UniProt: Q8IJR9)

PDB	External Database	Details
Met -11	-	initiating methionine
Ala -10	-	expression tag
Ser -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Met 0	-	expression tag
Ala 1	-	expression tag
Ala 89	Cys 89	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	65312.4
Non-Polymers*	Number of molecules	1
	Total formula weight	146.1
All*	Total formula weight	65458.5

*Water molecules are not included.