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4A7U
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Structure of human I113T SOD1 complexed with adrenaline in the p21 space group.
分子名称: ACETATE ION, COPPER (II) ION, L-EPINEPHRINE, ...
著者Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S.
登録日2011-11-14
公開日2012-11-28
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
3F7L
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BU of 3f7l by Molmil
X-ray Crystal Structure of Alvinella pompejana Cu,Zn Superoxide Dismutase
分子名称: ACETIC ACID, COPPER (I) ION, COPPER (II) ION, ...
著者Shin, D.S, DiDonato, M, Barondeau, D.P, Getzoff, E.D, Tainer, J.A.
登録日2008-11-09
公開日2009-02-10
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (0.99 Å)
主引用文献Superoxide Dismutase from the Eukaryotic Thermophile Alvinella pompejana: Structures, Stability, Mechanism, and Insights into Amyotrophic Lateral Sclerosis.
J.Mol.Biol., 385, 2009
4A7V
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BU of 4a7v by Molmil
Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group
分子名称: COPPER (II) ION, L-DOPAMINE, SULFATE ION, ...
著者Wright, G.S.A, Antonyuk, S.V, Kershaw, N.M, Strange, R.W, Hasnain, S.S.
登録日2011-11-14
公開日2012-11-28
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
2WYT
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BU of 2wyt by Molmil
1.0 A resolution structure of L38V SOD1 mutant
分子名称: ACETATE ION, CHLORIDE ION, COPPER (II) ION, ...
著者Antonyuk, S.V, Strange, R.W, Hasnain, S.S.
登録日2009-11-20
公開日2010-10-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural Discovery of Small Molecule Binding Sites in Cu-Zn Human Superoxide Dismutase Familial Amyotrophic Lateral Sclerosis Mutants Provides Insights for Lead Optimization.
J.Med.Chem., 53, 2010
1MFM
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BU of 1mfm by Molmil
MONOMERIC HUMAN SOD MUTANT F50E/G51E/E133Q AT ATOMIC RESOLUTION
分子名称: CADMIUM ION, CHLORIDE ION, COPPER (II) ION, ...
著者Ferraroni, M, Rypniewski, W, Wilson, K.S, Orioli, P.L, Viezzoli, M.S, Banci, L, Bertini, I, Mangani, S.
登録日1999-04-16
公開日1999-04-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献The crystal structure of the monomeric human SOD mutant F50E/G51E/E133Q at atomic resolution. The enzyme mechanism revisited.
J.Mol.Biol., 288, 1999
4A7S
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BU of 4a7s by Molmil
Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group
分子名称: 5-FLUOROURIDINE, ACETATE ION, COPPER (II) ION, ...
著者Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S.
登録日2011-11-14
公開日2012-12-05
最終更新日2013-05-08
実験手法X-RAY DIFFRACTION (1.06 Å)
主引用文献Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
2C9V
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BU of 2c9v by Molmil
Atomic resolution structure of Cu-Zn Human Superoxide dismutase
分子名称: COPPER (II) ION, SODIUM ION, SULFATE ION, ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine, J.S, Hasnain, S.S.
登録日2005-12-14
公開日2005-12-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.07 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
4L05
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BU of 4l05 by Molmil
Cu/Zn superoxide dismutase from Brucella abortus
分子名称: COPPER (I) ION, COPPER (II) ION, GLYCEROL, ...
著者Shin, D.S, Didonato, M, Pratt, A.J, Bruns, C.K, Cabelli, D.E, Kroll, J.S, Belzer, C.A, Tabatabai, L.B, Tainer, J.A, Getzoff, E.D.
登録日2013-05-30
公開日2013-10-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.098 Å)
主引用文献Structural, Functional, and Immunogenic Insights on Cu,Zn Superoxide Dismutase Pathogenic Virulence Factors from Neisseria meningitidis and Brucella abortus.
J.Bacteriol., 197, 2015
3KBE
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BU of 3kbe by Molmil
Metal-free C. elegans Cu,Zn Superoxide Dismutase
分子名称: Superoxide dismutase [Cu-Zn]
著者Pakhomova, O.N, Taylor, A.B, Schuermann, J.P, Culotta, V.L, Hart, P.J.
登録日2009-10-20
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献X-ray Crystal Structure of C. elegans Cu,Zn Superoxide Dismutase
To be Published
2V0A
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BU of 2v0a by Molmil
Atomic resolution crystal structure of Human Superoxide Dismutase
分子名称: ACETATE ION, COPPER (II) ION, SULFATE ION, ...
著者Strange, R.W, Antonyuk, S, Yong, C.W, Smith, W, Hasnain, S.S.
登録日2007-05-11
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Molecular Dynamics Using Atomic-Resolution Structure Reveal Structural Fluctuations that May Lead to Polymerization of Human Cu-Zn Superoxide Dismutase.
Proc.Natl.Acad.Sci.USA, 104, 2007
1Q0E
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BU of 1q0e by Molmil
Atomic resolution (1.15 ) crystal structure of bovine copper, zinc superoxide dismutase
分子名称: COPPER (II) ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Hough, M.A, Hasnain, S.S.
登録日2003-07-16
公開日2003-09-23
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Structure of fully reduced bovine copper zinc superoxide dismutase at 1.15 A.
Structure, 11, 2003
3CE1
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BU of 3ce1 by Molmil
Crystal Structure of the Cu/Zn Superoxide Dismutase from Cryptococcus liquefaciens Strain N6
分子名称: ACETATE ION, COPPER (II) ION, Superoxide dismutase [Cu-Zn], ...
著者Teh, A.H, Kanamasa, S, Kajiwara, S, Kumasaka, T.
登録日2008-02-27
公開日2008-08-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of Cu/Zn superoxide dismutase from the heavy-metal-tolerant yeast Cryptococcus liquefaciens strain N6.
Biochem.Biophys.Res.Commun., 374, 2008
4A7Q
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BU of 4a7q by Molmil
Structure of human I113T SOD1 mutant complexed with 4-(4-methyl-1,4- diazepan-1-yl)quinazoline in the p21 space group.
分子名称: 4-(4-METHYL-1,4-DIAZEPAN-1-YL)QUINAZOLINE, COPPER (II) ION, SULFATE ION, ...
著者Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S.
登録日2011-11-14
公開日2012-10-24
最終更新日2013-08-28
実験手法X-RAY DIFFRACTION (1.22 Å)
主引用文献X-Ray Crystallography and Computational Docking for the Detection and Development of Protein-Ligand Interactions.
Curr.Med.Chem., 20, 2013
4A7G
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BU of 4a7g by Molmil
Structure of human I113T SOD1 mutant complexed with 4-methylpiperazin- 1-yl)quinazoline in the p21 space group.
分子名称: 4-(4-METHYLPIPERAZIN-1-YL)QUINAZOLINE, ACETATE ION, COPPER (II) ION, ...
著者Wright, G.S.A, Kershaw, N.M, Sharma, R, Antonyuk, S.V, Strange, R.W, Berry, N.G, O'Neil, P.M, Hasnain, S.S.
登録日2011-11-14
公開日2012-10-24
最終更新日2019-10-09
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献X-ray crystallography and computational docking for the detection and development of protein-ligand interactions.
Curr.Med.Chem., 20, 2013
2C9U
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1.24 Angstroms resolution structure of as-isolated Cu-Zn Human Superoxide dismutase
分子名称: ACETATE ION, COPPER (II) ION, SULFATE ION, ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S.
登録日2005-12-14
公開日2005-12-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
2C9S
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BU of 2c9s by Molmil
1.24 Angstroms resolution structure of Zn-Zn Human Superoxide dismutase
分子名称: ACETATE ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Strange, R.W, Antonyuk, S.V, Hough, M.A, Doucette, P.A, Valentine S, J.S, Hasnain, S.
登録日2005-12-14
公開日2005-12-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu-Zn, Zn-Zn and as-Isolated Wild-Type Enzymes.
J.Mol.Biol., 356, 2006
6Z3V
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BU of 6z3v by Molmil
A4V mutant of human SOD1 bound with N-aryl benzoisoselenazolone derivative 13 in P21 space group
分子名称: 5-fluoranyl-~{N}-(3-morpholin-4-ylcarbonylphenyl)-2-selanyl-benzamide, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Amporndanai, K, Hasnain, S.S.
登録日2020-05-22
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis.
Ebiomedicine, 59, 2020
4BCY
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BU of 4bcy by Molmil
Monomeric Human Cu,Zn Superoxide dismutase, mutation H43F
分子名称: CADMIUM ION, CHLORIDE ION, COPPER (II) ION, ...
著者Awad, W, Saraboji, K, Danielsson, J, Lang, L, Kurnik, M, Marklund, S.L, Oliveberg, M, Logan, D.T.
登録日2012-10-03
公開日2013-02-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.272 Å)
主引用文献Global Structural Motions from the Strain of a Single Hydrogen Bond.
Proc.Natl.Acad.Sci.USA, 110, 2013
5O3Y
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BU of 5o3y by Molmil
SOD1 bound to Ebsulfur
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION, ...
著者Capper, M.J, Wright, G.S.A, Antonyuk, S.V, Hasnain, S.S.
登録日2017-05-25
公開日2018-06-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.
Nat Commun, 9, 2018
2VR6
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BU of 2vr6 by Molmil
Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution
分子名称: COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ...
著者Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J.
登録日2008-03-28
公開日2008-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
2AQP
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BU of 2aqp by Molmil
CU/ZN superoxide dismutase from neisseria meningitidis E73A mutant
分子名称: 1,2-ETHANEDIOL, COPPER (I) ION, Superoxide dismutase [Cu-Zn], ...
著者DiDonato, M, Kassmann, C.J, Bruns, C.K, Cabelli, D.E, Cao, Z, Tabatabai, L.B, Kroll, J.S, Getzoff, E.D.
登録日2005-08-18
公開日2006-10-31
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献CU/ZN superoxide dismutase from neisseria meningitidis E73A mutant
To be Published
1OZU
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BU of 1ozu by Molmil
Crystal Structure of Familial ALS Mutant S134N of human Cu,Zn Superoxide Dismutase (CuZnSOD) to 1.3A resolution
分子名称: SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION
著者Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J.
登録日2003-04-09
公開日2003-05-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS
Nat.Struct.Biol., 10, 2003
3KBF
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BU of 3kbf by Molmil
C. elegans Cu,Zn Superoxide Dismutase
分子名称: COPPER (II) ION, SULFATE ION, Superoxide dismutase [Cu-Zn], ...
著者Pakhomova, O.N, Taylor, A.B, Schuermann, J.P, Culotta, V.L, Hart, P.J.
登録日2009-10-20
公開日2010-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献X-ray Crystal Structure of C. elegans Cu,Zn Superoxide Dismutase
To be Published
7T8G
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BU of 7t8g by Molmil
G93A mutant of human SOD1 bound with MR6-8-2 in P21 space group
分子名称: ACETATE ION, SELENIUM ATOM, SULFATE ION, ...
著者Amporndanai, K, Hasnain, S.S.
登録日2021-12-16
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Disease Onset and its course are delayed by on-target Cellular SOD1 Engagement of Organo-selenium drug compounds for Amyotrophic Lateral Sclerosis
To Be Published
1F1G
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Crystal structure of yeast cuznsod exposed to nitric oxide
分子名称: COPPER (II) ION, COPPER-ZINC SUPEROXIDE DISMUTASE, PHOSPHATE ION, ...
著者Hart, P.J, Ogihara, N.L, Liu, H, Nersissian, A.M, Valentine, J.S, Eisenberg, D.
登録日2000-05-18
公開日2002-12-12
最終更新日2017-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献A structure-based mechanism for copper-zinc superoxide dismutase.
Biochemistry, 38, 1999

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