5O3Y
SOD1 bound to Ebsulfur
Summary for 5O3Y
Entry DOI | 10.2210/pdb5o3y/pdb |
Descriptor | Superoxide dismutase [Cu-Zn], ZINC ION, ~{N}-phenyl-2-sulfanyl-benzamide, ... (5 entities in total) |
Functional Keywords | oxidoreductase drug discovery als mnd, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 32567.48 |
Authors | Capper, M.J.,Wright, G.S.A.,Antonyuk, S.V.,Hasnain, S.S. (deposition date: 2017-05-25, release date: 2018-06-13, Last modification date: 2024-01-17) |
Primary citation | Capper, M.J.,Wright, G.S.A.,Barbieri, L.,Luchinat, E.,Mercatelli, E.,McAlary, L.,Yerbury, J.J.,O'Neill, P.M.,Antonyuk, S.V.,Banci, L.,Hasnain, S.S. The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation. Nat Commun, 9:1693-1693, 2018 Cited by PubMed: 29703933DOI: 10.1038/s41467-018-04114-x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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