PDB: 255 件ウェブページステータス検索Chemie searchBIRD

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1DVN	LATENT FORM OF PLASMINOGEN ACTIVATOR INHIBITOR-1 (PAI-1) 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Stout, T.J, Graham, H, Buckley, D.I, Matthews, D.J. 登録日 2000-01-21 公開日 2000-09-13 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of active and latent PAI-1: a possible stabilizing role for chloride ions. Biochemistry, 39, 2000
1C5G	PLASMINOGEN ACTIVATOR INHIBITOR-1 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Goldsmith, E.J. 登録日 1999-12-07 公開日 1999-12-17 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition. Nat.Struct.Biol., 2, 1995
1DB2	CRYSTAL STRUCTURE OF NATIVE PLASMINOGEN ACTIVATOR INHIBITOR-1 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Nar, H, Bauer, M, Stassen, J.M, Lang, D, Gils, A, Declerck, P. 登録日 1999-11-02 公開日 1999-11-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Plasminogen activator inhibitor 1. Structure of the native serpin, comparison to its other conformers and implications for serpin inactivation. J.Mol.Biol., 297, 2000
1D5S	CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER 分子名称: P1-ARG ANTITRYPSIN 著者 Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P. 登録日 1999-10-11 公開日 2000-04-02 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Cleaved antitrypsin polymers at atomic resolution. Protein Sci., 9, 2000
1QMN	Alpha1-antichymotrypsin serpin in the delta conformation (partial loop insertion) 分子名称: ALPHA-1-ANTICHYMOTRYPSIN 著者 Gooptu, B, Hazes, B, Lomas, D.A. 登録日 1999-10-04 公開日 2000-01-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Inactive Conformation of the Serpin Alpha1-Antichymotrypsin Indicates Two-Stage Insertion of the Reactive Loop: Implications for Inhibitory Function and Conformational Disease Proc.Natl.Acad.Sci.USA, 97, 2000
1QMB	Cleaved alpha-1-antitrypsin polymer 分子名称: ALPHA-1-ANTITRYPSIN 著者 Huntington, J.A, Pannu, N.S, Hazes, B, Read, R.J, Lomas, D.A, Carrell, R.W. 登録日 1999-09-24 公開日 2000-02-06 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 A 2.6A Structure of a Serpin Polymer and Implications for Conformational Disease J.Mol.Biol., 293, 1999
1QLP	2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS 分子名称: ALPHA-1-ANTITRYPSIN 著者 Elliott, P.R, Pei, X.Y, Dafforn, T, Read, R.J, Carrell, R.W, Lomas, D.A. 登録日 1999-09-10 公開日 1999-09-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease. Protein Sci., 9, 2000
9PAI	CLEAVED SUBSTRATE VARIANT OF PLASMINOGEN ACTIVATOR INHIBITOR-1 分子名称: PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-1) residues 19-364, PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-1) residues 365-397 著者 Aertgeerts, K, De Bondt, H.L, De Ranter, C.J, Declerck, P.J. 登録日 1999-03-11 公開日 1999-03-19 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanisms contributing to the conformational and functional flexibility of plasminogen activator inhibitor-1. Nat.Struct.Biol., 2, 1995
1B3K	Plasminogen activator inhibitor-1 分子名称: PLASMINOGEN ACTIVATOR INHIBITOR-1 著者 Sharp, A.M, Stein, P.E, Pannu, N.S, Read, R.J. 登録日 1998-12-11 公開日 1999-12-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 The active conformation of plasminogen activator inhibitor 1, a target for drugs to control fibrinolysis and cell adhesion. Structure Fold.Des., 7, 1999
1BY7	HUMAN PLASMINOGEN ACTIVATOR INHIBITOR-2. LOOP (66-98) DELETION MUTANT 分子名称: PROTEIN (PLASMINOGEN ACTIVATOR INHIBITOR-2) 著者 Harrop, S.J, King, G.C, Mabbutt, B.C, Curmi, P.M.G. 登録日 1998-10-27 公開日 1999-10-24 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The crystal structure of plasminogen activator inhibitor 2 at 2.0 A resolution: implications for serpin function. Structure Fold.Des., 7, 1999
1BR8	IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN 分子名称: PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE) 著者 Skinner, R, Chang, W.S.W, Jin, L, Pei, X.Y, Huntington, J.A, Abrahams, J.P, Carrell, R.W, Lomas, D.A. 登録日 1998-08-26 公開日 1998-09-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin. J.Mol.Biol., 283, 1998
1A7C	HUMAN PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 IN COMPLEX WITH A PENTAPEPTIDE 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-D-ribopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PENTAPEPTIDE, ... 著者 Xue, Y, Inghardt, T, Sjolin, L, Deinum, J. 登録日 1998-03-12 公開日 1999-03-23 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide Structure, 6, 1998
1SEK	THE STRUCTURE OF ACTIVE SERPIN K FROM MANDUCA SEXTA AND A MODEL FOR SERPIN-PROTEASE COMPLEX FORMATION 分子名称: SERPIN K 著者 Li, J, Wang, Z, Canagarajah, B, Jiang, H, Kanost, M, Goldsmith, E.J. 登録日 1998-03-06 公開日 1999-03-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The structure of active serpin 1K from Manduca sexta. Structure Fold.Des., 7, 1999
1AZX	ANTITHROMBIN/PENTASACCHARIDE COMPLEX 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,4-di-O-methyl-2,6-di-O-sulfo-alpha-D-glucopyranose-(1-4)-2,3-di-O-methyl-beta-D-glucopyranuronic acid-(1-4)-2,3,6-tri-O-sulfo-alpha-D-glucopyranose-(1-4)-3-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2,3,6-tri-O-sulfo-alpha-D-glucopyranoside, ANTITHROMBIN 著者 Jin, L, Abrahams, J.P, Skinner, R, Petitou, M, Pike, R.N, Carrell, R.W. 登録日 1997-11-23 公開日 1999-01-13 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The anticoagulant activation of antithrombin by heparin. Proc.Natl.Acad.Sci.USA, 94, 1997
3CAA	CLEAVED ANTICHYMOTRYPSIN A347R 分子名称: ANTICHYMOTRYPSIN 著者 Lukacs, C.M, Christianson, D.W. 登録日 1997-08-18 公開日 1998-02-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
4CAA	CLEAVED ANTICHYMOTRYPSIN T345R 分子名称: ANTICHYMOTRYPSIN 著者 Lukacs, C.M, Christianson, D.W. 登録日 1997-08-14 公開日 1998-02-25 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
1AS4	CLEAVED ANTICHYMOTRYPSIN A349R 分子名称: ACETATE ION, ANTICHYMOTRYPSIN 著者 Lukacs, C.M, Christianson, D.W. 登録日 1997-08-12 公開日 1998-02-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
1ATU	UNCLEAVED ALPHA-1-ANTITRYPSIN 分子名称: ALPHA-1-ANTITRYPSIN 著者 Ryu, S.-E, Choi, H.-J. 登録日 1997-05-11 公開日 1997-08-20 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A. Structure, 4, 1996
2ANT	THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE 分子名称: 2-acetamido-2-deoxy-beta-D-allopyranose, ANTITHROMBIN 著者 Skinner, R, Abrahams, J.-P, Whisstock, J.C, Lesk, A.M, Carrell, R.W, Wardell, M.R. 登録日 1997-01-28 公開日 1997-06-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site. J.Mol.Biol., 266, 1997
1KCT	ALPHA1-ANTITRYPSIN 分子名称: ALPHA1-ANTITRYPSIN 著者 Song, H.K, Suh, S.W. 登録日 1996-08-06 公開日 1997-01-11 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Crystal structure of an uncleaved alpha 1-antitrypsin reveals the conformation of its inhibitory reactive loop. FEBS Lett., 377, 1995
1PSI	Intact recombined alpha1-antitrypsin mutant PHE 51 to LEU 分子名称: ALPHA=1=-ANTITRYPSIN 著者 Abrahams, J.P, Elliott, P.R, Lomas, D.A, Carrell, R.W. 登録日 1996-06-11 公開日 1996-12-07 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Inhibitory conformation of the reactive loop of alpha 1-antitrypsin. Nat.Struct.Biol., 3, 1996
1ANT	BIOLOGICAL IMPLICATIONS OF A 3 ANGSTROMS STRUCTURE OF DIMERIC ANTITHROMBIN 分子名称: ANTITHROMBIN 著者 Carrell, R.W, Stein, P.E, Fermi, G, Wardell, M.R. 登録日 1994-02-28 公開日 1995-01-26 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Biological implications of a 3 A structure of dimeric antithrombin. Structure, 2, 1994
1ATH	THE INTACT AND CLEAVED HUMAN ANTITHROMBIN III COMPLEX AS A MODEL FOR SERPIN-PROTEINASE INTERACTIONS 分子名称: ANTITHROMBIN III 著者 Schreuder, H.A, Hol, W.G.J. 登録日 1993-12-14 公開日 1995-02-07 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions. Nat.Struct.Biol., 1, 1994
2ACH	CRYSTAL STRUCTURE OF CLEAVED HUMAN ALPHA1-ANTICHYMOTRYPSIN AT 2.7 ANGSTROMS RESOLUTION AND ITS COMPARISON WITH OTHER SERPINS 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA 1-ANTICHYMOTRYPSIN, PHOSPHATE ION, ... 著者 Baumann, U, Huber, R, Bode, W, Grosse, D, Lesjak, M, Laurell, C.B. 登録日 1993-04-26 公開日 1993-07-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of cleaved human alpha 1-antichymotrypsin at 2.7 A resolution and its comparison with other serpins. J.Mol.Biol., 218, 1991
1ATT	CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION 分子名称: ANTITHROMBIN III 著者 Mourey, L, Samama, J.P, Delarue, M, Moras, D. 登録日 1993-03-29 公開日 1994-07-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution. J.Mol.Biol., 232, 1993

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