1QMN

Alpha1-antichymotrypsin serpin in the delta conformation (partial loop insertion)

Summary for 1QMN

Entry DOI	10.2210/pdb1qmn/pdb
Related	1AS4 2ACH 3CAA 4CAA
Descriptor	ALPHA-1-ANTICHYMOTRYPSIN (1 entity in total)
Functional Keywords	serpin, serine proteinase inhibitor, hydrolase inhibitor loop-sheet polymerization, emphysema, disease mutation, acute phase protein, conformational disease, hydrolase inhibitor
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	45353.69
Authors	Gooptu, B.,Hazes, B.,Lomas, D.A. (deposition date: 1999-10-04, release date: 2000-01-17, Last modification date: 2023-12-13)
Primary citation	Gooptu, B.,Hazes, B.,Chang, W.-S.W.,Dafforn, T.R.,Carrell, R.W.,Read, R.J.,Lomas, D.A. Inactive Conformation of the Serpin Alpha1-Antichymotrypsin Indicates Two-Stage Insertion of the Reactive Loop: Implications for Inhibitory Function and Conformational Disease Proc.Natl.Acad.Sci.USA, 97:67-, 2000 Cited by PubMed: 10618372 DOI: 10.1073/PNAS.97.1.67 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.27 Å)

Structure validation