1QLP
2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS
Replaces: 2PSISummary for 1QLP
Entry DOI | 10.2210/pdb1qlp/pdb |
Related | 1ATU 1KCT 1PSI 2PSI 7API 8API 9API |
Descriptor | ALPHA-1-ANTITRYPSIN (2 entities in total) |
Functional Keywords | serine protease inhibitor, serpin, glycoprotein, polymorphism, emphysema, disease mutation, acute phase |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 44380.44 |
Authors | Elliott, P.R.,Pei, X.Y.,Dafforn, T.,Read, R.J.,Carrell, R.W.,Lomas, D.A. (deposition date: 1999-09-10, release date: 1999-09-27, Last modification date: 2023-12-13) |
Primary citation | Elliott, P.R.,Pei, X.Y.,Dafforn, T.R.,Lomas, D.A. Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease. Protein Sci., 9:1274-1281, 2000 Cited by PubMed: 10933492DOI: 10.1110/ps.9.7.1274 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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