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7D7V
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Crystal Structure of the Domain1 of NAD+ Riboswitch with nicotinamide adenine dinucleotide (NAD+) and U1A protein
分子名称: 17delU1A (58-MER), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Chen, H, Ren, A.M.
登録日2020-10-06
公開日2020-11-25
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural distinctions between NAD+ riboswitch domains 1 and 2 determine differential folding and ligand binding.
Nucleic Acids Res., 48, 2020
7D2Y
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complex of two RRM domains
分子名称: Embryonic developmental protein tofu-6, RRM2, SULFATE ION
著者Wang, X, Liao, S, Xu, C.
登録日2020-09-17
公開日2021-08-25
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
7D1L
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BU of 7d1l by Molmil
complex structure of two RRM domains
分子名称: Embryonic developmental protein tofu-6, Uncharacterized protein
著者Wang, X, Liao, S, Xu, C.
登録日2020-09-14
公開日2021-08-25
最終更新日2021-10-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular basis for PICS-mediated piRNA biogenesis and cell division.
Nat Commun, 12, 2021
7CSZ
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BU of 7csz by Molmil
Crystal structure of the N-terminal tandem RRM domains of RBM45 in complex with single-stranded DNA
分子名称: DNA (5'-D(*CP*GP*AP*CP*GP*GP*GP*AP*CP*GP*C)-3'), RNA-binding protein 45
著者Chen, X, Yang, Z, Wang, W, Wang, M.
登録日2020-08-17
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Nucleic Acids Res., 49, 2021
7CSX
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Crystal structure of the N-terminal tandem RRM domains of RBM45
分子名称: RNA-binding protein 45
著者Chen, X, Yang, Z, Wang, W, Wang, M.
登録日2020-08-17
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for RNA recognition by the N-terminal tandem RRM domains of human RBM45.
Nucleic Acids Res., 49, 2021
7C36
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BU of 7c36 by Molmil
c-Myc DNA binding protein structure
分子名称: RNA-binding motif, single-stranded-interacting protein 1
著者Aggarwal, P, Bhavesh, N.S.
登録日2020-05-11
公開日2021-05-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Hinge like domain motion facilitates human RBMS1 protein binding to proto-oncogene c-myc promoter.
Nucleic Acids Res., 49, 2021
7C08
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Crystal structure of S34Y mutant of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
分子名称: RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ...
著者Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
登録日2020-04-30
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
7C07
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Crystal structure of yeast U2AF1 complex bound to 5'-AAGGU RNA.
分子名称: RNA (5'-R(*U*AP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ...
著者Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
登録日2020-04-30
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
7C06
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Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.
分子名称: RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), Splicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, ...
著者Yoshida, H, Park, S.Y, Urano, T, Obayashi, E.
登録日2020-04-30
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.02 Å)
主引用文献Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11, 2020
7BTB
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BU of 7btb by Molmil
Cryo-EM structure of pre-60S ribosome from Saccharomyces cerevisiae rpl4delta63-87 strain at 3.22 Angstroms resolution(state R2)
分子名称: 60S ribosomal protein L11-A, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ...
著者Li, Y, Wilson, D.M.
登録日2020-04-01
公開日2020-10-28
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Structural insights into assembly of the ribosomal nascent polypeptide exit tunnel.
Nat Commun, 11, 2020
7B9V
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BU of 7b9v by Molmil
Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound
分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ...
著者Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K.
登録日2020-12-14
公開日2021-03-10
最終更新日2021-04-14
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis for conformational equilibrium of the catalytic spliceosome.
Mol.Cell, 81, 2021
7B0Y
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Structure of a transcribing RNA polymerase II-U1 snRNP complex
分子名称: 145-nt RNA, DNA-directed RNA polymerase II subunit D, DNA-directed RNA polymerase II subunit E, ...
著者Zhang, S, Aibara, S, Vos, S.M, Agafonov, D.E, Luehrmann, R, Cramer, P.
登録日2020-11-23
公開日2021-01-13
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of a transcribing RNA polymerase II-U1 snRNP complex.
Science, 371, 2021
7ASE
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BU of 7ase by Molmil
43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase
分子名称: 18S, 40S ribosomal protein S10, putative, ...
著者Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y.
登録日2020-10-27
公開日2021-04-14
最終更新日2021-04-21
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts.
Cell Rep, 33, 2020
7AEP
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BU of 7aep by Molmil
Solution structure of U1-A RRM2 (190-282)
分子名称: U1 small nuclear ribonucleoprotein A
著者Campagne, S, Allain, F.H.
登録日2020-09-18
公開日2021-02-03
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献An in vitro reconstituted U1 snRNP allows the study of the disordered regions of the particle and the interactions with proteins and ligands.
Nucleic Acids Res., 49, 2021
7ABI
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BU of 7abi by Molmil
Human pre-Bact-2 spliceosome
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Beta-catenin-like protein 1, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2021-02-10
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7ABH
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BU of 7abh by Molmil
Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)
分子名称: Cell division cycle 5-like protein, DNA/RNA-binding protein KIN17, MINX M3 pre-mRNA, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2020-12-09
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7ABG
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BU of 7abg by Molmil
Human pre-Bact-1 spliceosome
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-07
公開日2020-12-23
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7AAV
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BU of 7aav by Molmil
Human pre-Bact-2 spliceosome core structure
分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, D-chiro inositol hexakisphosphate, ...
著者Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R.
登録日2020-09-04
公開日2020-12-09
最終更新日2020-12-30
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation.
Science, 370, 2020
7AAO
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BU of 7aao by Molmil
Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
分子名称: U2 snRNP auxiliary factor large subunit
著者Kawale, A.A, Kang, H.S, Sattler, M.
登録日2020-09-04
公開日2021-10-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
To Be Published
7AAF
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Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
分子名称: U2 snRNP auxiliary factor large subunit
著者Kawale, A.A, Kang, H.S, Sattler, M.
登録日2020-09-04
公開日2021-10-06
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
To Be Published
7A5P
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BU of 7a5p by Molmil
Human C Complex Spliceosome - Medium-resolution PERIPHERY
分子名称: Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ...
著者Bertram, K, Kastner, B.
登録日2020-08-21
公開日2020-10-14
実験手法ELECTRON MICROSCOPY (5 Å)
主引用文献Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome.
Mol.Cell, 80, 2020
7A09
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Structure of a human ABCE1-bound 43S pre-initiation complex - State III
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-08-07
公開日2020-10-14
最終更新日2021-01-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6ZVJ
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BU of 6zvj by Molmil
Structure of a human ABCE1-bound 43S pre-initiation complex - State II
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Kratzat, H, Mackens-Kiani, T, Ameismeier, A, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-24
公開日2020-10-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6ZU9
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BU of 6zu9 by Molmil
Structure of a yeast ABCE1-bound 48S initiation complex
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ...
著者Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-22
公開日2020-10-28
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献A structural inventory of native ribosomal ABCE1-43S pre-initiation complexes.
Embo J., 40, 2021
6ZP4
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BU of 6zp4 by Molmil
SARS-CoV-2 Nsp1 bound to a human 43S preinitiation ribosome complex - state 2
分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ...
著者Thoms, M, Buschauer, R, Ameismeier, M, Denk, T, Kratzat, H, Mackens-Kiani, T, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R.
登録日2020-07-08
公開日2020-07-29
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Science, 369, 2020

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