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7C06

Crystal structure of yeast U2AF1 complex bound to 3' splice site RNA, 5'-UAGGU.

Summary for 7C06
Entry DOI10.2210/pdb7c06/pdb
DescriptorSplicing factor U2AF 23 kDa subunit, Splicing factor U2AF 59 kDa subunit, RNA (5'-R(*U*UP*AP*GP*GP*U)-3'), ... (4 entities in total)
Functional Keywordspre-mrna, splicing, intron, 3' splice site, zinc-finger, splicing-rna complex, splicing/rna
Biological sourceSchizosaccharomyces pombe 972h- (Fission yeast)
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Total number of polymer chains27
Total formula weight314271.93
Authors
Yoshida, H.,Park, S.Y.,Urano, T.,Obayashi, E. (deposition date: 2020-04-30, release date: 2020-09-30, Last modification date: 2023-11-29)
Primary citationYoshida, H.,Park, S.Y.,Sakashita, G.,Nariai, Y.,Kuwasako, K.,Muto, Y.,Urano, T.,Obayashi, E.
Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1.
Nat Commun, 11:4744-4744, 2020
Cited by
PubMed: 32958768
DOI: 10.1038/s41467-020-18559-6
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.02 Å)
Structure validation

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