PDB: 858 resultsInfo pagesStatus searchChemie searchBIRD

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7QTT	Structural organization of a late activated human spliceosome (Baqr, core region) Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... Authors: Cretu, C, Pena, V. Deposit date: 2022-01-15 Release date: 2023-05-10 Last modified: 2023-06-14 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of catalytic activation in human splicing. Nature, 617, 2023
7QR4	human CPEB3 HDV-like ribozyme Descriptor: RNA CPEB3 ribozyme, U1 small nuclear ribonucleoprotein A Authors: Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O. Deposit date: 2022-01-17 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.83 Å) Cite: Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes Biorxiv, 2022
7QR3	Chimpanzee CPEB3 HDV-like ribozyme Descriptor: GLYCEROL, POTASSIUM ION, U1 small nuclear ribonucleoprotein A, ... Authors: Przytula-Mally, A.I, Engilberge, S, Johannsen, S, Olieric, V, Masquida, B, Sigel, R.K.O. Deposit date: 2022-01-10 Release date: 2022-10-26 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.18 Å) Cite: Anticodon-like loop-mediated dimerization in the crystal structures of HdV-like CPEB3 ribozymes Biorxiv, 2022
7QP7	Structure of the human 48S initiation complex in closed state (h48S AUG closed) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) Descriptor: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... Authors: Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. Deposit date: 2022-01-03 Release date: 2022-05-11 Last modified: 2024-04-24 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
7QDE	NMR structure of Npl3 RRM12 bound to the AUCCAGUGGAA RNA Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*GP*UP*GP*GP*AP*A)-3') Authors: Allain, F.H.-T, Clery, A, Moursy, A. Deposit date: 2021-11-26 Release date: 2022-12-21 Last modified: 2024-01-10 Method: SOLUTION NMR Cite: RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing. Nat Commun, 14, 2023
7QDD	NMR structure of Npl3 RRM1 bound to the AUCCAA RNA Descriptor: Nucleolar protein 3, RNA (5'-R(*AP*UP*CP*CP*AP*A)-3') Authors: Clery, A, Allain, F.H.-T, Moursy, A. Deposit date: 2021-11-26 Release date: 2022-10-26 Last modified: 2024-01-10 Method: SOLUTION NMR Cite: RNA recognition by Npl3p reveals U2 snRNA-binding compatible with a chaperone role during splicing. Nat Commun, 14, 2023
7Q8A	Crystal structure of tandem domain RRM1-2 of FUBP-interacting repressor (FIR) bound to FUSE ssDNA fragment Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(P*GP*T)-3'), Poly(U)-binding-splicing factor PUF60, ... Authors: Ni, X, Joerger, A.C, Chaikuad, A, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2021-11-10 Release date: 2022-11-09 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Crystal structure of tandem domain RRM1-2 of FIR bound to FUSE ssDNA fragment To Be Published
7Q4O	Substrate-bound A-like U2 snRNP Descriptor: BPS oligo, PHD finger-like domain-containing protein 5A, Splicing factor 3A subunit 2, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-11-01 Release date: 2022-03-30 Method: ELECTRON MICROSCOPY (2.2 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7Q4L	The solution structure of hsDND1 RRM12 bound to CUUAUUUG RNA Descriptor: Dead end protein homolog 1, RNA (5'-R(*CP*UP*UP*AP*UP*UP*UP*G)-3') Authors: Duszczyk, M.M, Allain, F.H.T. Deposit date: 2021-10-31 Release date: 2022-05-04 Last modified: 2022-10-19 Method: SOLUTION NMR Cite: The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation. Nat Commun, 13, 2022
7Q3L	Human 17S U2 snRNP 5' domain Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... Authors: Tholen, J, Galej, W.P. Deposit date: 2021-10-28 Release date: 2022-03-30 Method: ELECTRON MICROSCOPY (2.3 Å) Cite: Structural basis of branch site recognition by the human spliceosome. Science, 375, 2022
7Q33	Solution structure of RBM39 RRM2 bound to 5'-AGCUUUG-3 Descriptor: RNA (5'-R(*AP*GP*CP*UP*UP*UP*G)-3'), RNA-binding protein 39 Authors: Campagne, S, Allain, F.H. Deposit date: 2021-10-26 Release date: 2023-02-08 Last modified: 2023-09-20 Method: SOLUTION NMR Cite: Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39. Nat Commun, 14, 2023
7PY2	Structure of pathological TDP-43 filaments from ALS with FTLD Descriptor: TAR DNA-binding protein 43 Authors: Arseni, D, Hasegawa, H, Murzin, A.G, Kametani, F, Arai, M, Yoshida, M, Falcon, B. Deposit date: 2021-10-08 Release date: 2021-12-15 Last modified: 2022-01-19 Method: ELECTRON MICROSCOPY (2.6 Å) Cite: Structure of pathological TDP-43 filaments from ALS with FTLD. Nature, 601, 2022
7PU5	Structure of SFPQ-NONO complex Descriptor: MAGNESIUM ION, Non-POU domain-containing octamer-binding protein, Splicing factor, ... Authors: Fribourg, S. Deposit date: 2021-09-28 Release date: 2022-03-16 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.999 Å) Cite: Crystal structure of SFPQ-NONO heterodimer. Biochimie, 198, 2022
7PDV	Crystal structure of RBM5 RRM1-zinc finger in complex with RNA Descriptor: RNA (5'-R(P*UP*GP*GP*CP*UP*CP*UP*UP*CP*U)-3'), RNA binding motif protein 5 isoform 1, ZINC ION Authors: Soni, K, Jagtap, P.K.A, Sattler, M. Deposit date: 2021-08-08 Release date: 2022-08-24 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.49 Å) Cite: Structural basis for specific RNA recognition by the alternative splicing factor RBM5. Nat Commun, 14, 2023
7PCV	Crystal structure of RBM5 RRM1-zinc finger Descriptor: RNA-binding protein 5, ZINC ION Authors: Soni, K, Jagtap, P.K.A, Sattler, M. Deposit date: 2021-08-04 Release date: 2022-08-17 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.42 Å) Cite: Structural basis for specific RNA recognition by the alternative splicing factor RBM5. Nat Commun, 14, 2023
7OQE	Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A), Cold sensitive U2 snRNA suppressor 1, ... Authors: Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. Deposit date: 2021-06-03 Release date: 2021-08-11 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (5.9 Å) Cite: Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
7OQC	The U1 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) Descriptor: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A),ACT1 pre-mRNA (delta BS-A), Pre-mRNA-processing factor 39, ... Authors: Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. Deposit date: 2021-06-03 Release date: 2021-08-11 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
7OQB	The U2 part of Saccharomyces cerevisiae spliceosomal pre-A complex (delta BS-A ACT1) Descriptor: ACT1 pre-mRNA (delta-BS-A), Cold sensitive U2 snRNA suppressor 1, Pre-mRNA-processing ATP-dependent RNA helicase PRP5, ... Authors: Zhang, Z, Rigo, N, Dybkov, O, Fourmann, J, Will, C.L, Kumar, V, Urlaub, H, Stark, H, Luehrmann, R. Deposit date: 2021-06-03 Release date: 2021-08-11 Last modified: 2021-09-22 Method: ELECTRON MICROSCOPY (9 Å) Cite: Structural insights into how Prp5 proofreads the pre-mRNA branch site. Nature, 596, 2021
7ONB	Structure of the U2 5' module of the A3'-SSA complex Descriptor: MINX, PHD finger-like domain-containing protein 5A, RNU2, ... Authors: Cretu, C, Pena, V. Deposit date: 2021-05-25 Release date: 2021-08-04 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
7OHX	Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL34 expression shut down, population A Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... Authors: Milkereit, P, Poell, G. Deposit date: 2021-05-11 Release date: 2021-11-03 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHW	Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL25 expression shut down, population B Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... Authors: Milkereit, P, Poell, G. Deposit date: 2021-05-11 Release date: 2021-11-03 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHV	Nog1-TAP associated immature ribosomal particles from S. cerevisiae after rpL2 expression shut down, population C Descriptor: 25S rRNA, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, 5.8S rRNA, ... Authors: Milkereit, P, Poell, G. Deposit date: 2021-05-11 Release date: 2021-11-03 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (3.9 Å) Cite: Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHS	Nog1-TAP associated immature ribosomal particle population F from S. cerevisiae Descriptor: 25S rRNA, 5.8S rRNA, 60S ribosomal protein L13-A, ... Authors: Milkereit, P, Poell, G. Deposit date: 2021-05-11 Release date: 2021-11-03 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (4.38 Å) Cite: Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021
7OHR	Nog1-TAP associated immature ribosomal particle population E from S. cerevisiae Descriptor: 25S rRNA, 25S rRNA (cytosine(2870)-C(5))-methyltransferase, 27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase, ... Authors: Milkereit, P, Poell, G. Deposit date: 2021-05-11 Release date: 2021-11-10 Last modified: 2021-12-08 Method: ELECTRON MICROSCOPY (4.72 Å) Cite: Analysis of subunit folding contribution of three yeast large ribosomal subunit proteins required for stabilisation and processing of intermediate nuclear rRNA precursors. Plos One, 16, 2021

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