7S3C
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7S3A
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7SN6
| U2AF65 UHM BOUND TO SF3B155 ULM5 | 分子名称: | ISOPROPYL ALCOHOL, Splicing factor 3B subunit 1, Splicing factor U2AF 65 kDa subunit | 著者 | Loerch, S, Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2021-10-27 | 公開日 | 2022-07-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing. J.Biol.Chem., 298, 2022
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5EV4
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3IIN
| Plasticity of the kink turn structural motif | 分子名称: | DNA/RNA (5'-R(*AP*AP*GP*CP*CP*AP*CP*AP*CP*AP*GP*AP*CP*C)-D(P*AP*GP*A)-R(P*CP*GP*GP*CP*C)-3'), DNA/RNA (5'-R(*CP*A)-D(P*T)-3'), Group I intron, ... | 著者 | Lipchock, S.V, Strobel, S.A, Antonioli, A.H, Cochrane, J.C. | 登録日 | 2009-08-02 | 公開日 | 2010-03-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (4.18 Å) | 主引用文献 | Plasticity of the RNA kink turn structural motif. Rna, 16, 2010
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4Y00
| Crystal Structure of Human TDP-43 RRM1 Domain with D169G Mutation in Complex with an Unmodified Single-stranded DNA | 分子名称: | DNA (5'-D(P*TP*TP*GP*AP*GP*CP*GP*T)-3'), TAR DNA-binding protein 43 | 著者 | Chiang, C.H, Kuo, P.H, Yang, W.Z, Yuan, H.S. | 登録日 | 2015-02-05 | 公開日 | 2016-02-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
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5DDR
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4Y0F
| Crystal Structure of Human TDP-43 RRM1 Domain in Complex with an Unmodified Single-stranded DNA | 分子名称: | DNA (5'-D(*GP*TP*TP*GP*AP*GP*CP*GP*TP*T)-3'), TAR DNA-binding protein 43 | 著者 | Chiang, C.H, Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yuan, H.S. | 登録日 | 2015-02-06 | 公開日 | 2016-02-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.648 Å) | 主引用文献 | Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation Sci Rep, 6, 2016
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3IWN
| Co-crystal structure of a bacterial c-di-GMP riboswitch | 分子名称: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), C-di-GMP riboswitch, U1 small nuclear ribonucleoprotein A | 著者 | Kulshina, N, Baird, N.J, Ferre-D'Amare, A.R. | 登録日 | 2009-09-02 | 公開日 | 2009-11-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Recognition of the bacterial second messenger cyclic diguanylate by its cognate riboswitch. Nat.Struct.Mol.Biol., 16, 2009
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4YOE
| Structure of UP1 bound to RNA 5'-AGU-3' | 分子名称: | ACETATE ION, Heterogeneous nuclear ribonucleoprotein A1, RNA AGU, ... | 著者 | Meagher, J.L, Stuckey, J.A. | 登録日 | 2015-03-11 | 公開日 | 2015-06-10 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | The First Crystal Structure of the UP1 Domain of hnRNP A1 Bound to RNA Reveals a New Look for an Old RNA Binding Protein. J.Mol.Biol., 427, 2015
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5GVQ
| Solution structure of the first RRM domain of human spliceosomal protein SF3b49 | 分子名称: | Splicing factor 3B subunit 4 | 著者 | Kuwasako, K, Nameki, N, Tsuda, K, Takahashi, M, Sato, A, Tochio, N, Inoue, M, Terada, T, Kigawa, T, Kobayashi, N, Shirouzu, M, Ito, T, Sakamoto, T, Wakamatsu, K, Guntert, P, Takahashi, S, Yokoyama, S, Muto, Y, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2016-09-06 | 公開日 | 2017-04-12 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the first RNA recognition motif domain of human spliceosomal protein SF3b49 and its mode of interaction with a SF3b145 fragment. Protein Sci., 26, 2017
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4YB1
| 20A Mutant c-di-GMP Vc2 Riboswitch bound with 3',3'-cGAMP | 分子名称: | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one, MAGNESIUM ION, RNA (91-MER), ... | 著者 | Ren, A.M, Patel, D.J, Rajashankar, R.K. | 登録日 | 2015-02-18 | 公開日 | 2015-04-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.081 Å) | 主引用文献 | Structural Basis for Molecular Discrimination by a 3',3'-cGAMP Sensing Riboswitch. Cell Rep, 11, 2015
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3K0J
| Crystal structure of the E. coli ThiM riboswitch in complex with thiamine pyrophosphate and the U1A crystallization module | 分子名称: | MAGNESIUM ION, RNA (87-MER), THIAMINE DIPHOSPHATE, ... | 著者 | Kulshina, N, Edwards, T.E, Ferre-D'Amare, A.R. | 登録日 | 2009-09-24 | 公開日 | 2009-12-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch. Rna, 16, 2010
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5EV1
| Structure I of Intact U2AF65 Recognizing a 3' Splice Site Signal | 分子名称: | DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*UP*UP*U)-D(P*UP*UP*(BRU)P*U)-R(P*UP*U)-3'), SODIUM ION, ... | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2015-11-19 | 公開日 | 2016-02-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.037 Å) | 主引用文献 | An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
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5EV2
| Structure II of Intact U2AF65 Recognizing the 3' Splice Site Signal | 分子名称: | 1,4-DIETHYLENE DIOXIDE, DI(HYDROXYETHYL)ETHER, DNA (5'-R(P*UP*U)-D(P*UP*U)-R(P*U)-D(P*UP*(BRU)P*U)-3'), ... | 著者 | Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L. | 登録日 | 2015-11-19 | 公開日 | 2016-02-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal. Nat Commun, 7, 2016
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5EV3
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4CH0
| RRM domain from C. elegans SUP-12 | 分子名称: | PROTEIN SUP-12, ISOFORM B | 著者 | Amrane, S, Mackereth, C.D. | 登録日 | 2013-11-27 | 公開日 | 2014-09-03 | 最終更新日 | 2016-05-04 | 実験手法 | SOLUTION NMR | 主引用文献 | Backbone-Independent Nucleic Acid Binding by Splicing Factor Sup-12 Reveals Key Aspects of Molecular Recognition Nat.Commun., 5, 2014
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4CIO
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4CH1
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4BS2
| NMR structure of human TDP-43 tandem RRMs in complex with UG-rich RNA | 分子名称: | 5'-R(*GP*UP*GP*UP*GP*AP*AP*UP*GP*AP*AP*UP)-3', TAR DNA-BINDING PROTEIN 43 | 著者 | Lukavsky, P.J, Daujotyte, D, Tollervey, J.R, Ule, J, Stuani, C, Buratti, E, Baralle, F.E, Damberger, F.F, Allain, F.H.T. | 登録日 | 2013-06-06 | 公開日 | 2013-11-13 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Basis of Ug-Rich RNA Recognition by the Human Splicing Factor Tdp-43 Nat.Struct.Mol.Biol., 20, 2013
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4ED5
| Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA | 分子名称: | 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ... | 著者 | Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X. | 登録日 | 2012-03-27 | 公開日 | 2012-05-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding. Acta Crystallogr.,Sect.D, 69, 2013
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6SR7
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6SXW
| Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638) | 分子名称: | SULFATE ION, Zinc finger protein 638 | 著者 | Newman, J.A, Aitkenhead, H, Wang, D, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Gileadi, O. | 登録日 | 2019-09-26 | 公開日 | 2019-10-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.751 Å) | 主引用文献 | Crystal structure of the first RRM domain of human Zinc finger protein 638 (ZNF638) To Be Published
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6SQQ
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6SQV
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