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5EV4

Structure IV of Intact U2AF65 Recognizing the 3' Splice Site Signal

Summary for 5EV4
Entry DOI10.2210/pdb5ev4/pdb
Related5EV1 5EV2 5EV3
DescriptorSplicing factor U2AF 65 kDa subunit, DNA/RNA (5'-R(P*UP*UP*UP*(UD)P*UP*U)-D(P*(BRU)P*(UD))-R(P*C)-3'), GLYCEROL, ... (4 entities in total)
Functional Keywordsprotein-rna complex, rna splicing factor, rna recognition motif, polypyrimidine tract, rna binding protein-rna complex, rna binding protein/rna
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains2
Total formula weight24802.55
Authors
Agrawal, A.A.,Jenkins, J.L.,Kielkopf, C.L. (deposition date: 2015-11-19, release date: 2016-02-24, Last modification date: 2024-03-06)
Primary citationAgrawal, A.A.,Salsi, E.,Chatrikhi, R.,Henderson, S.,Jenkins, J.L.,Green, M.R.,Ermolenko, D.N.,Kielkopf, C.L.
An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.
Nat Commun, 7:10950-10950, 2016
Cited by
PubMed: 26952537
DOI: 10.1038/ncomms10950
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.57 Å)
Structure validation

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