PDB: 657 件ウェブページステータス検索Chemie searchBIRD

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7SAA	Glycine and glutamate bound GluN1a-GluN2B NMDA receptors in non-active 1 conformation at 2.97 Angstrom resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... 著者 Chou, T.-H, Furukawa, H. 登録日 2021-09-22 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (2.97 Å) 主引用文献 Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAD	Memantine-bound GluN1a-GluN2B NMDA receptors 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glutamate receptor ionotropic, ... 著者 Chou, T.-H, Furukawa, H. 登録日 2021-09-22 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (3.96 Å) 主引用文献 Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7SAB	Phencyclidine-bound GluN1a-GluN2B NMDA receptors 分子名称: 1-(PHENYL-1-CYCLOHEXYL)PIPERIDINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Chou, T.-H, Furukawa, H. 登録日 2021-09-22 公開日 2022-07-20 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structural insights into binding of therapeutic channel blockers in NMDA receptors. Nat.Struct.Mol.Biol., 29, 2022
7TER	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (5.23 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEE	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 Non-active2-like 分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-04 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (6.59 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEB	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 non-active1-like 分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-04 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4.23 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TES	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TET	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (4.45 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TE9	Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1 分子名称: Fab2 heavy chain, Fab2 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-04 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (3.92 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
7TEQ	Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 active conformation 分子名称: Fab5 heavy chain, Fab5 light chain, Glutamate receptor ionotropic, ... 著者 Tajima, N, Furukawa, H. 登録日 2022-01-05 公開日 2022-03-02 実験手法 ELECTRON MICROSCOPY (7.51 Å) 主引用文献 Development and characterization of functional antibodies targeting NMDA receptors. Nat Commun, 13, 2022
3BFT	Structure of the ligand-binding core of GluR2 in complex with the agonist (S)-TDPA at 2.25 A resolution 分子名称: (2S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid, CACODYLATE ION, CHLORIDE ION, ... 著者 Beich-Frandsen, M, Mirza, O, Vestergaard, B, Gajhede, M, Kastrup, J.S. 登録日 2007-11-23 公開日 2008-10-28 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51, 2008
3B6T	Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686A Mutant in Complex with Quisqualate at 2.1 Resolution 分子名称: (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID, Glutamate receptor 2, SULFATE ION 著者 Cho, Y, Lolis, E, Howe, J.R. 登録日 2007-10-29 公開日 2008-02-05 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28, 2008
3B7D	Crystal structure of the GLUR2 ligand binding core (HS1S2J) in complex with CNQX at 2.5 A resolution 分子名称: 7-nitro-2,3-dioxo-2,3-dihydroquinoxaline-6-carbonitrile, Glutamate receptor 2 著者 Hays, F.A, Center for Structures of Membrane Proteins (CSMP) 登録日 2007-10-30 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists. Science, 318, 2007
3BBR	Crystal structure of the iGluR2 ligand binding core (S1S2J-N775S) in complex with a dimeric positive modulator as well as glutamate at 2.25 A resolution 分子名称: CHLORIDE ION, GLUTAMIC ACID, GLYCEROL, ... 著者 Kastrup, J.S, Gajhede, M. 登録日 2007-11-11 公開日 2007-12-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites Chem.Biol., 14, 2007
3B6Q	Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) Mutant T686A in Complex with Glutamate at 2.0 Resolution 分子名称: GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION 著者 Cho, Y, Lolis, E, Howe, J.R. 登録日 2007-10-29 公開日 2008-02-05 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28, 2008
3B6W	Crystal Structure of the GLUR2 Ligand Binding Core (S1S2J) T686S Mutant in Complex with Glutamate at 1.7 Resolution 分子名称: GLUTAMIC ACID, Glutamate receptor 2, SULFATE ION 著者 Cho, Y, Lolis, E, Howe, J.R. 登録日 2007-10-29 公開日 2008-02-05 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J.Neurosci., 28, 2008
3BFU	Structure of the ligand-binding core of GluR2 in complex with the agonist (R)-TDPA at 1.95 A resolution 分子名称: (2R)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propanoic acid, Glutamate receptor 2 著者 Beich-Frandsen, M, Mirza, O, Vestergaard, B, Gajhede, M, Kastrup, J.S. 登録日 2007-11-23 公開日 2008-10-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of the ligand-binding core of iGluR2 in complex with the agonists (R)- and (S)-2-amino-3-(4-hydroxy-1,2,5-thiadiazol-3-yl)propionic acid explain their unusual equipotency. J.Med.Chem., 51, 2008
3C33	Crystal structure of GluR5 ligand-binding core in complex with potassium at 1.78 Angstrom resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... 著者 Mayer, M.L. 登録日 2008-01-27 公開日 2008-06-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008
3C36	Crystal structure of GluR5 ligand-binding core in complex with ammonium ions at 1.68 Angstrom resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, AMMONIUM ION, CHLORIDE ION, ... 著者 Mayer, M.L. 登録日 2008-01-27 公開日 2008-06-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008
3C34	Crystal structure of GluR5 ligand-binding core in complex with rubidium at 1.82 Angstrom resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... 著者 Mayer, M.L. 登録日 2008-01-27 公開日 2008-06-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008
3C35	Crystal structure of GluR5 ligand-binding core in complex with cesium at 1.97 Angstrom resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CESIUM ION, CHLORIDE ION, ... 著者 Mayer, M.L. 登録日 2008-01-27 公開日 2008-06-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008
3C32	Crystal structure of GluR5 ligand-binding core in complex with sodium at 1.72 Angstrom resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... 著者 Mayer, M.L. 登録日 2008-01-27 公開日 2008-06-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008
3BKI	Crystal Structure of the GluR2 ligand binding core (S1S2J) in complex with FQX at 1.87 Angstroms 分子名称: Glutamate receptor 2, [1,2,5]oxadiazolo[3,4-g]quinoxaline-6,7(5H,8H)-dione 1-oxide 著者 Cruz, L, Estebanez-Perpina, E, Pfaff, S, Borngraeber, S, Bao, N, Fletterick, R, England, P. 登録日 2007-12-06 公開日 2008-09-16 最終更新日 2019-09-04 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 6-Azido-7-nitro-1,4-dihydroquinoxaline-2,3-dione (ANQX) forms an irreversible bond to the active site of the GluR2 AMPA receptor. J.Med.Chem., 51, 2008
3C31	Crystal structure of GluR5 ligand-binding core in complex with lithium at 1.49 Angstrom resolution 分子名称: 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE, CHLORIDE ION, GLUTAMATE RECEPTOR, ... 著者 Mayer, M.L. 登録日 2008-01-27 公開日 2008-06-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Molecular basis of kainate receptor modulation by sodium. Neuron, 58, 2008
4IO4	Crystal Structure of the AvGluR1 ligand binding domain complex with serine at 1.94 Angstrom resolution 分子名称: AvGluR1 ligand binding domain, CHLORIDE ION, GLYCEROL, ... 著者 Lomash, S, Chittori, S, Mayer, M.L. 登録日 2013-01-07 公開日 2013-02-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.941 Å) 主引用文献 Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels. Structure, 21, 2013

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