2ZP6
 
 | |
3AIY
 | | R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, REFINED AVERAGE STRUCTURE | | 分子名称: | PHENOL, PROTEIN (INSULIN) | | 著者 | O'Donoghue, S.I, Chang, X, Abseher, R, Nilges, M, Led, J.J. | | 登録日 | 1998-12-29 | | 公開日 | 2000-02-28 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Unraveling the symmetry ambiguity in a hexamer: calculation of the R6 human insulin structure.
J.Biomol.NMR, 16, 2000
|
|
3BXQ
 | | The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition | | 分子名称: | ZINC ION, insulin A chain, insulin B chain | | 著者 | Wan, Z.L, Huang, K, Hu, S.Q, Whittaker, J, Weiss, M.A. | | 登録日 | 2008-01-14 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The structure of a mutant insulin uncouples receptor binding from protein allostery. An electrostatic block to the TR transition.
J.Biol.Chem., 283, 2008
|
|
7Z5L
 | |
7Z5Q
 | |
6KH8
 | | Solution structure of Zn free Bovine Pancreatic Insulin in 20% acetic acid-d4 (pH 1.9) | | 分子名称: | Insulin A Chain, Insulin B chain | | 著者 | Bhunia, A, Ratha, B.N, Kar, R.K, Brender, J.R. | | 登録日 | 2019-07-14 | | 公開日 | 2020-10-07 | | 最終更新日 | 2020-11-18 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
|
|
6KH9
 | | Solution structure of bovine insulin amyloid intermediate-1 | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Ratha, B.N, Kar, R.K, Brender, J.B, Bhunia, A. | | 登録日 | 2019-07-14 | | 公開日 | 2020-08-12 | | 最終更新日 | 2020-11-18 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
|
|
6KHA
 | | Solution structure of bovine insulin amyloid intermediate-2 | | 分子名称: | Insulin A chain, Insulin B chain | | 著者 | Ratha, B.N, Kar, R.K, Brender, J.B, Bhunia, A. | | 登録日 | 2019-07-14 | | 公開日 | 2020-08-12 | | 最終更新日 | 2020-11-18 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution structure of a partially folded insulin aggregation intermediate.
Proteins, 88, 2020
|
|
6CK2
 | | Insulin analog containing a YB26W mutation | | 分子名称: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | | 著者 | Rege, N.K, Yee, V.C, Weiss, M.A. | | 登録日 | 2018-02-27 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure-based stabilization of insulin as a therapeutic protein assembly via enhanced aromatic-aromatic interactions.
J. Biol. Chem., 293, 2018
|
|
6X4X
 | | B24Y DKP insulin | | 分子名称: | Insulin, Insulin chain A | | 著者 | Weiss, M.A, Yang, Y. | | 登録日 | 2020-05-24 | | 公開日 | 2020-08-05 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Evolution of insulin at the edge of foldability and its medical implications.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3P2X
 | | Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2010-10-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
|
|
3P33
 | | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | | 登録日 | 2010-10-04 | | 公開日 | 2011-11-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
|
|
3Q6E
 | | Human insulin in complex with cucurbit[7]uril | | 分子名称: | Insulin A chain, Insulin B chain, cucurbit[7]uril | | 著者 | Chinai, J.M, Taylor, A.B, Hargreaves, N.D, Ryno, L.M, Morris, C.A, Hart, P.J, Urbach, A.R. | | 登録日 | 2010-12-31 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Molecular recognition of insulin by a synthetic receptor.
J.Am.Chem.Soc., 133, 2011
|
|
6Z7Y
 | |
6Z7Z
 | |
6Z7W
 | |
6ZHB
 | | 3D electron diffraction structure of bovine insulin | | 分子名称: | Insulin, ZINC ION | | 著者 | Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G, Ling, W.L, Abrahams, J.P. | | 登録日 | 2020-06-22 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (3.25 Å) | | 主引用文献 | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
3ROV
 | | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus | | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | | 著者 | Weiss, M.A, Wan, Z.L, Dodson, E.J, Liu, M, Xu, B, Hua, Q.X, Turkenburg, M, Whittingham, J, Nakagawa, S.H, Huang, K, Hu, S.Q, Jia, W.H, Wang, S.H, Brange, J, Whittaker, J, Arvan, P, Katsoyannis, P.G, Dodson, G.G. | | 登録日 | 2011-04-26 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
|
|
6ZI8
 | | X-ray diffraction structure of bovine insulin at 2.3 A resolution | | 分子名称: | CHLORIDE ION, Insulin, ZINC ION | | 著者 | Housset, D, Ling, W.L, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G. | | 登録日 | 2020-06-25 | | 公開日 | 2021-01-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
|
|
6O17
 | |
6NWV
 | |
3RTO
 | | Acoustically mounted porcine insulin microcrystals yield an X-ray SAD structure | | 分子名称: | Insulin, ZINC ION | | 著者 | Soares, A.S, Engel, M.A, Stearns, R, Datwani, S, Olechno, J, Ellson, R, Skinner, J.M, Allaire, M, Orville, A.M. | | 登録日 | 2011-05-03 | | 公開日 | 2011-05-18 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Acoustically Mounted Microcrystals Yield High-Resolution X-ray Structures.
Biochemistry, 50, 2011
|
|
6OR0
 | | Crystal structure of Insulin from Non-merohedrally twinned crystals | | 分子名称: | Insulin chain A, Insulin chain B | | 著者 | Sevvana, M, Ruf, M, Uson, I, Sheldrick, G.M, Herbst-Irmer, R. | | 登録日 | 2019-04-29 | | 公開日 | 2019-12-11 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Non-merohedral twinning: from minerals to proteins.
Acta Crystallogr D Struct Biol, 75, 2019
|
|
3T2A
 | | TMAO-grown cubic insulin (porcine) | | 分子名称: | Insulin A chain, Insulin B chain, trimethylamine oxide | | 著者 | Cahn, J, Venkat, M, Marshall, H, Juers, D. | | 登録日 | 2011-07-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2012-01-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The use of trimethylamine N-oxide as a primary precipitating agent and related methylamine osmolytes as cryoprotective agents for macromolecular crystallography.
Acta Crystallogr.,Sect.D, 68, 2012
|
|
6TC2
 | | Monoclinic human insulin in complex with p-coumaric acid | | 分子名称: | 4'-HYDROXYCINNAMIC ACID, Insulin, PHOSPHATE ION, ... | | 著者 | Triandafillidis, D.-P, Parthenios, N, Spiliopoulou, M, Valmas, A, Kosinas, C, Gozzo, F, Reinle-Schmitt, M, Beckers, D, Degen, T, Pop, M, Fitch, A, Wollenhaupt, J, Weiss, M.S, Karavassili, F, Margiolaki, I. | | 登録日 | 2019-11-04 | | 公開日 | 2020-11-11 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Insulin polymorphism induced by two polyphenols: new crystal forms and advances in macromolecular powder diffraction.
Acta Crystallogr D Struct Biol, 76, 2020
|
|
