4GBI
| Crystal structure of aspart insulin at pH 6.5 | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C. | Deposit date: | 2012-07-27 | Release date: | 2013-06-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.502 Å) | Cite: | A T3R3 hexamer of the human insulin variant B28Asp. Biophys.Chem., 173, 2013
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4GBL
| Crystal structure of aspart insulin at pH 8.5 | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Lima, L.M.T.R, Favero-Retto, M.P, Palmieri, L.C. | Deposit date: | 2012-07-27 | Release date: | 2013-06-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A T3R3 hexamer of the human insulin variant B28Asp. Biophys.Chem., 173, 2013
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4CY7
| Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II | Descriptor: | ACETATE ION, INSULIN A CHAIN, INSULIN B CHAIN, ... | Authors: | Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. | Deposit date: | 2014-04-10 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53, 2014
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4FG3
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4EX1
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-04-29 | Release date: | 2013-05-01 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.657 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EY9
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-01 | Release date: | 2013-05-01 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.471 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EYD
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-01 | Release date: | 2013-05-01 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.471 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4EWZ
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-04-29 | Release date: | 2013-05-01 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.791 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4F1C
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-06 | Release date: | 2013-05-08 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4F1B
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-06 | Release date: | 2013-05-08 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.591 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4F1G
| Human insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-06 | Release date: | 2013-05-08 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (1.637 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4FKA
| High resolution structure of the manganese derivative of insulin | Descriptor: | Insulin A chain, Insulin B chain, MANGANESE (II) ION, ... | Authors: | Prugovecki, B, Pulic, I, Toth, M, Matkovic-Calogovic, D. | Deposit date: | 2012-06-13 | Release date: | 2013-02-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.08 Å) | Cite: | High Resolution Structure of the Manganese Derivative of Insulin Croat.Chem.Acta, 85, 2012
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4E7T
| The structure of T6 bovine insulin | Descriptor: | Insulin A chain, Insulin B chain, ZINC ION | Authors: | Harris, P, Frankaer, C.G, Knudsen, M.V. | Deposit date: | 2012-03-19 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | The structures of T(6), T(3)R(3) and R(6) bovine insulin: combining X-ray diffraction and absorption spectroscopy. Acta Crystallogr.,Sect.D, 68, 2012
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4F4V
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-11 | Release date: | 2013-05-15 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (1.637 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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4F51
| Human Insulin | Descriptor: | CHLORIDE ION, Insulin A chain, Insulin B chain, ... | Authors: | Favero-Retto, M.P, Palmieri, L.C, Lima, L.M.T.R. | Deposit date: | 2012-05-11 | Release date: | 2013-05-15 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (1.637 Å) | Cite: | Structural meta-analysis of regular human insulin in pharmaceutical formulations. Eur J Pharm Biopharm, 85, 2013
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6VWI
| Head region of the closed conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain | Authors: | Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. | Deposit date: | 2020-02-19 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure, 28, 2020
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4XSS
| Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor, ... | Authors: | Lawrence, C, Kong, G.K.-W, Menting, J.G, Lawrence, M.C. | Deposit date: | 2015-01-22 | Release date: | 2015-06-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors. Structure, 23, 2015
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6VWG
| Head region of the open conformation of the human type 1 insulin-like growth factor receptor ectodomain in complex with human insulin-like growth factor II. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor II, Leucine-zippered human type 1 insulin-like growth factor receptor ectodomain | Authors: | Xu, Y, Kirk, N.S, Lawrence, M.C, Croll, T.I. | Deposit date: | 2020-02-19 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor. Structure, 28, 2020
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7WRQ
| Structure of Human IGF1/IGFBP3/ALS Ternary Complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin-like growth factor-binding protein 3, Insulin-like growth factor-binding protein complex acid labile subunit, ... | Authors: | Kim, H, Fu, Y, Kim, H.M. | Deposit date: | 2022-01-27 | Release date: | 2022-08-10 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex Nat Commun, 13, 2022
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7V3P
| Cryo-EM structure of the IGF1R/insulin complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin A chain, Insulin B chain, ... | Authors: | Zhang, J, Liu, C, Zhang, X, Wei, T, Wu, C. | Deposit date: | 2021-08-11 | Release date: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Cryo-EM structure of the IGF1R/insulin complex To Be Published
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1H59
| Complex of IGFBP-5 with IGF-I | Descriptor: | INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5, INSULIN-LIKE GROWTH FACTOR IA | Authors: | Zeslawski, W, Beisel, H.G, Kamionka, M, Kalus, W, Engh, R.A, Huber, R, Holak, T.A. | Deposit date: | 2001-05-21 | Release date: | 2002-05-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Interaction of Insulin-Like Growth Factor-I with the N-Terminal Domain of Igfbp-5 Embo J., 20, 2001
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7YRR
| Cryo-EM structure of IGF1R with two IGF1 complex | Descriptor: | Insulin-like growth factor 1 receptor, Isoform 3 of Insulin-like growth factor I | Authors: | Xi, Z, Cang, W. | Deposit date: | 2022-08-10 | Release date: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of IGF1R with two IGF1 complex at 4.3 angstroms resolution To Be Published
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6B70
| Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain and insulin | Descriptor: | FAB H11-E heavy chain, FAB H11-E light chain, Insulin, ... | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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7KD6
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6BFC
| Cryo-EM structure of human insulin degrading enzyme in complex with insulin | Descriptor: | Insulin, Insulin-degrading enzyme | Authors: | Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J. | Deposit date: | 2017-10-26 | Release date: | 2017-12-27 | Last modified: | 2021-04-28 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme. Elife, 7, 2018
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