4FG3

Crystal Structure Analysis of the Human Insulin

Summary for 4FG3

Related3I3Z
DescriptorInsulin, ZINC ION, CHLORIDE ION, ... (6 entities in total)
Functional Keywordspancreatic, hormone
Biological sourceHomo sapiens (human)
Cellular locationSecreted P01308 P01308
Total number of polymer chains4
Total molecular weight11929.12
Authors
Lima, L.M.T.R.,Favero-Retto, M.P. (deposition date: 2012-06-02, release date: 2013-06-12, Last modification date: 2017-11-15)
Primary citation
Favero-Retto, M.P.,Palmieri, L.C.,Souza, T.A.,Almeida, F.C.,Lima, L.M.
Structural meta-analysis of regular human insulin in pharmaceutical formulations.
Eur J Pharm Biopharm, 85:1112-1121, 2013
PubMed: 23692694 (PDB entries with the same primary citation)
DOI: 10.1016/j.ejpb.2013.05.005
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.001 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.262801.1%6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution