3I3Z

Human insulin

Summary for 3I3Z
Related3I40
DescriptorInsulin A chain, Insulin B chain (3 entities in total)
Functional Keywordsinsulin, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
Biological sourceHomo sapiens (human)
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Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight5787.63
Authors
Timofeev, V.I.,Bezuglov, V.V.,Miroshnikov, K.A.,Cuprov-Netochin, R.N.,Samigina, V.R.,Kuranova, I.P. (deposition date: 2009-07-01, release date: 2010-01-05, Last modification date: 2011-07-13)
Primary citationBezuglov, V.V.,Chuprov-Netochin, R.N.,Kuranova, I.P.,Miroshnikov, K.A.,Samigina, V.R.,Timofeev, V.I.
X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid.
Acta Crystallogr.,Sect.F, 66:259-263, 2010
PubMed: 20208155
DOI: 110.1107/S1744309110000461
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation
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PDB entries from 2021-06-23