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2L7M
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BU of 2l7m by Molmil
Solution Structure of the Pitx2 Homeodomain R24H mutant
Descriptor: Pituitary homeobox 2
Authors:Doerdelmann, T, Rance, M, Kojetin, D.J, Baird-Titus, J.M.
Deposit date:2010-12-14
Release date:2011-12-14
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of the Pitx2 Homeodomain R24H mutant
To be Published
2CUF
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BU of 2cuf by Molmil
Solution structure of the homeobox domain of the human hypothetical protein FLJ21616
Descriptor: FLJ21616 protein
Authors:Ohnishi, S, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-05-26
Release date:2005-11-26
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the homeobox domain of the human hypothetical protein FLJ21616
To be Published
2E1O
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BU of 2e1o by Molmil
Solution structure of RSGI RUH-028, a homeobox domain from human cDNA
Descriptor: Homeobox protein PRH
Authors:Nakamura, A, Ohnishi, S, Abe, T, Nameki, N, Tochio, N, Koshiba, S, Kigawa, T, Yokoyama, S, Kawaii, S, Hirota, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-10-27
Release date:2006-11-14
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of RSGI RUH-028, a homeobox domain from human cDNA
To be Published
2LD5
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BU of 2ld5 by Molmil
Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA
Descriptor: DNA (5'-D(*CP*AP*AP*AP*TP*AP*AP*AP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*TP*TP*TP*AP*TP*TP*TP*G)-3'), Homeobox protein Hox-A13
Authors:Zhang, Y.
Deposit date:2011-05-14
Release date:2011-08-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.
Plos One, 6, 2011
2DA1
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BU of 2da1 by Molmil
Solution structure of the first homeobox domain of AT-binding transcription factor 1 (ATBF1)
Descriptor: Alpha-fetoprotein enhancer binding protein
Authors:Ohnishi, S, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-13
Release date:2006-06-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the first homeobox domain of AT-binding transcription factor 1 (ATBF1)
To be Published
2L9R
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BU of 2l9r by Molmil
Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A
Descriptor: Homeobox protein Nkx-3.1
Authors:Liu, G, Xiao, R, Lee, H.-W, Hamilton, K, Ciccosanti, C, Wang, H.B, Acton, T.B, Everett, J.K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-02-22
Release date:2011-04-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A
To be Published
2DA2
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BU of 2da2 by Molmil
Solution structure of the second homeobox domain of AT-binding transcription factor 1 (ATBF1)
Descriptor: Alpha-fetoprotein enhancer binding protein
Authors:Ohnishi, S, Kigawa, T, Tochio, N, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2005-12-13
Release date:2006-06-13
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the second homeobox domain of AT-binding transcription factor 1 (ATBF1)
To be Published
2DMS
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BU of 2dms by Molmil
Solution structure of the homeobox domain of Homeobox protein OTX2
Descriptor: Homeobox protein OTX2
Authors:Ohnishi, S, Saito, K, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-24
Release date:2006-10-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the homeobox domain of Homeobox protein OTX2
To be Published
2DMQ
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BU of 2dmq by Molmil
Solution structure of the homeobox domain of LIM/homeobox protein Lhx9
Descriptor: LIM/homeobox protein Lhx9
Authors:Ohnishi, S, Tochio, N, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-24
Release date:2006-10-24
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Solution structure of the homeobox domain of LIM/homeobox protein Lhx9
To be Published
2M0C
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BU of 2m0c by Molmil
Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C
Descriptor: Homeobox protein aristaless-like 4
Authors:Xu, X, Eletsky, A, Pulavarti, S, Lee, D, Janjua, H, Xiao, R, Acton, T.B, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2012-10-24
Release date:2012-11-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution NMR Structure of Homeobox Domain of Human ALX4, Northeast Structural Genomics Consortium (NESG) Target HR4490C
To be Published
2KT0
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BU of 2kt0 by Molmil
Solution structure of human stem cell transcription factor Nanog homeodomain fragment
Descriptor: Homeobox protein NANOG
Authors:Sahu, S.C, Markley, J.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2010-01-15
Release date:2010-02-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Solution structure of human stem cell transcription factor Nanog
To be Published
3L1P
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BU of 3l1p by Molmil
POU protein:DNA complex
Descriptor: DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), POU domain, ...
Authors:Vahokoski, J, Groves, M.R, Pogenberg, V, Wilmanns, M.
Deposit date:2009-12-14
Release date:2010-12-15
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unique Oct4 interface is crucial for reprogramming to pluripotency
Nat.Cell Biol., 15, 2013
4CYC
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BU of 4cyc by Molmil
CRYSTAL STRUCTURE OF A UBX-EXD-DNA COMPLEX INCLUDING THE HEXAPEPTIDE AND UBDA MOTIFS
Descriptor: 5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*GP)-3', 5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*CP)-3', HOMEOBOX PROTEIN EXTRADENTICLE, ...
Authors:Foos, N, Mate, M.J, Ortiz-Lombardia, M.
Deposit date:2014-04-10
Release date:2015-02-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:A Flexible Extension of the Drosophila Ultrabithorax Homeodomain Defines a Novel Hox/Pbc Interaction Mode.
Structure, 23, 2015
5NO6
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BU of 5no6 by Molmil
TEAD4-HOXB13 complex bound to DNA
Descriptor: DNA, Homeobox protein Hox-B13, Transcriptional enhancer factor TEF-3
Authors:Morgunova, E, Jolma, A, Yin, Y, Popov, A, Taipale, J.
Deposit date:2017-04-11
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:TEAD4-HOXB13 complex bound to DNA
To Be Published
7XRC
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BU of 7xrc by Molmil
Crystal Structure of the dimeric Brn2 (Pou3f2) POU domain bound to palindromic MORE DNA
Descriptor: More palindromic Oct factor Recognition Element (MORE), POU domain protein
Authors:Tan, D.S.Y, Jauch, R.
Deposit date:2022-05-10
Release date:2022-06-15
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The homeodomain of Oct4 is a dimeric binder of methylated CpG elements.
Nucleic Acids Res., 51, 2023
6HT5
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BU of 6ht5 by Molmil
Oct4/Sox2:UTF1 structure
Descriptor: DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3'), POU domain, ...
Authors:Vahokoski, J, Meusch, D, Groves, M, Pogenberg, V, Wilmanns, M.
Deposit date:2018-10-03
Release date:2019-10-23
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.451 Å)
Cite:Oct4/Sox2:UTF1 structure
To Be Published
6WC5
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BU of 6wc5 by Molmil
Crystal Structure of a Ternary MEF2B/NKX2-5/myocardin enhancer DNA Complex
Descriptor: Homeobox protein Nkx-2.5, Myocardin enhancer DNA, Myocyte-specific enhancer factor 2B
Authors:Chen, L, Lei, X.
Deposit date:2020-03-29
Release date:2020-07-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
6WC2
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BU of 6wc2 by Molmil
Crystal Structure of a Ternary MEF2 Chimera/NKX2-5/myocardin enhancer DNA Complex
Descriptor: Homeobox protein Nkx-2.5, MEF2 Chimera,Myocyte-specific enhancer factor 2B,Myocyte-specific enhancer factor 2A, Myocardin Enhancer DNA
Authors:Lei, X, Chen, L.
Deposit date:2020-03-29
Release date:2020-07-22
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Ternary Complexes of MEF2 and NKX2-5 Bound to DNA Reveal a Disease Related Protein-Protein Interaction Interface.
J.Mol.Biol., 432, 2020
1MH3
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BU of 1mh3 by Molmil
maltose binding-a1 homeodomain protein chimera, crystal form I
Descriptor: maltose binding-a1 homeodomain protein chimera
Authors:Ke, A, Wolberger, C.
Deposit date:2002-08-19
Release date:2002-09-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Insights into binding cooperativity of MATa1/MATalpha2 from the crystal structure of a MATa1 homeodomain-maltose binding protein chimera
Protein Sci., 12, 2003
1MNM
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BU of 1mnm by Molmil
YEAST MATALPHA2/MCM1/DNA TERNARY TRANSCRIPTION COMPLEX CRYSTAL STRUCTURE
Descriptor: DNA (STE6 OPERATOR DNA), PROTEIN (MAT ALPHA-2 TRANSCRIPTIONAL REPRESSOR), PROTEIN (MCM1 TRANSCRIPTIONAL REGULATOR)
Authors:Tan, S, Richmond, T.J.
Deposit date:1997-11-03
Release date:1998-03-18
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of the yeast MATalpha2/MCM1/DNA ternary complex.
Nature, 391, 1998
6YOV
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BU of 6yov by Molmil
OCT4-SOX2-bound nucleosome - SHL+6
Descriptor: DNA (142-MER), Green fluorescent protein,POU domain, class 5, ...
Authors:Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
Deposit date:2020-04-15
Release date:2020-05-06
Last modified:2020-07-08
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020
3D1N
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BU of 3d1n by Molmil
Structure of human Brn-5 transcription factor in complex with corticotrophin-releasing hormone gene promoter
Descriptor: 5'-D(*DAP*DGP*DCP*DAP*DTP*DAP*DAP*DAP*DTP*DAP*DAP*DTP*DAP*DA)-3', 5'-D(*DTP*DTP*DAP*DTP*DTP*DAP*DTP*DTP*DTP*DAP*DTP*DGP*DCP*DT)-3', POU domain, ...
Authors:Pereira, J.H, Ha, S.C, Kim, S.-H.
Deposit date:2008-05-06
Release date:2009-05-26
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of human Brn-5 transcription factor in complex with CRH gene promoter.
J.Struct.Biol., 167, 2009
7U0G
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BU of 7u0g by Molmil
structure of LIN28b nucleosome bound 3 OCT4
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Lian, T, Guan, R, Bai, Y.
Deposit date:2022-02-18
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
7U0I
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BU of 7u0i by Molmil
Structure of LIN28b nucleosome bound 2 OCT4
Descriptor: DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ...
Authors:Tengfei, L, Guan, R, Bai, Y.
Deposit date:2022-02-18
Release date:2023-06-28
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
6T90
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BU of 6t90 by Molmil
OCT4-SOX2-bound nucleosome - SHL-6
Descriptor: DNA (146-MER), Green fluorescent protein,POU domain, class 5, ...
Authors:Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H.
Deposit date:2019-10-25
Release date:2020-05-06
Last modified:2020-07-08
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Mechanisms of OCT4-SOX2 motif readout on nucleosomes.
Science, 368, 2020

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