PDB: 291 件ウェブページステータス検索Chemie searchBIRD

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6E2F	Cryo-EM structure of human TRPV6 in complex with Calmodulin 分子名称: CALCIUM ION, Calmodulin-1, Transient receptor potential cation channel subfamily V member 6 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2018-07-11 公開日 2018-08-22 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6. Sci Adv, 4, 2018
8GVX	Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class2 分子名称: (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... 著者 Won, J, Jeong, H, Lee, H.H. 登録日 2022-09-16 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
7X6I	Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class1 分子名称: (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... 著者 Won, J, Jeong, H, Lee, H.H. 登録日 2022-03-07 公開日 2023-04-26 最終更新日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3.93 Å) 主引用文献 Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
8JKM	RN-1747 bound state of mTRPV4 分子名称: Transient receptor potential cation channel subfamily V member 4 著者 Zhen, W.X, Yang, F. 登録日 2023-06-01 公開日 2023-12-13 実験手法 ELECTRON MICROSCOPY (3.98 Å) 主引用文献 Structural basis of ligand activation and inhibition in a mammalian TRPV4 ion channel. Cell Discov, 9, 2023
7RAU	Structure of TRPV3 in complex with osthole 分子名称: 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, Transient receptor potential cation channel subfamily V member 3 著者 Neuberger, A, Nadezhdin, K.D, Sobolevsky, A.I. 登録日 2021-07-02 公開日 2021-09-08 最終更新日 2021-11-17 実験手法 ELECTRON MICROSCOPY (3.99 Å) 主引用文献 Structural mechanism of TRPV3 channel inhibition by the plant-derived coumarin osthole. Embo Rep., 22, 2021
6DMU	PI(4,5)P2 bound full-length rbTRPV5 分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate 著者 Hughes, T.E.T, Pumroy, R.A, Moiseenkova-Bell, V.Y. 登録日 2018-06-05 公開日 2018-10-24 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural insights on TRPV5 gating by endogenous modulators. Nat Commun, 9, 2018
6DVY	Cryo-EM structure of mouse TRPV3 in complex with 2-Aminoethoxydiphenyl borate (2-APB) 分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2018-06-25 公開日 2018-09-05 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure and gating mechanism of the transient receptor potential channel TRPV3. Nat. Struct. Mol. Biol., 25, 2018
6MHX	Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (2) 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. 登録日 2018-09-18 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
6MHW	Structure of human TRPV3 in the presence of 2-APB in C2 symmetry (1) 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Zubcevic, L, Herzik, M.A, Wu, M, Borschel, W.F, Hirschi, M, Song, A, Lander, G.C, Lee, S.Y. 登録日 2018-09-18 公開日 2018-10-03 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Conformational ensemble of the human TRPV3 ion channel. Nat Commun, 9, 2018
6BO9	Cryo-EM structure of human TRPV6 in amphipols 分子名称: Transient receptor potential cation channel subfamily V member 6 著者 McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I. 登録日 2017-11-18 公開日 2017-12-20 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Opening of the human epithelial calcium channel TRPV6. Nature, 553, 2018
6UW8	Cryo-EM structure of the human TRPV3 K169A mutant briefly exposed to 2-APB for 3 minutes, determined in lipid nanodisc 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Deng, Z, Yuan, P. 登録日 2019-11-04 公開日 2020-07-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.02 Å) 主引用文献 Gating of human TRPV3 in a lipid bilayer. Nat.Struct.Mol.Biol., 27, 2020
6PVN	Cryo-EM structure of mouse TRPV3-Y564A in putative sensitized state at 4 degrees Celsius 分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 3 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2019-07-21 公開日 2019-10-23 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.07 Å) 主引用文献 Structural basis of temperature sensation by the TRP channel TRPV3. Nat.Struct.Mol.Biol., 26, 2019
6OT2	Structure of the TRPV3 K169A sensitized mutant in apo form at 4.1 A resolution 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Zubcevic, L, Borschel, W.F, Hsu, A.L, Borgnia, M.J, Lee, S.-Y. 登録日 2019-05-02 公開日 2019-05-22 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Regulatory switch at the cytoplasmic interface controls TRPV channel gating. Elife, 8, 2019
7AA5	Human TRPV4 structure in presence of 4a-PDD 分子名称: CALCIUM ION, Transient receptor potential cation channel subfamily V member 4,Green fluorescent protein 著者 Botte, M, Ulrich, A.K.G, Adaixo, R, Gnutt, D, Brockmann, A, Bucher, D, Chami, M, Bocquet, M, Ebbinghaus-Kintscher, U, Puetter, V, Becker, A, Egner, U, Stahlberg, H, Hennig, M, Holton, S.J. 登録日 2020-09-03 公開日 2021-08-18 実験手法 ELECTRON MICROSCOPY (4.18 Å) 主引用文献 Cryo-EM structural studies of the agonist complexed human TRPV4 ion-channel reveals novel structural rearrangements resulting in an open-conformation To Be Published
6PBF	ZINC9155420-bound TRPV5 in nanodiscs 分子名称: (1S)-1-(4-oxo-5-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)ethyl [(2S)-3-oxo-3,4-dihydro-2H-1,4-benzothiazin-2-yl]acetate, Transient receptor potential cation channel subfamily V member 5 著者 Hughes, T.E.T, Rosario, J.S.D, Kapoor, A, Yazici, A.T, Fluck, E.C, Filizola, M, Rohacs, T, Moiseenkova-Bell, V.Y. 登録日 2019-06-13 公開日 2019-11-06 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure-based characterization of novel TRPV5 inhibitors. Elife, 8, 2019
3J5R	Reconstruction of TRPV1 ion channel in complex with capsaicin by single particle cryo-microscopy 分子名称: Transient receptor potential cation channel subfamily V member 1 著者 Liao, M, Cao, E, Julius, D, Cheng, Y. 登録日 2013-10-28 公開日 2013-12-04 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 TRPV1 structures in distinct conformations reveal activation mechanisms. Nature, 504, 2013
6BOA	Cryo-EM structure of human TRPV6-R470E in amphipols 分子名称: Transient receptor potential cation channel subfamily V member 6 著者 McGoldrick, L.L, Singh, A.K, Saotome, K, Yelshanskaya, M.V, Twomey, E.C, Grassucci, R.A, Sobolevsky, A.I. 登録日 2017-11-18 公開日 2017-12-20 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Opening of the human epithelial calcium channel TRPV6. Nature, 553, 2018
6DVZ	Cryo-EM structure of mouse TRPV3-Y564A in complex with 2-Aminoethoxydiphenyl borate (2-APB) 分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 3 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2018-06-25 公開日 2018-09-05 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Structure and gating mechanism of the transient receptor potential channel TRPV3. Nat. Struct. Mol. Biol., 25, 2018
3J9P	Structure of the TRPA1 ion channel determined by electron cryo-microscopy 分子名称: Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera 著者 Paulsen, C.E, Armache, J.-P, Gao, Y, Cheng, Y, Julius, D. 登録日 2015-02-14 公開日 2015-04-08 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.24 Å) 主引用文献 Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature, 520, 2015
6DVW	Cryo-EM structure of mouse TRPV3 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2018-06-25 公開日 2018-09-05 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure and gating mechanism of the transient receptor potential channel TRPV3. Nat. Struct. Mol. Biol., 25, 2018
6UW9	Cryo-EM structure of the human TRPV3 K169A mutant in the presence of 2-APB, determined in lipid nanodisc 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Deng, Z, Yuan, P. 登録日 2019-11-04 公開日 2020-07-01 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.33 Å) 主引用文献 Gating of human TRPV3 in a lipid bilayer. Nat.Struct.Mol.Biol., 27, 2020
6D7S	Cryo-EM structure of human TRPV6-Y467A in amphipols 分子名称: Transient receptor potential cation channel subfamily V member 6 著者 Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2018-04-25 公開日 2018-07-18 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.34 Å) 主引用文献 Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB. Nat Commun, 9, 2018
7K4E	Cryo-EM structure of human TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor 30 分子名称: 5-({4-[(1R,4S)-3'-methyl[1,2,3,4-tetrahydro[1,1'-biphenyl]]-4-yl]piperazin-1-yl}methyl)pyridin-2(1H)-one, Transient receptor potential cation channel subfamily V member 6 著者 Neuberger, A, Nadezhdin, K.D, Singh, A.K, Sobolevsky, A.I. 登録日 2020-09-15 公開日 2020-12-09 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.34 Å) 主引用文献 Inactivation-mimicking block of the epithelial calcium channel TRPV6. Sci Adv, 6, 2020
8GKG	Human TRPV3 pentamer structure 分子名称: Transient receptor potential cation channel subfamily V member 3 著者 Lansky, S, Betancourt, J.M, Scheuring, S. 登録日 2023-03-18 公開日 2023-09-06 最終更新日 2023-09-20 実験手法 ELECTRON MICROSCOPY (4.38 Å) 主引用文献 A pentameric TRPV3 channel with a dilated pore. Nature, 621, 2023
6PVL	Cryo-EM structure of mouse TRPV3 in closed state at 42 degrees Celsius 分子名称: SODIUM ION, Transient receptor potential cation channel subfamily V member 3 著者 Singh, A.K, McGoldrick, L.L, Sobolevsky, A.I. 登録日 2019-07-21 公開日 2019-10-23 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural basis of temperature sensation by the TRP channel TRPV3. Nat.Struct.Mol.Biol., 26, 2019

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