PDB: 522 件ウェブページステータス検索Chemie searchBIRD

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7CSP	Structure of Ephexin4 IDPSH 分子名称: Rho guanine nucleotide exchange factor 16 著者 Zhang, M, Lin, L, Wang, C, Zhu, J. 登録日 2020-08-15 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
7CSR	Structure of Ephexin4 R676L 分子名称: Rho guanine nucleotide exchange factor 16 著者 Zhang, M, Lin, L, Wang, C, Zhu, J. 登録日 2020-08-17 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
7CSO	Structure of Ephexin4 DH-PH-SH3 分子名称: Rho guanine nucleotide exchange factor 16, SULFATE ION 著者 Zhang, M, Lin, L, Wang, C, Zhu, J. 登録日 2020-08-15 公開日 2021-02-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Double inhibition and activation mechanisms of Ephexin family RhoGEFs. Proc.Natl.Acad.Sci.USA, 118, 2021
7D7S	HIV-1 SF2 Nef in complex with the Fyn SH3 R96I mutant 分子名称: Protein Nef, Tyrosine-protein kinase Fyn 著者 Aldehaiman, A, Shahul Hamed, U.F, Arold, S.T. 登録日 2020-10-05 公開日 2020-11-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.32 Å) 主引用文献 Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
7DPA	Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex 分子名称: Dedicator of cytokinesis protein 5, Engulfment and cell motility protein 1, Ras-related C3 botulinum toxin substrate 1 著者 Kukimoto-Niino, M, Katsura, K, Kaushik, R, Ehara, H, Yokoyama, T, Uchikubo-Kamo, T, Mishima-Tsumagari, C, Yonemochi, M, Ikeda, M, Hanada, K, Zhang, K.Y.J, Shirouzu, M. 登録日 2020-12-18 公開日 2021-08-04 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex. Sci Adv, 7, 2021
8F2P	Nef SF2 dimerization mutant bound to Hck SH3 分子名称: C-terminal core protein, Tyrosine-protein kinase HCK 著者 Thomas, C.E, Alvarado, J.J, Smithgall, T.E. 登録日 2022-11-08 公開日 2023-02-22 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Neutron Reflectometry and Molecular Simulations Demonstrate HIV-1 Nef Homodimer Formation on Model Lipid Bilayers. J.Mol.Biol., 435, 2023
6UY7	Crystal structure of the STAC3 tandem SH3 domains - P269R 分子名称: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3 著者 Rufenach, B, Van Petegem, F. 登録日 2019-11-12 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.105 Å) 主引用文献 Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling. Structure, 28, 2020
6UY9	Crystal structure of the STAC3 tandem SH3 domains - P269R, W284S 分子名称: 1,2-ETHANEDIOL, SH3 and cysteine-rich domain-containing protein 3, SODIUM ION 著者 Rufenach, B, Van Petegem, F. 登録日 2019-11-12 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling. Structure, 28, 2020
6UY8	Crystal structure of the STAC3 tandem SH3 domains - P269R, K329N 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SH3 and cysteine-rich domain-containing protein 3 著者 Rufenach, B, Van Petegem, F. 登録日 2019-11-12 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.649 Å) 主引用文献 Multiple Sequence Variants in STAC3 Affect Interactions with CaV1.1 and Excitation-Contraction Coupling. Structure, 28, 2020
3JV3	Structure of SH3E-DH unit of murine intersectin-1L 分子名称: Intersectin-1 著者 Ahmad, K.F. 登録日 2009-09-15 公開日 2010-07-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The minimal autoinhibited unit of the guanine nucleotide exchange factor intersectin. Plos One, 5, 2010
5YPR	Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor 分子名称: Disks large homolog 4, Synthesized GK inhibitor 著者 Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M. 登録日 2017-11-02 公開日 2018-03-14 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs. Cell Rep, 21, 2017
3NMZ	Crystal structure of APC complexed with Asef 分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4 著者 Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. 登録日 2010-06-23 公開日 2011-07-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structural basis for the recognition of Asef by adenomatous polyposis coli. Cell Res., 22, 2012
6B25	Crystal structure of human STAC1 Tandem SH3 Domains (288-402) 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SH3 and cysteine-rich domain-containing protein 著者 Wong King Yuen, S.M, Van Petegem, F. 登録日 2017-09-19 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Structural insights into binding of STAC proteins to voltage-gated calcium channels. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4A63	Crystal structure of the p73-ASPP2 complex at 2.6A resolution 分子名称: ACETATE ION, APOPTOSIS STIMULATING OF P53 PROTEIN 2, TUMOUR PROTEIN 73, ... 著者 Canning, P, Sharpe, T, Krojer, T, Savitsky, P, Cooper, C.D.O, Salah, E, Keates, T, Muniz, J, Vollmar, M, von Delft, F, Weigelt, J, Arrowsmith, C, Bountra, C, Edwards, A, Bullock, A.N. 登録日 2011-10-31 公開日 2011-12-21 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73. J.Mol.Biol., 423, 2012
3REB	HIV-1 Nef protein in complex with engineered Hck-SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK 著者 Schulte, A, Blankenfeldt, W, Geyer, M. 登録日 2011-04-04 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS ONE, 6, 2011
3RBB	HIV-1 NEF protein in complex with engineered HCK SH3 domain 分子名称: 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK 著者 Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M. 登録日 2011-03-29 公開日 2011-04-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly. Traffic, 12, 2011
3REA	HIV-1 Nef protein in complex with engineered Hck-SH3 domain 分子名称: Protein Nef, Tyrosine-protein kinase HCK 著者 Schulte, A, Blankenfeldt, W, Geyer, M. 登録日 2011-04-04 公開日 2011-06-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef. PLoS ONE, 6, 2011
3UAT	Guanylate Kinase Domains of the MAGUK Family Scaffold Proteins as Specific Phospho-Protein Binding Modules 分子名称: Disks large homolog 1, phosphor-LGN peptide 著者 Shang, Y, Zhu, J, Wen, W, Zhang, M. 登録日 2011-10-22 公開日 2011-12-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules Embo J., 2011
3TVT	Structural basis for Discs Large interaction with Pins 分子名称: Disks large 1 tumor suppressor protein, Partner of Inscuteable 著者 Johnston, C.A, Doe, C.Q, Prehoda, K.E. 登録日 2011-09-20 公開日 2012-08-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural basis for Discs Large interaction with Pins To be Published
7SJ4	Human Trio residues 1284-1959 in complex with Rac1 分子名称: Ras-related C3 botulinum toxin substrate 1, Triple functional domain protein 著者 Chen, C.-L, Ravala, S.K, Bandekar, S.J, Cash, J, Tesmer, J.J.G. 登録日 2021-10-15 公開日 2022-07-06 最終更新日 2022-08-24 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1. J.Biol.Chem., 298, 2022
4D8D	Crystal structure of HIV-1 NEF Fyn-SH3 R96W variant 分子名称: GLYCEROL, Protein Nef, Tyrosine-protein kinase Fyn 著者 Arold, S.T, Hoh, F, Dumas, C. 登録日 2012-01-10 公開日 2013-01-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5201 Å) 主引用文献 Synergy and allostery in ligand binding by HIV-1 Nef. Biochem.J., 478, 2021
3EHQ	Crystal Structure of Human Osteoclast Stimulating Factor 分子名称: 1,2-ETHANEDIOL, Osteoclast-stimulating factor 1 著者 Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. 登録日 2008-09-14 公開日 2009-08-04 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
3EHR	Crystal Structure of Human Osteoclast Stimulating Factor 分子名称: Osteoclast-stimulating factor 1 著者 Tong, S, Zhou, H, Gao, Y, Zhu, Z, Zhang, X, Teng, M, Niu, L. 登録日 2008-09-14 公開日 2009-08-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of human osteoclast stimulating factor Proteins, 75, 2009
5FUL	Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with SAH 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. 登録日 2016-01-27 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors. FEBS J., 284, 2017
5FWA	Crystal Structure of Mus musculus Protein Arginine Methyltransferase 2 with CP1 分子名称: 1,2-ETHANEDIOL, 9-(6-carbamimidamido-5,6-dideoxy-beta-D-ribo-hexofuranosyl)-9H-purin-6-amine, CALCIUM ION, ... 著者 Cura, V, Troffer-Charlier, N, Marechal, N, Bonnefond, L, Cavarelli, J. 登録日 2016-02-16 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors. FEBS J., 284, 2017

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