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6TEJ
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BU of 6tej by Molmil
Structure of apo IrtAB devoid SID in complex with sybody Syb_NL5
Descriptor: DECYL-BETA-D-MALTOPYRANOSIDE, Drug ABC transporter ATP-binding protein, NICKEL (II) ION, ...
Authors:Gonda, I, Arnold, F.M, Hutter, C.A.J, Weber, M.S, Seeger, M.A, Hurlimann, L.M.
Deposit date:2019-11-12
Release date:2020-04-01
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The ABC exporter IrtAB imports and reduces mycobacterial siderophores.
Nature, 580, 2020
6TQE
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BU of 6tqe by Molmil
The structure of ABC transporter Rv1819c without addition of substrate
Descriptor: ABC transporter ATP-binding protein/permease, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Rempel, S, Gati, C, Slotboom, D.J, Guskov, A.
Deposit date:2019-12-16
Release date:2020-04-01
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds.
Nature, 580, 2020
6TMF
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BU of 6tmf by Molmil
Structure of an archaeal ABCE1-bound ribosomal post-splitting complex
Descriptor: 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Kratzat, H, Becker, T, Tampe, R, Beckmann, R.
Deposit date:2019-12-04
Release date:2020-02-12
Last modified:2020-05-13
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Molecular analysis of the ribosome recycling factor ABCE1 bound to the 30S post-splitting complex.
Embo J., 39, 2020
6UJT
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BU of 6ujt by Molmil
P-glycoprotein mutant-Y303A and C952A-with BDE100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
Authors:Aller, S.G, Le, C.A.
Deposit date:2019-10-03
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.17 Å)
Cite:Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJR
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BU of 6ujr by Molmil
P-glycoprotein mutant-F724A and C952A-with BDE100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
Authors:Aller, S.G, Le, C.A.
Deposit date:2019-10-03
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJW
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BU of 6ujw by Molmil
P-glycoprotein mutant-Y306A and C952A-with BDE100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
Authors:Aller, S.G, Le, C.A.
Deposit date:2019-10-03
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.15 Å)
Cite:Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJP
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BU of 6ujp by Molmil
P-glycoprotein mutant-F979A and C952A-with BDE100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
Authors:Aller, S.G, Le, C.A.
Deposit date:2019-10-03
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.98 Å)
Cite:Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJS
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BU of 6ujs by Molmil
P-glycoprotein mutant-F728A and C952A-with BDE100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
Authors:Aller, S.G, Le, C.A.
Deposit date:2019-10-03
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.17 Å)
Cite:Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6UJN
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BU of 6ujn by Molmil
P-glycoprotein mutant-C952A-with BDE100
Descriptor: 2,4-dibromophenyl 2,4,6-tribromophenyl ether, ATP-dependent translocase ABCB1
Authors:Aller, S.G, Le, C.A.
Deposit date:2019-10-03
Release date:2020-05-27
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.98 Å)
Cite:Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein.
Iucrj, 7, 2020
6V9Z
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BU of 6v9z by Molmil
Cryo-EM structure of PCAT1 bound to its CtA peptide substrate
Descriptor: ABC-type bacteriocin transporter, CtA
Authors:Kieuvongngam, V, Oldham, M.L, Chen, J.
Deposit date:2019-12-16
Release date:2020-01-22
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Structural basis of substrate recognition by a polypeptide processing and secretion transporter.
Elife, 9, 2020
6UY0
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BU of 6uy0 by Molmil
Cryo-EM structure of wild-type bovine multidrug resistance protein 1 (MRP1) under active turnover conditions
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, CHOLESTEROL, ...
Authors:Johnson, Z.L, Chen, J.
Deposit date:2019-11-09
Release date:2020-06-10
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Characterization of the kinetic cycle of an ABC transporter by single-molecule and cryo-EM analyses.
Elife, 9, 2020
6UZL
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BU of 6uzl by Molmil
Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 2
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F.
Deposit date:2019-11-15
Release date:2020-03-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
6UZ2
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BU of 6uz2 by Molmil
Cryo-EM structure of nucleotide-free MsbA reconstituted into peptidiscs, conformation 1
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Angiulli, G, Walz, T, Dhupar, H.S, Suzuki, H, Wason, I.S, Duong Van Hoa, F.
Deposit date:2019-11-14
Release date:2020-03-04
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:New approach for membrane protein reconstitution into peptidiscs and basis for their adaptability to different proteins.
Elife, 9, 2020
6VQU
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BU of 6vqu by Molmil
Structure of a bacterial Atm1-family ABC exporter
Descriptor: ATM1-type heavy metal exporter
Authors:Fan, C, Rees, D.C.
Deposit date:2020-02-05
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.88 Å)
Cite:A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VXF
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BU of 6vxf by Molmil
Structure of apo-closed ABCG2
Descriptor: Broad substrate specificity ATP-binding cassette transporter ABCG2
Authors:Orlando, B.J, Maofu, L.
Deposit date:2020-02-21
Release date:2020-05-13
Last modified:2020-05-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
6VQT
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BU of 6vqt by Molmil
Structure of a bacterial Atm1-family ABC exporter with MgADPVO4 bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATM1-type heavy metal exporter, MAGNESIUM ION, ...
Authors:Fan, C, Rees, D.C.
Deposit date:2020-02-05
Release date:2020-07-29
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:A structural framework for unidirectional transport by a bacterial ABC exporter.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VXJ
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BU of 6vxj by Molmil
Structure of ABCG2 bound to SN38
Descriptor: 7-ethyl-10-hydroxycamptothecin, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL
Authors:Orlando, B.J, Liao, M.
Deposit date:2020-02-22
Release date:2020-05-13
Last modified:2020-05-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
6VXH
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BU of 6vxh by Molmil
Structure of ABCG2 bound to imatinib
Descriptor: 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL
Authors:Orlando, B.J, Liao, M.
Deposit date:2020-02-21
Release date:2020-05-13
Last modified:2020-05-20
Method:ELECTRON MICROSCOPY (4 Å)
Cite:ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
6VXI
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BU of 6vxi by Molmil
Structure of ABCG2 bound to mitoxantrone
Descriptor: 1,4-DIHYDROXY-5,8-BIS({2-[(2-HYDROXYETHYL)AMINO]ETHYL}AMINO)-9,10-ANTHRACENEDIONE, Broad substrate specificity ATP-binding cassette transporter ABCG2, CHOLESTEROL
Authors:Orlando, B.J, Liao, M.
Deposit date:2020-02-21
Release date:2020-05-13
Last modified:2020-05-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:ABCG2 transports anticancer drugs via a closed-to-open switch.
Nat Commun, 11, 2020
5UAK
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BU of 5uak by Molmil
Dephosphorylated, ATP-free human cystic fibrosis transmembrane conductance regulator (CFTR)
Descriptor: Cystic fibrosis transmembrane conductance regulator
Authors:Liu, F, Zhang, Z, Chen, J.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.87 Å)
Cite:Molecular Structure of the Human CFTR Ion Channel.
Cell, 169, 2017
5TV4
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BU of 5tv4 by Molmil
3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc
Descriptor: 3-HYDROXY-TETRADECANOIC ACID, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, LAURIC ACID, ...
Authors:Mi, W, Walz, T, Liao, M.
Deposit date:2016-11-08
Release date:2017-09-20
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
5TTP
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BU of 5ttp by Molmil
Cryo-EM structure of MsbA-nanodisc with ADP-vanadate
Descriptor: Lipid A export ATP-binding/permease protein MsbA
Authors:Mi, W, Walz, T, Liao, M.
Deposit date:2016-11-04
Release date:2017-09-20
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
5U1D
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BU of 5u1d by Molmil
Cryo-EM structure of the human TAP ATP-Binding Cassette Transporter
Descriptor: Antigen peptide transporter 1, Antigen peptide transporter 2, TAP transporter inhibitor ICP47
Authors:Oldham, M.L, Chen, J, Grigorieff, N.
Deposit date:2016-11-28
Release date:2017-01-11
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.97 Å)
Cite:Structure of the transporter associated with antigen processing trapped by herpes simplex virus.
Elife, 5, 2016
5TWV
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BU of 5twv by Molmil
Cryo-EM structure of the pancreatic ATP-sensitive K+ channel SUR1/Kir6.2 in the presence of ATP and glibenclamide
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 8, ATP-sensitive inward rectifier potassium channel 11
Authors:Martin, G.M, Yoshioka, C, Chen, J.Z, Shyng, S.L.
Deposit date:2016-11-14
Release date:2017-01-25
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (6.3 Å)
Cite:Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.
Elife, 6, 2017
5UAR
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BU of 5uar by Molmil
Dephosphorylated, ATP-free cystic fibrosis transmembrane conductance regulator (CFTR) from zebrafish
Descriptor: Cystic fibrosis transmembrane conductance regulator, DECANE
Authors:Zhang, Z, Chen, J.
Deposit date:2016-12-19
Release date:2017-01-18
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Atomic Structure of the Cystic Fibrosis Transmembrane Conductance Regulator.
Cell, 167, 2016

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