6UJW
P-glycoprotein mutant-Y306A and C952A-with BDE100
Summary for 6UJW
Entry DOI | 10.2210/pdb6ujw/pdb |
Descriptor | ATP-dependent translocase ABCB1, 2,4-dibromophenyl 2,4,6-tribromophenyl ether (2 entities in total) |
Functional Keywords | p-glycoprotein, mdr1, p-gp, pgp, multidrug resistance protein, translocase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 1 |
Total formula weight | 142682.90 |
Authors | Aller, S.G.,Le, C.A. (deposition date: 2019-10-03, release date: 2020-05-27, Last modification date: 2023-10-11) |
Primary citation | Le, C.A.,Harvey, D.S.,Aller, S.G. Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj, 7:663-672, 2020 Cited by PubMed: 32695413DOI: 10.1107/S2052252520005709 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.15 Å) |
Structure validation
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