6DJV
 
 | | Mtb ClpB in complex with ATPgammaS and casein, Conformer 2 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | | 著者 | Yu, H.J, Li, H.L. | | 登録日 | 2018-05-26 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6E10
 | | PTEX Core Complex in the Engaged (Extended) State | | 分子名称: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | | 著者 | Ho, C, Lai, M, Zhou, Z.H. | | 登録日 | 2018-07-08 | | 公開日 | 2018-08-22 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (4.16 Å) | | 主引用文献 | Malaria parasite translocon structure and mechanism of effector export.
Nature, 561, 2018
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6E11
 | | PTEX Core Complex in the Resetting (Compact) State | | 分子名称: | Endogenous cargo polypeptide, Exported protein 2, Heat shock protein 101, ... | | 著者 | Ho, C, Lai, M, Zhou, Z.H. | | 登録日 | 2018-07-08 | | 公開日 | 2018-08-22 | | 最終更新日 | 2019-11-27 | | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | | 主引用文献 | Malaria parasite translocon structure and mechanism of effector export.
Nature, 561, 2018
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6ED3
 | | Mtb ClpB in complex with AMPPNP | | 分子名称: | Chaperone protein ClpB | | 著者 | Yu, H.J, Li, H.L. | | 登録日 | 2018-08-08 | | 公開日 | 2018-09-26 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | | 主引用文献 | ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6EF0
 | | Yeast 26S proteasome bound to ubiquitinated substrate (1D* motor state) | | 分子名称: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | | 著者 | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | | 登録日 | 2018-08-15 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.43 Å) | | 主引用文献 | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
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6EF1
 | | Yeast 26S proteasome bound to ubiquitinated substrate (5D motor state) | | 分子名称: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | | 著者 | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | | 登録日 | 2018-08-15 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.73 Å) | | 主引用文献 | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
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6EF2
 | | Yeast 26S proteasome bound to ubiquitinated substrate (5T motor state) | | 分子名称: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | | 著者 | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | | 登録日 | 2018-08-15 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | | 主引用文献 | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
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6EF3
 | | Yeast 26S proteasome bound to ubiquitinated substrate (4D motor state) | | 分子名称: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | | 著者 | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | | 登録日 | 2018-08-15 | | 公開日 | 2018-10-17 | | 最終更新日 | 2020-01-08 | | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | | 主引用文献 | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation.
Science, 362, 2018
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6EM8
 | | S.aureus ClpC resting state, C2 symmetrised | | 分子名称: | ATP-dependent Clp protease ATP-binding subunit ClpC | | 著者 | Carroni, M, Mogk, A. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
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6EM9
 | | S.aureus ClpC resting state, asymmetric map | | 分子名称: | ATP-dependent Clp protease ATP-binding subunit ClpC | | 著者 | Carroni, M, Mogk, A, Bukau, B, Franke, K. | | 登録日 | 2017-10-01 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
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6EMW
 | | Structure of S.aureus ClpC in complex with MecA | | 分子名称: | ATP-dependent Clp protease ATP-binding subunit, ATP-dependent Clp protease ATP-binding subunit ClpC, Adapter protein MecA, ... | | 著者 | Carroni, M, Mogk, A, Bukau, B, Franke, K. | | 登録日 | 2017-10-03 | | 公開日 | 2017-12-27 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (11 Å) | | 主引用文献 | Regulatory coiled-coil domains promote head-to-head assemblies of AAA+ chaperones essential for tunable activity control.
Elife, 6, 2017
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6EPC
 | | Ground state 26S proteasome (GS2) | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | | 登録日 | 2017-10-11 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (12.3 Å) | | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
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6EPD
 | | Substrate processing state 26S proteasome (SPS1) | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | | 登録日 | 2017-10-11 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (15.4 Å) | | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
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6EPE
 | | Substrate processing state 26S proteasome (SPS2) | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | | 登録日 | 2017-10-11 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (12.8 Å) | | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
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6EPF
 | | Ground state 26S proteasome (GS1) | | 分子名称: | 26S proteasome non-ATPase regulatory subunit 1, 26S proteasome non-ATPase regulatory subunit 11, 26S proteasome non-ATPase regulatory subunit 13, ... | | 著者 | Guo, Q, Lehmer, C, Martinez-Sanchez, A, Rudack, T, Beck, F, Hartmann, H, Hipp, M.S, Hartl, F.U, Edbauer, D, Baumeister, W, Fernandez-Busnadiego, R. | | 登録日 | 2017-10-11 | | 公開日 | 2018-02-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (11.8 Å) | | 主引用文献 | In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
Cell, 172, 2018
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6F0X
 | | Cryo-EM structure of TRIP13 in complex with ATP gamma S, p31comet, C-Mad2 and Cdc20 | | 分子名称: | Cell division cycle protein 20 homolog, MAD2L1-binding protein, Mitotic spindle assembly checkpoint protein MAD2A, ... | | 著者 | Alfieri, C, Chang, L, Barford, D. | | 登録日 | 2017-11-20 | | 公開日 | 2018-05-02 | | 最終更新日 | 2020-12-02 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13.
Nature, 559, 2018
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6FVT
 | | 26S proteasome, s1 state | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | 著者 | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | | 登録日 | 2018-03-05 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep, 24, 2018
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6FVU
 | | 26S proteasome, s2 state | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | 著者 | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | | 登録日 | 2018-03-05 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep, 24, 2018
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6FVV
 | | 26S proteasome, s3 state | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | 著者 | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | | 登録日 | 2018-03-05 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | | 主引用文献 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep, 24, 2018
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6FVW
 | | 26S proteasome, s4 state | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | 著者 | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | | 登録日 | 2018-03-05 | | 公開日 | 2018-08-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep, 24, 2018
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6FVX
 | | 26S proteasome, s5 state | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | 著者 | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | | 登録日 | 2018-03-05 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | | 主引用文献 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep, 24, 2018
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6FVY
 | | 26S proteasome, s6 state | | 分子名称: | 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ... | | 著者 | Eisele, M.R, Reed, R.G, Rudack, T, Schweitzer, A, Beck, F, Nagy, I, Pfeifer, G, Plitzko, J.M, Baumeister, W, Tomko, R.J, Sakata, E. | | 登録日 | 2018-03-05 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | | 主引用文献 | Expanded Coverage of the 26S Proteasome Conformational Landscape Reveals Mechanisms of Peptidase Gating.
Cell Rep, 24, 2018
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6G2V
 | | Crystal structure of the p97 D2 domain in a helical split-washer conformation | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | | 著者 | Stach, L, Morgan, R.M.L, Freemont, P.S. | | 登録日 | 2018-03-23 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.903 Å) | | 主引用文献 | Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding.
Febs Lett., 594, 2020
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6G2W
 | | Crystal structure of the p97 D2 domain in a helical split-washer conformation | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | | 著者 | Stach, L, Morgan, R.M.L, Freemont, P.S. | | 登録日 | 2018-03-23 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.678 Å) | | 主引用文献 | Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding.
Febs Lett., 594, 2020
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6G2X
 | | Crystal structure of the p97 D2 domain in a helical split-washer conformation | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE-5'-DIPHOSPHATE, DIMETHYL SULFOXIDE, ... | | 著者 | Stach, L, Morgan, R.M.L, Freemont, P.S. | | 登録日 | 2018-03-23 | | 公開日 | 2019-04-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.078 Å) | | 主引用文献 | Crystal structure of the catalytic D2 domain of the AAA+ ATPase p97 reveals a putative helical split-washer-type mechanism for substrate unfolding.
Febs Lett., 594, 2020
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