6F0X
Cryo-EM structure of TRIP13 in complex with ATP gamma S, p31comet, C-Mad2 and Cdc20
Summary for 6F0X
Entry DOI | 10.2210/pdb6f0x/pdb |
EMDB information | 4166 |
Descriptor | Pachytene checkpoint protein 2 homolog, MAD2L1-binding protein, Cell division cycle protein 20 homolog, ... (5 entities in total) |
Functional Keywords | aaa+ atpase, remodeller, spindle assembly checkpoint (sac), mitosis, chromosome segregation, cell cycle |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 403673.26 |
Authors | Alfieri, C.,Chang, L.,Barford, D. (deposition date: 2017-11-20, release date: 2018-05-02, Last modification date: 2020-12-02) |
Primary citation | Alfieri, C.,Chang, L.,Barford, D. Mechanism for remodelling of the cell cycle checkpoint protein MAD2 by the ATPase TRIP13. Nature, 559:274-278, 2018 Cited by PubMed: 29973720DOI: 10.1038/s41586-018-0281-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.6 Å) |
Structure validation
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