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5MQH
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BU of 5mqh by Molmil
Structure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilis in a crystal form without domain swapping
分子名称: Serine phosphatase
著者Levdikov, V.M, Wilkinson, A.J, Blagova, E.V.
登録日2016-12-20
公開日2017-05-31
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases.
Elife, 6, 2017
2FOT
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BU of 2fot by Molmil
Crystal structure of the complex between calmodulin and alphaII-spectrin
分子名称: CALCIUM ION, Calmodulin, alpha-II spectrin Spectrin
著者Simonovic, M, Zhang, Z, Cianci, C.D, Steitz, T.A, Morrow, J.S.
登録日2006-01-13
公開日2006-09-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of the calmodulin alphaII-spectrin complex provides insight into the regulation of cell plasticity.
J.Biol.Chem., 281, 2006
4EWA
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BU of 4ewa by Molmil
Study on structure and function relationships in human Pirin with Fe ion
分子名称: FE (III) ION, Pirin
著者Liu, F, Rehmani, I, Chen, L, Fu, R, Serrano, V, Wilson, D.W, Liu, A.
登録日2012-04-26
公開日2013-05-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110, 2013
4BYY
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BU of 4byy by Molmil
Apo GlxR
分子名称: GLYCEROL, PHOSPHATE ION, TRANSCRIPTIONAL REGULATOR, ...
著者Pohl, E, Cann, M.J, Townsend, P.D, Money, V.A.
登録日2013-07-21
公開日2014-07-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献The Crystal Structures of Apo and Camp-Bound Glxr from Corynebacterium Glutamicum Reveal Structural and Dynamic Changes Upon Camp Binding in Crp/Fnr Family Transcription Factors.
Plos One, 9, 2014
7DVV
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BU of 7dvv by Molmil
Heme sensor protein PefR from Streptococcus agalactiae bound to operator DNA (28-mer)
分子名称: DNA (28-MER), HTH marR-type domain-containing protein
著者Nishinaga, M, Nagai, S, Nishitani, Y, Sugimoto, H, Shiro, Y, Sawai, H.
登録日2021-01-15
公開日2021-09-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Heme controls the structural rearrangement of its sensor protein mediating the hemolytic bacterial survival.
Commun Biol, 4, 2021
8AAF
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BU of 8aaf by Molmil
Yeast RQC complex in state G
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-01
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
4CQN
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BU of 4cqn by Molmil
Crystal structure of the E.coli LeuRS-tRNA complex with the non- cognate isoleucyl adenylate analogue
分子名称: ESCHERICHIA COLI TRNA-LEU UAA ISOACCEPTOR, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ...
著者Palencia, A, Cusack, S, Cvetesic, N, Haslaz, I, Gruic-Sovulj, I.
登録日2014-02-20
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Physiological Target for Leurs Translational Quality Control is Norvaline
Embo J., 33, 2014
4E2J
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BU of 4e2j by Molmil
X-Ray Crystal Structure of the Ancestral Glucocorticoid Receptor 2 ligand binding domain in complex with mometasone furoate and TIF-2 coactivator fragment
分子名称: Ancestral Glucocorticoid Receptor 2, FORMIC ACID, GLYCEROL, ...
著者Kohn, J.A, Deshpande, K, Ortlund, E.A.
登録日2012-03-08
公開日2012-03-28
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Deciphering Modern Glucocorticoid Cross-pharmacology Using Ancestral Corticosteroid Receptors.
J.Biol.Chem., 287, 2012
4PFN
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BU of 4pfn by Molmil
Crystal structure of Plasmodium vivax SHMT with L-serine Schiff base
分子名称: CHLORIDE ION, PYRIDOXAL-5'-PHOSPHATE, SERINE, ...
著者Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U.
登録日2014-04-30
公開日2014-12-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of Plasmodium vivax serine hydroxymethyltransferase: implications for ligand-binding specificity and functional control.
Acta Crystallogr.,Sect.D, 70, 2014
6EXQ
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BU of 6exq by Molmil
Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor
分子名称: (3~{S})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-8-methoxy-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide, 1,2-ETHANEDIOL, Cysteine protease
著者Dietzel, U, Kisker, C.
登録日2017-11-08
公開日2018-04-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Repurposing a Library of Human Cathepsin L Ligands: Identification of Macrocyclic Lactams as Potent Rhodesain and Trypanosoma brucei Inhibitors.
J. Med. Chem., 61, 2018
4Q20
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BU of 4q20 by Molmil
Crystal structure of a C-terminal part of tyrosine kinase (DivL) from Caulobacter crescentus CB15 at 2.50 A resolution (PSI Community Target, Shapiro)
分子名称: Sensor protein DivL
著者Joint Center for Structural Genomics (JCSG)
登録日2014-04-04
公開日2014-04-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cell fate regulation governed by a repurposed bacterial histidine kinase.
Plos Biol., 12, 2014
4F9B
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BU of 4f9b by Molmil
Human CDC7 kinase in complex with DBF4 and PHA767491
分子名称: 2-(pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one, Cell division cycle 7-related protein kinase, Protein DBF4 homolog A, ...
著者Hughes, S, Cherepanov, P.
登録日2012-05-18
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human CDC7 kinase in complex with its activator DBF4.
Nat.Struct.Mol.Biol., 19, 2012
6O6H
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BU of 6o6h by Molmil
RIAM cc-RA-PH structure in the P21212 space group
分子名称: Amyloid beta A4 precursor protein-binding family B member 1-interacting protein
著者Wu, J.
登録日2019-03-06
公開日2020-09-02
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Phosphorylation of RIAM by Src Promotes Integrin Activation by Unmasking the PH Domain of RIAM.
Structure, 2020
4G3G
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BU of 4g3g by Molmil
Crystal structure of murine NF-kappaB inducing kinase (NIK) V408L bound to a 2-(aminothiazolyl)phenol (cmp3)
分子名称: 4-fluoro-2-{[4-(pyridin-4-yl)-1,3-thiazol-2-yl]amino}phenol, NF-kappa-beta-inducing kinase
著者Hymowitz, S.
登録日2012-07-13
公開日2012-08-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
Structure, 20, 2012
4G3E
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BU of 4g3e by Molmil
Crystal structure of murine NF-kappaB inducing kinase (NIK) bound to a 6-alkynylindoline (cmp1)
分子名称: (2R)-4-[1-(2-amino-5-chloropyrimidin-4-yl)-2,3-dihydro-1H-indol-6-yl]-2-(1,3-thiazol-2-yl)but-3-yn-2-ol, NF-kappa-beta-inducing kinase, SULFATE ION
著者Hymowitz, S.G, de Leon-Boenig, G.
登録日2012-07-13
公開日2012-08-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
Structure, 20, 2012
4AWA
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BU of 4awa by Molmil
Crystal structure of active legumain in complex with YVAD-CMK at pH 5.0
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, LEGUMAIN, SULFATE ION, ...
著者Dall, E, Brandstetter, H.
登録日2012-06-01
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation
Proc.Natl.Acad.Sci.USA, 110, 2013
6U0S
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BU of 6u0s by Molmil
Crystal structure of the flavin-dependent monooxygenase PieE in complex with FAD and substrate
分子名称: 2,4-dichlorophenol 6-monooxygenase, 2-[(2E,5E,7E,9R,10R,11E)-10-hydroxy-3,7,9,11-tetramethyltrideca-2,5,7,11-tetraen-1-yl]-6-methoxy-3-methylpyridin-4-ol, CHLORIDE ION, ...
著者Shi, R, Manenda, M.
登録日2019-08-14
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Structural analyses of the Group A flavin-dependent monooxygenase PieE reveal a sliding FAD cofactor conformation bridging OUT and IN conformations.
J.Biol.Chem., 295, 2020
4I1Q
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BU of 4i1q by Molmil
Crystal Structure of hBRAP1 N-BAR domain
分子名称: Bridging integrator 2
著者Sanchez-Barrena, M.J.
登録日2012-11-21
公開日2013-02-06
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Bin2 Is a Membrane Sculpting N-BAR Protein That Influences Leucocyte Podosomes, Motility and Phagocytosis
Plos One, 7, 2012
4ME4
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BU of 4me4 by Molmil
Crystal structure of a HD-GYP domain (a cyclic-di-GMP phosphodiesterase) containing a tri-nuclear metal centre
分子名称: FE (III) ION, GUANOSINE-5'-MONOPHOSPHATE, IMIDAZOLE, ...
著者Bellini, D, Walsh, M.A, Oxford Protein Production Facility (OPPF)
登録日2013-08-24
公開日2014-02-19
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre.
Mol.Microbiol., 91, 2014
4GRA
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BU of 4gra by Molmil
Crystal structure of SULT1A1 bound with PAP
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase 1A1
著者Kim, J, Cook, I, Wang, T, Falany, C.N, Leyh, T.S, Almo, S.C.
登録日2012-08-24
公開日2013-01-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献The gate that governs sulfotransferase selectivity.
Biochemistry, 52, 2013
4WU9
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BU of 4wu9 by Molmil
Structure of cisPtNAP-NCP145
分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B 1.1, ...
著者Chua, E.Y.D, Davey, G.E, Chin, C.F, Droge, P, Ang, W.H, Davey, C.A.
登録日2014-10-31
公開日2015-09-02
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Stereochemical control of nucleosome targeting by platinum-intercalator antitumor agents.
Nucleic Acids Res., 43, 2015
8AGV
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BU of 8agv by Molmil
Yeast RQC complex in state H
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGZ
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BU of 8agz by Molmil
Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGW
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BU of 8agw by Molmil
Yeast RQC complex in state D
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023
8AGT
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BU of 8agt by Molmil
Yeast RQC complex in state F
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Tesina, P, Buschauer, R, Beckmann, R.
登録日2022-07-20
公開日2023-03-08
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control.
Mol.Cell, 83, 2023

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