Study on structure and function relationships in human Pirin with Fe ion

Summary for 4EWA

Related4ERO 4EWB 4EWD 4EWE
DescriptorPirin, FE (III) ION (3 entities in total)
Functional Keywordsbeta sandwich, cupin, iron, metal binding protein, transcription cofactor activity, protein binding, nucleus, oxidoreductase
Biological sourceHomo sapiens (human)
Cellular locationNucleus O00625
Total number of polymer chains1
Total molecular weight32215.24
Liu, F.,Rehmani, I.,Chen, L.,Fu, R.,Serrano, V.,Wilson, D.W.,Liu, A. (deposition date: 2012-04-26, release date: 2013-05-29, Last modification date: 2013-09-04)
Primary citation
Liu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,de Serrano, V.,Liu, A.
Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110:9722-9727, 2013
PubMed: 23716661 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1221743110
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.29360.3%4.1%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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