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4EWE

Study on structure and function relationships in human Pirin with Manganese ion

Summary for 4EWE
Entry DOI10.2210/pdb4ewe/pdb
Related4ERO 4EWA 4EWB 4EWD
DescriptorPirin, MANGANESE (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsbeta sandwich, cupin, metal binding protein, transcription cofactor activity, protein binding, nucleus, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationNucleus : O00625
Total number of polymer chains1
Total formula weight32462.60
Authors
Liu, F.,Rehmani, I.,Fu, R.,Esaka, S.,Chen, L.,Serrano, V.,Liu, A. (deposition date: 2012-04-26, release date: 2013-05-29, Last modification date: 2024-02-28)
Primary citationLiu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,de Serrano, V.,Liu, A.
Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110:9722-9727, 2013
Cited by
PubMed: 23716661
DOI: 10.1073/pnas.1221743110
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.56 Å)
Structure validation

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