4ERO

Study on structure and function relationships in human Pirin with Cobalt ion

Summary for 4ERO

Entry DOI	10.2210/pdb4ero/pdb
Related	4EWA 4EWB 4EWD 4EWE
Descriptor	Pirin, COBALT (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	beta sandwich, cupin, metatl binding protein, transcription activity, protein binding, nucleus, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: O00625
Total number of polymer chains	1
Total formula weight	32466.60
Authors	Liu, F.,Rehmani, I.,Fu, R.,Esaka, S.,Chen, L.,Serrano, V.,Liu, A. (deposition date: 2012-04-20, release date: 2013-05-29, Last modification date: 2024-02-28)
Primary citation	Liu, F.,Rehmani, I.,Esaki, S.,Fu, R.,Chen, L.,de Serrano, V.,Liu, A. Pirin is an iron-dependent redox regulator of NF-kappa B. Proc.Natl.Acad.Sci.USA, 110:9722-9727, 2013 Cited by PubMed: 23716661 DOI: 10.1073/pnas.1221743110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation