4EWA

Study on structure and function relationships in human Pirin with Fe ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003712	molecular_function	transcription coregulator activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006366	biological_process	transcription by RNA polymerase II
A	0007586	biological_process	digestion
A	0008127	molecular_function	quercetin 2,3-dioxygenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016604	cellular_component	nuclear body
A	0030099	biological_process	myeloid cell differentiation
A	0030224	biological_process	monocyte differentiation
A	0046872	molecular_function	metal ion binding
A	0051213	molecular_function	dioxygenase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 1001

Chain	Residue
A	HIS56
A	HIS58
A	HIS101
A	GLU103
A	HOH1128

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:14573596, ECO:0000269|PubMed:20711196, ECO:0007744|PDB:1J1L, ECO:0007744|PDB:3ACL

Chain	Residue	Details
A	GLU103
A	HIS56
A	HIS58
A	HIS101

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