PDB: 250 件ウェブページステータス検索Chemie searchBIRD

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7ZEW	Complex Cyp33-RRM : AAUAAA RNA 分子名称: Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*AP*AP*UP*AP*AP*A)-3') 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2023-05-03 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEV	Free form of extended Cyp33-RRM 分子名称: Peptidyl-prolyl cis-trans isomerase E 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2023-05-03 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEX	Complex Cyp33-RRMdelta alpha : UAAUGUCG RNA 分子名称: Isoform 3 of Peptidyl-prolyl cis-trans isomerase E, RNA (5'-R(*UP*AP*AP*UP*GP*UP*CP*G)-3') 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-05-04 最終更新日 2023-05-03 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
7ZEY	Complex Cyp33-RRM : MLL1-PHD3 分子名称: MLL cleavage product N320, Peptidyl-prolyl cis-trans isomerase E, ZINC ION 著者 Blatter, M, Allain, F, Meylan, C. 登録日 2022-03-31 公開日 2022-04-13 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Sci Adv, 9, 2023
6L87	Solution structure of the tandem PWWP-ARID domains of human RBBP1 分子名称: AT-rich interactive domain-containing protein 4A 著者 Gong, W.B, Perrett, S, Feng, Y.G. 登録日 2019-11-05 公開日 2021-01-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Structural insight into chromatin recognition by multiple domains of the tumor suppressor RBBP1. J.Mol.Biol., 2021
7EA1	Crystal Structure of Spindlin1 bound to SPINDOC Docpep2 分子名称: Peptide from Spindlin interactor and repressor of chromatin-binding protein, Spindlin-1 著者 Zhao, F, Li, H. 登録日 2021-03-05 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular basis for SPINDOC-Spindlin1 engagement and its role in transcriptional inhibition to be published
7E9M	Crystal Structure of Spindlin1 bound to SPINDOC Docpep3 分子名称: Peptide from Spindlin interactor and repressor of chromatin-binding protein, Spindlin-1 著者 Zhao, F, Li, H. 登録日 2021-03-04 公開日 2022-06-15 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular basis for SPINDOC-Spindlin1 engagement and its role in transcriptional inhibition to be published
2M1R	PHD domain of ING4 N214D mutant 分子名称: Inhibitor of growth protein 4, ZINC ION 著者 Blanco, F.J. 登録日 2012-12-05 公開日 2012-12-26 実験手法 SOLUTION NMR 主引用文献 Functional impact of cancer-associated mutations in the tumor suppressor protein ING4. Carcinogenesis, 31, 2010
2MUM	Solution structure of the PHD domain of Yeast YNG2 分子名称: Chromatin modification-related protein YNG2, ZINC ION 著者 Taeb, S, Kaustov, L, Lemak, A, Farhadi, S, Sheng, Y. 登録日 2014-09-12 公開日 2014-12-24 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution structure of the PHD domain of Yeast YNG2 To be Published
2NS2	Crystal Structure of Spindlin1 分子名称: PHOSPHATE ION, Spindlin-1 著者 Zhao, Q, Qin, L, Jiang, F, Wu, B, Yue, W, Xu, F, Rong, Z, Yuan, H, Xie, X, Gao, Y, Bai, C, Bartlam, M. 登録日 2006-11-02 公開日 2006-11-28 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of human spindlin1. Tandem tudor-like domains for cell cycle regulation J.Biol.Chem., 282, 2007
2PUY	Crystal Structure of the BHC80 PHD finger 分子名称: Histone H3, PHD finger protein 21A, ZINC ION 著者 Horton, J.R, Cheng, X, Collins, R.E. 登録日 2007-05-09 公開日 2007-08-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression. Nature, 448, 2007
2RSD	Solution structure of the plant homeodomain (PHD) of the E3 SUMO ligase Siz1 from rice 分子名称: E3 SUMO-protein ligase SIZ1, ZINC ION 著者 Shindo, H, Tsuchiya, W, Suzuki, R, Yamazaki, T. 登録日 2012-01-12 公開日 2012-08-15 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2 Febs Lett., 586, 2012
4LLB	Crystal Structure of MOZ double PHD finger histone H3K14ac complex 分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-09 公開日 2013-10-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4LKA	Crystal Structure of MOZ double PHD finger histone H3K9ac complex 分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-07 公開日 2013-10-16 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4LJN	Crystal Structure of MOZ double PHD finger 分子名称: Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-05 公開日 2013-10-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4LK9	Crystal Structure of MOZ double PHD finger histone H3 tail complex 分子名称: Histone H3.1, Histone acetyltransferase KAT6A, ZINC ION 著者 Dreveny, I, Deeves, S.E, Yue, B, Heery, D.M. 登録日 2013-07-07 公開日 2013-10-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The double PHD finger domain of MOZ/MYST3 induces alpha-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification. Nucleic Acids Res., 42, 2014
4FWJ	Native structure of LSD2/AOF1/KDM1b in spacegroup of I222 at 2.9A 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, PHOSPHATE ION, ... 著者 Zhang, Q, Chen, Z. 登録日 2012-07-01 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4FWE	Native structure of LSD2 /AOF1/KDM1b in spacegroup of C2221 at 2.13A 分子名称: CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... 著者 Zhang, Q, Chen, Z. 登録日 2012-07-01 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4FWF	Complex structure of LSD2/AOF1/KDM1b with H3K4 mimic 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.1, Lysine-specific histone demethylase 1B, ... 著者 Zhang, Q, Chen, Z. 登録日 2012-07-01 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Cell Res., 23, 2013
4GU0	Crystal structure of LSD2 with H3 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3, Lysine-specific histone demethylase 1B, ... 著者 Chen, F, Yang, H, Dong, Z, Fang, J, Zhu, T, Gong, W, Xu, Y. 登録日 2012-08-29 公開日 2013-02-13 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.103 Å) 主引用文献 Structural insight into substrate recognition by histone demethylase LSD2/KDM1b Cell Res., 23, 2013
4GUS	Crystal structure of LSD2-NPAC with H3 in space group P3221 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
5VAR	Crystal structure of KDM4A tandem TUDOR domain in complex with a tri-methyl lysine competitive inhibitor 分子名称: (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol, Lysine-specific demethylase 4A 著者 Judge, R.A, Upadhyay, A.K. 登録日 2017-03-27 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach. Bioorg. Med. Chem. Lett., 28, 2018
4GUR	Crystal structure of LSD2-NPAC with H3 in space group P21 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.506 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
4GUT	Crystal structure of LSD2-NPAC 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Lysine-specific histone demethylase 1B, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.998 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
4GU1	Crystal structure of LSD2 分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1B, ... 著者 Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. 登録日 2012-08-29 公開日 2013-01-16 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.939 Å) 主引用文献 LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013

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