8TED
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8TB5
| TYK2 JH2 bound to Compound7 | 分子名称: | ACETATE ION, N-{(3P)-3-[3-(dimethylsulfamoyl)phenyl]-1H-pyrrolo[2,3-c]pyridin-5-yl}cyclopropanecarboxamide, Non-receptor tyrosine-protein kinase TYK2 | 著者 | Argiriadi, M.A, Van Epps, S.A, Breinlinger, E.C. | 登録日 | 2023-06-28 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712. J.Med.Chem., 66, 2023
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8T9H
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8T9F
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8T8D
| Structure of Helicobacter pylori adhesin A, HpaA | 分子名称: | ACETATE ION, GLYCEROL, Neuraminyllactose-binding hemagglutinin | 著者 | Martini, C, Calmettes, C. | 登録日 | 2023-06-22 | 公開日 | 2024-01-31 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Unraveling the crystal structure of the HpaA adhesin: insights into cell adhesion function and epitope localization of a Helicobacter pylori vaccine candidate. Mbio, 15, 2024
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8T5I
| Crystal structure of human WDR5 in complex with MR4397 | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, N-[(2S)-1-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1-oxopentan-2-yl]-3-[(1H-imidazol-1-yl)methyl]benzamide, ... | 著者 | Kimani, S, Dong, A, Li, F, Loppnau, P, Ackloo, S, Vedadi, M, Brown, P.J, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-13 | 公開日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of human WDR5 in complex with MR4397 To be published
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8T4R
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8T3Y
| Structure of Bre1-nucleosome complex - state1 | 分子名称: | 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ... | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | 登録日 | 2023-06-08 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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8T3W
| Structure of Bre1-nucleosome complex - state2 | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | 登録日 | 2023-06-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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8T3T
| Structure of Bre1-nucleosome complex - state3 | 分子名称: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | 著者 | Zhao, F, Hicks, C.W, Wolberger, C. | 登録日 | 2023-06-07 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-22 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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8T0P
| Structure of Cse4 bound to Ame1 and Okp1 | 分子名称: | Histone H3-like centromeric protein CSE4, Inner kinetochore subunit AME1, Inner kinetochore subunit OKP1, ... | 著者 | Deng, S, Harrison, S.C. | 登録日 | 2023-06-01 | 公開日 | 2023-09-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Recognition of centromere-specific histone Cse4 by the inner kinetochore Okp1-Ame1 complex. Embo Rep., 24, 2023
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8SYP
| Genomic CX3CR1 nucleosome | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Lian, T, Guan, R, Bai, Y. | 登録日 | 2023-05-25 | 公開日 | 2023-11-01 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha. Nat.Struct.Mol.Biol., 31, 2024
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8SWP
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8SWI
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8SW2
| Porous framework formed by assembly of a bipyridyl-conjugated helical peptide | 分子名称: | 5'-(hydrazinecarbonyl)[2,2'-bipyridine]-5-carboxamide, ACETATE ION, LEU-AIB-ALA-SER-LEU-ALA-CYS-AIB-LEU, ... | 著者 | Hess, S.S, Nguyen, A.I. | 登録日 | 2023-05-17 | 公開日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Noncovalent Peptide Assembly Enables Crystalline, Permutable, and Reactive Thiol Frameworks. J.Am.Chem.Soc., 145, 2023
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8SVF
| BAP1/ASXL1 bound to the H2AK119Ub Nucleosome | 分子名称: | DNA/RNA (187-MER), DNA/RNA (327-MER), Histone H2A type 1, ... | 著者 | Thomas, J.F, Valencia-Sanchez, M.I, Armache, K.-J. | 登録日 | 2023-05-16 | 公開日 | 2023-08-30 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of histone H2A lysine 119 deubiquitination by Polycomb repressive deubiquitinase BAP1/ASXL1. Sci Adv, 9, 2023
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8SV4
| 7-Deazapurines and 5-Halogenpyrimidine DNA duplex | 分子名称: | 1,2-ETHANEDIOL, 2-[2-(2-ethoxyethoxy)ethoxy]ethanol, ACETATE ION, ... | 著者 | Pallan, P.S, Egli, M. | 登録日 | 2023-05-15 | 公開日 | 2023-10-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry, 62, 2023
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8SSO
| AurA bound to danusertib and inhibiting monobody Mb2 | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Aurora kinase A, ... | 著者 | Ludewig, H, Kim, C, Kern, D. | 登録日 | 2023-05-08 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | A biophysical framework for double-drugging kinases. Proc.Natl.Acad.Sci.USA, 120, 2023
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8SSK
| Citrobacter rodentium contact dependent growth inhibition (CDI) entry and toxin (CdiA-CT) domains | 分子名称: | ACETATE ION, CALCIUM ION, Contact-dependent inhibitor A, ... | 著者 | Cuthbert, B.J, Goulding, C.W, Hayes, C.S, Nhan, D.Q. | 登録日 | 2023-05-08 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Citrobacter rodentium contact dependent growth inhibition (CDI) entry and toxin (CdiA-CT) domains To Be Published
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8SR6
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8SQW
| particulate methane monooxygenase crosslinked with 2,2,2-trifluoroethanol bound | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-dihexanoyl-sn-glycero-3-phosphocholine, Ammonia monooxygenase/methane monooxygenase, ... | 著者 | Tucci, F.J, Rosenzweig, A.C. | 登録日 | 2023-05-04 | 公開日 | 2023-11-15 | 最終更新日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (2.16 Å) | 主引用文献 | Product analog binding identifies the copper active site of particulate methane monooxygenase. Nat Catal, 6, 2023
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8SQR
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8SQP
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8SPU
| Structure of ESRRB nucleosome bound OCT4 at site c | 分子名称: | DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Lian, T, Guan, R, Bai, Y. | 登録日 | 2023-05-03 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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8SPS
| High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b | 分子名称: | DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | 著者 | Lian, T, Guan, R, Bai, Y. | 登録日 | 2023-05-03 | 公開日 | 2023-06-28 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
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