8SV4

7-Deazapurines and 5-Halogenpyrimidine DNA duplex

Summary for 8SV4

Entry DOI	10.2210/pdb8sv4/pdb
Descriptor	Ribonuclease H, DNA (5'-D((B86)P(7DD)P(B86)P(7DD)P(7DA)P(7DA)P(UCL)P(UCL)P(B86)P(7DD)P(B86)P(7DD))-3'), 2-[2-(2-ethoxyethoxy)ethoxy]ethanol, ... (7 entities in total)
Functional Keywords	7-deazapurines, 5-halogenpyrimidines, adenine-tract geometry, rnase-h complex, dna duplex, dickerson-drew dodecamer, dna duplex crystal structure, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
Biological source	Halalkalibacterium halodurans More
Total number of polymer chains	3
Total formula weight	24260.56
Authors	Pallan, P.S.,Egli, M. (deposition date: 2023-05-15, release date: 2023-10-04, Last modification date: 2023-10-11)
Primary citation	Pallan, P.S.,Lybrand, T.P.,Rozners, E.,Abramov, M.,Schepers, G.,Eremeeva, E.,Herdewijn, P.,Egli, M. Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry, 62:2854-2867, 2023 Cited by PubMed: 37694722 DOI: 10.1021/acs.biochem.3c00327 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation