8T4R

RAG2-PHD finger in complex with H3K4tBuNle peptide

Summary for 8T4R

Entry DOI	10.2210/pdb8t4r/pdb
Descriptor	V(D)J recombination-activating protein 2, H3 histone peptide, ZINC ION, ... (4 entities in total)
Functional Keywords	epigenetics, reader protein, complex, protein binding
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	13713.12
Authors	Kean, K.M.,Travis, C.R.,Waters, M.L. (deposition date: 2023-06-09, release date: 2024-02-14)
Primary citation	Travis, C.R.,Kean, K.M.,Albanese, K.I.,Henriksen, H.C.,Treacy, J.W.,Chao, E.Y.,Houk, K.N.,Waters, M.L. Trimethyllysine Reader Proteins Exhibit Widespread Charge-Agnostic Binding via Different Mechanisms to Cationic and Neutral Ligands. J.Am.Chem.Soc., 146:3086-3093, 2024 Cited by PubMed: 38266163 DOI: 10.1021/jacs.3c10031 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.2 Å)

Structure validation