8SSO
AurA bound to danusertib and inhibiting monobody Mb2
Summary for 8SSO
Entry DOI | 10.2210/pdb8sso/pdb |
Descriptor | Aurora kinase A, Mb2, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | complex, kinase, monobody, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 86818.75 |
Authors | |
Primary citation | Kim, C.,Ludewig, H.,Hadzipasic, A.,Kutter, S.,Nguyen, V.,Kern, D. A biophysical framework for double-drugging kinases. Proc.Natl.Acad.Sci.USA, 120:e2304611120-e2304611120, 2023 Cited by PubMed: 37590418DOI: 10.1073/pnas.2304611120 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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