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7VQQ
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BU of 7vqq by Molmil
Cryo-EM structure of amyloid fibril formed by FUS low complexity domain
Descriptor: fusion protein of mCerulean and FUS LCD
Authors:Sun, Y.P, Xia, W.C, Liu, C.
Deposit date:2021-10-20
Release date:2021-12-22
Last modified:2022-02-23
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular structure of an amyloid fibril formed by FUS low-complexity domain.
Iscience, 25, 2022
7CYL
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BU of 7cyl by Molmil
Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Chook, Y.M.
Deposit date:2020-09-03
Release date:2021-02-24
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X).
Sci Rep, 11, 2021
6XFM
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BU of 6xfm by Molmil
Molecular structure of the core of amyloid-like fibrils formed by residues 111-214 of FUS
Descriptor: RNA-binding protein FUS
Authors:Tycko, R, Lee, M, Ghosh, U, Thurber, K, Kato, M.
Deposit date:2020-06-15
Release date:2020-10-07
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS.
Nat Commun, 11, 2020
6SNJ
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BU of 6snj by Molmil
Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III
Descriptor: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER)
Authors:Campagne, S, Allain, F.H.
Deposit date:2019-08-26
Release date:2020-10-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis.
Nat Commun, 11, 2020
6GBM
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BU of 6gbm by Molmil
Solution structure of FUS-RRM bound to stem-loop RNA
Descriptor: RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS
Authors:Loughlin, F.E, Allain, F.H.-T.
Deposit date:2018-04-15
Release date:2019-02-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell, 73, 2019
6G99
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BU of 6g99 by Molmil
Solution structure of FUS-ZnF bound to UGGUG
Descriptor: RNA (5'-R(*UP*GP*GP*UP*G)-3'), RNA-binding protein FUS, ZINC ION
Authors:Loughlin, F.E, Allain, F.H.-T.
Deposit date:2018-04-10
Release date:2019-02-20
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity.
Mol. Cell, 73, 2019
5W3N
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BU of 5w3n by Molmil
Molecular structure of FUS low sequence complexity domain protein fibrils
Descriptor: RNA-binding protein FUS
Authors:Murray, D.T, Kato, M, Lin, Y, Thurber, K, Hung, I, McKnight, S, Tycko, R.
Deposit date:2017-06-08
Release date:2017-09-27
Last modified:2023-06-14
Method:SOLID-STATE NMR
Cite:Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Cell, 171, 2017
5YVG
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BU of 5yvg by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (4.05 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YVH
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BU of 5yvh by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(371-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5YVI
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BU of 5yvi by Molmil
Crystal structure of Karyopherin beta2 in complex with FUS(456-526)
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Yoshizawa, T, Fung, H.Y.J, Chook, Y.M.
Deposit date:2017-11-25
Release date:2018-05-16
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Cell, 173, 2018
5XSG
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BU of 5xsg by Molmil
Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED
Descriptor: RNA-binding protein FUS
Authors:Luo, F, Gui, X, Zhou, H, Li, D, Li, X, Liu, C.
Deposit date:2017-06-14
Release date:2018-04-04
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.73 Å)
Cite:Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
5XRR
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BU of 5xrr by Molmil
Crystal structure of FUS (54-59) SYSSYG
Descriptor: RNA-binding protein FUS, ZINC ION
Authors:Zhao, M, Gui, X, Li, D, Liu, C.
Deposit date:2017-06-09
Release date:2018-04-04
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation.
Nat. Struct. Mol. Biol., 25, 2018
4FDD
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BU of 4fdd by Molmil
Crystal structure of KAP beta2-PY-NLS
Descriptor: RNA-binding protein FUS, Transportin-1
Authors:Zhang, Z.C, Chook, Y.M.
Deposit date:2012-05-28
Release date:2012-07-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS).
Proc.Natl.Acad.Sci.USA, 109, 2012
2LCW
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BU of 2lcw by Molmil
solution structure of FUS/TLS RRM domain
Descriptor: RNA-binding protein FUS
Authors:Liu, X, Ren, J, Niu, C, Gong, W, Feng, W.
Deposit date:2011-05-10
Release date:2012-06-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:TLS-RRM is a promiscuous nucleic acid binding domain
To be Published
2LA6
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BU of 2la6 by Molmil
Solution NMR Structure of RRM domain of RNA-binding protein FUS from homo sapiens, Northeast Structural Genomics Consortium Target HR6430A
Descriptor: RNA-binding protein FUS
Authors:Liu, G, Xiao, R, Janjua, H, Ciccosanti, C, Wang, H, Lee, H, Acton, T.B, Everett, J.K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2011-03-04
Release date:2011-05-04
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Northeast Structural Genomics Consortium Target HR6430A
To be Published
6KJ3
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BU of 6kj3 by Molmil
120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.6 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ4
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BU of 6kj4 by Molmil
120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.65 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ2
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BU of 6kj2 by Molmil
200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.67 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6KJ1
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BU of 6kj1 by Molmil
200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A
Descriptor: RNA-binding protein FUS
Authors:Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X.
Deposit date:2019-07-20
Release date:2019-10-02
Last modified:2024-03-27
Method:ELECTRON CRYSTALLOGRAPHY (0.65 Å)
Cite:Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules.
Anal.Chem., 91, 2019
6BZP
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BU of 6bzp by Molmil
STGGYG from low-complexity domain of FUS, residues 77-82
Descriptor: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, RNA-binding protein FUS
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S.
Deposit date:2017-12-25
Release date:2018-04-04
Last modified:2024-03-13
Method:ELECTRON CRYSTALLOGRAPHY (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
4IED
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BU of 4ied by Molmil
Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Class D beta-lactamase, ...
Authors:Mangani, S, Benvenuti, M, Docquier, J.D.
Deposit date:2012-12-13
Release date:2014-01-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum
To be Published
4FQ3
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BU of 4fq3 by Molmil
Crystal structure of transportin/FUS-NLS
Descriptor: Fusion (Involved in t(12;16) in malignant liposarcoma), Transportin-1
Authors:Gong, W, Niu, C, Jia, M, Gao, F.
Deposit date:2012-06-25
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of transportin/FUS-NLS
To be Published
6BXV
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BU of 6bxv by Molmil
SYSSYGQS from low-complexity domain of FUS, residues 54-61
Descriptor: FUS
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S.
Deposit date:2017-12-19
Release date:2018-04-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
6BWZ
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BU of 6bwz by Molmil
SYSGYS from low-complexity domain of FUS, residues 37-42
Descriptor: SYSGYS peptide from low-complexity domain of FUS
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Tamir, G, Eisenberg, D.S.
Deposit date:2017-12-15
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
3RKI
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BU of 3rki by Molmil
Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0
Authors:Swanson, K.A, Settembre, E.C, Shaw, C.A, Dey, A.K, Rappuoli, R, Mandl, C.W, Dormitzer, P.D, Carfi, A.
Deposit date:2011-04-18
Release date:2011-05-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers.
Proc.Natl.Acad.Sci.USA, 108, 2011

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