PDB: 136 件ウェブページステータス検索Chemie searchBIRD

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7VQQ	Cryo-EM structure of amyloid fibril formed by FUS low complexity domain 分子名称: fusion protein of mCerulean and FUS LCD 著者 Sun, Y.P, Xia, W.C, Liu, C. 登録日 2021-10-20 公開日 2021-12-22 最終更新日 2022-02-23 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular structure of an amyloid fibril formed by FUS low-complexity domain. Iscience, 25, 2022
7CYL	Crystal structure of Karyopherin-beta2 in complex with FUS PY-NLS(P525L) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Chook, Y.M. 登録日 2020-09-03 公開日 2021-02-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Mechanism of karyopherin-beta 2 binding and nuclear import of ALS variants FUS(P525L) and FUS(R495X). Sci Rep, 11, 2021
6XFM	Molecular structure of the core of amyloid-like fibrils formed by residues 111-214 of FUS 分子名称: RNA-binding protein FUS 著者 Tycko, R, Lee, M, Ghosh, U, Thurber, K, Kato, M. 登録日 2020-06-15 公開日 2020-10-07 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 Molecular structure and interactions within amyloid-like fibrils formed by a low-complexity protein sequence from FUS. Nat Commun, 11, 2020
6SNJ	Solution structure of the FUS/TLS RNA recognition motif in complex with U1 snRNA stem loop III 分子名称: RNA-binding protein FUS, U1 snRNA stem loop III, RNA (28-MER) 著者 Campagne, S, Allain, F.H. 登録日 2019-08-26 公開日 2020-10-28 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis. Nat Commun, 11, 2020
6GBM	Solution structure of FUS-RRM bound to stem-loop RNA 分子名称: RNA (5'-R(*GP*GP*CP*AP*GP*AP*UP*UP*AP*CP*AP*AP*UP*UP*CP*UP*AP*UP*UP*UP*GP*CP*C)-3'), RNA-binding protein FUS 著者 Loughlin, F.E, Allain, F.H.-T. 登録日 2018-04-15 公開日 2019-02-20 最終更新日 2019-05-08 実験手法 SOLUTION NMR 主引用文献 The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. Mol. Cell, 73, 2019
6G99	Solution structure of FUS-ZnF bound to UGGUG 分子名称: RNA (5'-R(*UP*GP*GP*UP*G)-3'), RNA-binding protein FUS, ZINC ION 著者 Loughlin, F.E, Allain, F.H.-T. 登録日 2018-04-10 公開日 2019-02-20 最終更新日 2019-05-08 実験手法 SOLUTION NMR 主引用文献 The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity. Mol. Cell, 73, 2019
5W3N	Molecular structure of FUS low sequence complexity domain protein fibrils 分子名称: RNA-binding protein FUS 著者 Murray, D.T, Kato, M, Lin, Y, Thurber, K, Hung, I, McKnight, S, Tycko, R. 登録日 2017-06-08 公開日 2017-09-27 最終更新日 2023-06-14 実験手法 SOLID-STATE NMR 主引用文献 Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains. Cell, 171, 2017
5YVG	Crystal structure of Karyopherin beta2 in complex with FUS(full length) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5YVH	Crystal structure of Karyopherin beta2 in complex with FUS(371-526) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5YVI	Crystal structure of Karyopherin beta2 in complex with FUS(456-526) 分子名称: RNA-binding protein FUS, Transportin-1 著者 Yoshizawa, T, Fung, H.Y.J, Chook, Y.M. 登録日 2017-11-25 公開日 2018-05-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites. Cell, 173, 2018
5XSG	Ultrahigh resolution structure of FUS (37-42) SYSGYS determined by MicroED 分子名称: RNA-binding protein FUS 著者 Luo, F, Gui, X, Zhou, H, Li, D, Li, X, Liu, C. 登録日 2017-06-14 公開日 2018-04-04 最終更新日 2024-03-27 実験手法 ELECTRON CRYSTALLOGRAPHY (0.73 Å) 主引用文献 Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. Nat. Struct. Mol. Biol., 25, 2018
5XRR	Crystal structure of FUS (54-59) SYSSYG 分子名称: RNA-binding protein FUS, ZINC ION 著者 Zhao, M, Gui, X, Li, D, Liu, C. 登録日 2017-06-09 公開日 2018-04-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.503 Å) 主引用文献 Atomic structures of FUS LC domain segments reveal bases for reversible amyloid fibril formation. Nat. Struct. Mol. Biol., 25, 2018
4FDD	Crystal structure of KAP beta2-PY-NLS 分子名称: RNA-binding protein FUS, Transportin-1 著者 Zhang, Z.C, Chook, Y.M. 登録日 2012-05-28 公開日 2012-07-18 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and energetic basis of ALS-causing mutations in the atypical proline-tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS). Proc.Natl.Acad.Sci.USA, 109, 2012
2LCW	solution structure of FUS/TLS RRM domain 分子名称: RNA-binding protein FUS 著者 Liu, X, Ren, J, Niu, C, Gong, W, Feng, W. 登録日 2011-05-10 公開日 2012-06-06 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 TLS-RRM is a promiscuous nucleic acid binding domain To be Published
2LA6	Solution NMR Structure of RRM domain of RNA-binding protein FUS from homo sapiens, Northeast Structural Genomics Consortium Target HR6430A 分子名称: RNA-binding protein FUS 著者 Liu, G, Xiao, R, Janjua, H, Ciccosanti, C, Wang, H, Lee, H, Acton, T.B, Everett, J.K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2011-03-04 公開日 2011-05-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Northeast Structural Genomics Consortium Target HR6430A To be Published
6KJ3	120kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.60 A 分子名称: RNA-binding protein FUS 著者 Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. 登録日 2019-07-20 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 ELECTRON CRYSTALLOGRAPHY (0.6 Å) 主引用文献 Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Anal.Chem., 91, 2019
6KJ4	120kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.65 A 分子名称: RNA-binding protein FUS 著者 Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. 登録日 2019-07-20 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 ELECTRON CRYSTALLOGRAPHY (0.65 Å) 主引用文献 Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Anal.Chem., 91, 2019
6KJ2	200kV MicroED structure of FUS (37-42) SYSGYS solved from single crystal at 0.67 A 分子名称: RNA-binding protein FUS 著者 Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. 登録日 2019-07-20 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 ELECTRON CRYSTALLOGRAPHY (0.67 Å) 主引用文献 Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Anal.Chem., 91, 2019
6KJ1	200kV MicroED structure of FUS (37-42) SYSGYS solved from merged datasets at 0.65 A 分子名称: RNA-binding protein FUS 著者 Zhou, H, Luo, F, Luo, Z, Li, D, Liu, C, Li, X. 登録日 2019-07-20 公開日 2019-10-02 最終更新日 2024-03-27 実験手法 ELECTRON CRYSTALLOGRAPHY (0.65 Å) 主引用文献 Programming Conventional Electron Microscopes for Solving Ultrahigh-Resolution Structures of Small and Macro-Molecules. Anal.Chem., 91, 2019
6BZP	STGGYG from low-complexity domain of FUS, residues 77-82 分子名称: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, RNA-binding protein FUS 著者 Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. 登録日 2017-12-25 公開日 2018-04-04 最終更新日 2024-03-13 実験手法 ELECTRON CRYSTALLOGRAPHY (1.1 Å) 主引用文献 Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
4IED	Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Class D beta-lactamase, ... 著者 Mangani, S, Benvenuti, M, Docquier, J.D. 登録日 2012-12-13 公開日 2014-01-22 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal Structure of FUS-1 (OXA-85), a Class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum To be Published
4FQ3	Crystal structure of transportin/FUS-NLS 分子名称: Fusion (Involved in t(12;16) in malignant liposarcoma), Transportin-1 著者 Gong, W, Niu, C, Jia, M, Gao, F. 登録日 2012-06-25 公開日 2013-08-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of transportin/FUS-NLS To be Published
6BXV	SYSSYGQS from low-complexity domain of FUS, residues 54-61 分子名称: FUS 著者 Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S. 登録日 2017-12-19 公開日 2018-04-04 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
6BWZ	SYSGYS from low-complexity domain of FUS, residues 37-42 分子名称: SYSGYS peptide from low-complexity domain of FUS 著者 Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Tamir, G, Eisenberg, D.S. 登録日 2017-12-15 公開日 2018-04-04 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks. Science, 359, 2018
3RKI	Structural basis for immunization with post-fusion RSV F to elicit high neutralizing antibody titers 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0 著者 Swanson, K.A, Settembre, E.C, Shaw, C.A, Dey, A.K, Rappuoli, R, Mandl, C.W, Dormitzer, P.D, Carfi, A. 登録日 2011-04-18 公開日 2011-05-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers. Proc.Natl.Acad.Sci.USA, 108, 2011

 

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