PDB: 108 件ウェブページステータス検索Chemie searchBIRD

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6VGG	Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), and mithramycin, in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Rohr, J, Tsodikov, O.V. 登録日 2020-01-08 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.31 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6VGE	Crystal structure of the DNA binding domains of human transcription factor ERG, human Runx2 bound to core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.25 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
4IRH	Auto-inhibited ERG Ets domain 分子名称: Transcriptional regulator ERG 著者 Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H. 登録日 2013-01-14 公開日 2013-07-31 最終更新日 2013-08-28 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc.Natl.Acad.Sci.USA, 110, 2013
4IRI	Auto-inhibited ERG Ets Domain-DNA Complex 分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*G)-3'), Transcriptional regulator ERG 著者 Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H. 登録日 2013-01-14 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc.Natl.Acad.Sci.USA, 110, 2013
4IRG	Uninhibited DNA-binding domain of the Ets transcription factor ERG 分子名称: Transcriptional regulator ERG 著者 Regan, M.C, Horanyi, P.S, Pryor, E.E, Sarver, J.L, Cafiso, D.S, Bushweller, J.H. 登録日 2013-01-14 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proc.Natl.Acad.Sci.USA, 110, 2013
1SXE	The solution structure of the Pointed (PNT) domain from the transcrition factor Erg 分子名称: Transcriptional regulator ERG 著者 Mackereth, C.D, Schaerpf, M, Gentile, L.N, MacIntosh, S.E, Slupsky, C.M, McIntosh, L.P. 登録日 2004-03-30 公開日 2004-09-21 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Diversity in Structure and Function of the Ets Family PNT Domains. J.Mol.Biol., 342, 2004
5YBC	X-ray structure of native ETS-domain domain of Ergp55 分子名称: GLYCEROL, Transcriptional regulator ERG 著者 Saxena, A.K, Gangwar, S.P. 登録日 2017-09-04 公開日 2018-09-19 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence Acta Crystallogr F Struct Biol Commun, 74, 2018
5YBD	X-ray structure of ETS domain of Ergp55 in complex with E74DNA 分子名称: DNA (5'-D(P*AP*CP*CP*GP*GP*AP*AP*GP*T)-3'), DNA (5'-D(P*CP*AP*CP*TP*TP*CP*CP*GP*GP*T)-3'), Transcriptional regulator ERG 著者 Saxena, A.K, Gangwar, S.P. 登録日 2017-09-04 公開日 2018-11-14 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.769 Å) 主引用文献 Comparative structure analysis of the ETSi domain of ERG3 and its complex with the E74 promoter DNA sequence Acta Crystallogr F Struct Biol Commun, 74, 2018
6VGD	Crystal structure of the DNA binding domain (DBD) of human FLI1 and the complex of the DBD of human Runx2 with core binding factor beta (Cbfb), in complex with 16mer DNA CAGAGGATGTGGCTTC 分子名称: Core-binding factor subunit beta, DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), ... 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6VG2	Crystal structure of the DNA binding domain of human transcription factor FLI1 in complex with 16-mer DNA CAGAGGATGTGGCTTC 分子名称: DNA (5'-D(*GP*AP*AP*GP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*CP*TP*TP*C)-3'), Friend leukemia integration 1 transcription factor 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
6VG8	Crystal structure of the DNA binding domains of human FLI1 and Runx2 in complex with 16-mer DNA CAGAGGATGTGGCTTC 分子名称: DNA (5'-D(P*CP*AP*GP*AP*GP*GP*AP*TP*GP*TP*GP*GP*CP*TP*TP*C)-3'), DNA (5'-D(P*GP*AP*AP*GP*CP*CP*AP*CP*AP*TP*CP*CP*TP*CP*TP*G)-3'), Friend leukemia integration 1 transcription factor, ... 著者 Hou, C, Tsodikov, O.V. 登録日 2020-01-07 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.31 Å) 主引用文献 Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins. Structure, 29, 2021
4L11	Structure of the C-linker/CNBHD of agERG channels 分子名称: AGAP007709-PA 著者 Brelidze, T.I. 登録日 2013-06-01 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structure of the C-terminal region of an ERG channel and functional implications. Proc.Natl.Acad.Sci.USA, 110, 2013
1PX9	Solution structure of the native CnErg1 Ergtoxin, a highly specific inhibitor of HERG channel 分子名称: ergtoxin 著者 Frenal, K, Wecker, K, Gurrola, G.B, Possani, L.D, Wolff, N, Delepierre, M. 登録日 2003-07-03 公開日 2004-06-22 最終更新日 2022-03-02 実験手法 SOLUTION NMR 主引用文献 Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K+ channels. Proteins, 56, 2004
1J5J	Solution structure of HERG-specific scorpion toxin BeKm-1 分子名称: BeKm-1 toxin 著者 Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V. 登録日 2002-04-16 公開日 2002-11-20 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1. J.Biol.Chem., 277, 2002
1LGL	Solution structure of HERG-specific scorpion toxin BeKm-1 分子名称: BeKm-1 toxin 著者 Korolokova, Y.V, Bocharov, E.V, Angelo, K, Maslennikov, I.V, Grinenko, O.V, Lipkin, A.V, Nosireva, E.D, Pluzhnikov, K.A, Olesen, S.-P, Arseniev, A.S, Grishin, E.V. 登録日 2002-04-16 公開日 2002-11-20 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 New binding site on common molecular scaffold provides HERG channel specificity of scorpion toxin BeKm-1. J.Biol.Chem., 277, 2002
4HQA	Crystal structure of PAS domain from the human ERG (hERG) potassium channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Adaixo, R, Morais-Cabral, J.H, Harley, C.A. 登録日 2012-10-25 公開日 2013-03-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structural properties of PAS domains from the KCNH potassium channels Plos One, 8, 2013
1BYW	STRUCTURE OF THE N-TERMINAL DOMAIN OF THE HUMAN-ERG POTASSIUM CHANNEL 分子名称: PROTEIN (HUMAN ERG POTASSIUM CHANNEL) 著者 Cabral, J.H.M, Lee, A, Mackinnon, R. 登録日 1998-10-15 公開日 1998-12-16 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure and Functional Analysis of the Herg Potassium Channel N-Terminus: A Eukaryotic Pas Domain Cell(Cambridge,Mass.), 95, 1998
7DW5	Crystal structure of DUX4 HD1-HD2 domain complexed with ERG sites 分子名称: BROMIDE ION, DNA (5'-D(P*CP*GP*AP*CP*TP*TP*GP*AP*TP*GP*AP*GP*AP*TP*TP*AP*GP*AP*CP*TP*G)-3'), Double homeobox protein 4-like protein 2 著者 Zhang, H, Cheng, N, Li, Z, Zhang, W, Dong, X, Huang, J, Meng, G. 登録日 2021-01-15 公開日 2021-11-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.83 Å) 主引用文献 DNA crosslinking and recombination-activating genes 1/2 (RAG1/2) are required for oncogenic splicing in acute lymphoblastic leukemia. Cancer Commun (Lond), 41, 2021
1ZHZ	Structure of yeast oxysterol binding protein Osh4 in complex with ergosterol 分子名称: ERGOSTEROL, KES1 protein, LEAD (II) ION 著者 Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. 登録日 2005-04-26 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
6CAY	Crystal structure of the first StART-like domain of Ysp2p/Lam2p in its apo and ergosterol-bound state. 分子名称: ERGOSTEROL, Sterol-binding protein 著者 Horenkamp, F.A, Valverde, D.P, Reinisch, K.M. 登録日 2018-02-01 公開日 2018-02-28 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis for sterol transport by StART-like lipid transfer domains. EMBO J., 37, 2018
1BXM	ENGINEERED BETA-CRYPTOGEIN COMPLEXED WITH ERGOSTEROL 分子名称: BETA-CRYPTOGEIN, ERGOSTEROL 著者 Boissy, G, Brunie, S. 登録日 1998-10-05 公開日 1999-06-15 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The 2.1 A structure of an elicitin-ergosterol complex: a recent addition to the Sterol Carrier Protein family. Protein Sci., 8, 1999
5H2D	Crystal structure of Osh1 ORD domain in complex with ergosterol 分子名称: ERGOSTEROL, KLLA0C04147p, SULFATE ION 著者 Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S. 登録日 2016-10-14 公開日 2017-05-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction Structure, 25, 2017
5YS0	Crystal structure of the second StARkin domain of Lam2 in complex with ergosterol 分子名称: ERGOSTEROL, Membrane-anchored lipid-binding protein YSP2 著者 Tong, J, Im, Y.J. 登録日 2017-11-11 公開日 2018-01-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites Proc. Natl. Acad. Sci. U.S.A., 115, 2018
7PIN	Stacked compact Dunaliella PSII 分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, (1~{S})-3,5,5-trimethyl-4-[(1~{E},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E},17~{E})-3,7,12,16-tetramethyl-18-[(4~{S})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohex-3-en-1-ol, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate, ... 著者 Caspy, I, Fadeeva, M, Mazor, Y, Nelson, N. 登録日 2021-08-22 公開日 2022-08-17 最終更新日 2023-03-01 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of Dunaliella Photosystem II reveals conformational flexibility of stacked and unstacked supercomplexes. Elife, 12, 2023
5AFW	Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1, ... 著者 Metzger, E, Willmann, D, McMillan, J, Petroll, K, Metzger, P, Gerhardt, S, vonMaessenhausen, A, Schott, A.K, Espejo, A, Eberlin, A, Wohlwend, D, Schuele, K.M, Schleicher, M, Perner, S, Bedford, M.T, Dengjel, J, Flaig, R, Einsle, O, Schuele, R. 登録日 2015-01-26 公開日 2016-01-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Assembly of Methylated Kdm1A and Chd1 Drives Androgen Receptor-Dependent Transcription and Translocation. Nat.Struct.Mol.Biol., 23, 2016

 

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