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6LXW
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BU of 6lxw by Molmil
Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ...
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-12
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
6LX3
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BU of 6lx3 by Molmil
Cryo-EM structure of human secretory immunoglobulin A
Descriptor: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor
Authors:Wang, Y, Wang, G, Li, Y, Xiao, J.
Deposit date:2020-02-10
Release date:2020-05-27
Last modified:2020-07-22
Method:ELECTRON MICROSCOPY (3.15 Å)
Cite:Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
6UE8
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BU of 6ue8 by Molmil
Structure of tetrameric sIgA complex (Class 1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UE9
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BU of 6ue9 by Molmil
Structure of tetrameric sIgA complex (Class 2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UE7
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BU of 6ue7 by Molmil
Structure of dimeric sIgA complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure of the secretory immunoglobulin A core.
Science, 367, 2020
6UEA
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BU of 6uea by Molmil
Structure of pentameric sIgA complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
Deposit date:2019-09-20
Release date:2020-02-19
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the secretory immunoglobulin A core.
Science, 367, 2020
3CHN
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BU of 3chn by Molmil
Solution structure of human secretory IgA1
Descriptor: Ig alpha-1 chain C region, Immunoglobulin kappa light chain, Secretory component
Authors:Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J.
Deposit date:2008-03-10
Release date:2008-12-30
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.
Mucosal Immunol, 2, 2009
3CM9
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BU of 3cm9 by Molmil
Solution Structure of Human SIgA2
Descriptor: Immunoglobulin heavy chain, Immunoglobulin light chain, Secretory component
Authors:Bonner, A, Almogren, A, Furtado, P.B, Kerr, M.A, Perkins, S.J.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:The nonplanar secretory IgA2 and near planar secretory IgA1 solution structures rationalize their different mucosal immune responses.
J.Biol.Chem., 284, 2009
7K0C
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BU of 7k0c by Molmil
Structure of Secretory IgM Core
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, Immunoglobulin heavy constant mu, ...
Authors:Kumar, N, Arthur, C.P, Ciferri, C, Matsumoto, M.L.
Deposit date:2020-09-04
Release date:2021-01-20
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structure of the human secretory immunoglobulin M core.
Structure, 29, 2021
8SKV
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BU of 8skv by Molmil
Structure of human SIgA1 in complex with Streptococcus pyogenes protein M4 (Arp4)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgA receptor, ...
Authors:Liu, Q, Stadtmueller, B.M.
Deposit date:2023-04-20
Release date:2023-10-25
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
8SKU
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BU of 8sku by Molmil
Structure of human SIgA1 in complex with human CD89 (FcaR1)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Liu, Q, Stadtmueller, B.M.
Deposit date:2023-04-20
Release date:2023-10-25
Last modified:2023-11-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions.
Nat Commun, 14, 2023
7YSG
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BU of 7ysg by Molmil
Cryo-EM structure of human FcmR bound to sIgM
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ...
Authors:Li, Y, Shen, H, Xiao, J.
Deposit date:2022-08-12
Release date:2023-02-01
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
7YTD
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BU of 7ytd by Molmil
Cryo-EM structure of four human FcmR bound to IgM-Fc/J
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ...
Authors:Li, Y, Shen, H, Xiao, J.
Deposit date:2022-08-14
Release date:2023-02-01
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
7YTC
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BU of 7ytc by Molmil
Cryo-EM structure of human FcmR bound to IgM-Fc/J
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ...
Authors:Li, Y, Shen, H, Xiao, J.
Deposit date:2022-08-14
Release date:2023-02-01
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
8GZN
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BU of 8gzn by Molmil
IgM-var2CSA complex
Descriptor: Erythrocyte membrane protein 1, Immunoglobulin J chain, Immunoglobulin heavy constant mu
Authors:Akhouri, R.R, Goel, S, Skoglund, U.
Deposit date:2022-09-27
Release date:2023-10-25
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-electron microscopy of IgM-VAR2CSA complex reveals IgM inhibits binding of Plasmodium falciparum to Chondroitin Sulfate A.
Nat Commun, 14, 2023
2OCW
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BU of 2ocw by Molmil
Solution structure of human secretory component
Descriptor: Polymeric-immunoglobulin receptor
Authors:Bonner, A, Perrier, C, Corthesy, B, Perkins, S.J.
Deposit date:2006-12-21
Release date:2007-04-10
Last modified:2023-12-27
Method:SOLUTION SCATTERING
Cite:Solution structure of human secretory component and implications for biological function.
J.Biol.Chem., 282, 2007
8AE3
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BU of 8ae3 by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8AE0
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BU of 8ae0 by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (7.1 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8ADY
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BU of 8ady by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8ADZ
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BU of 8adz by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
8AE2
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BU of 8ae2 by Molmil
Cryo-EM structure of full-length human immunoglobulin M - F(ab')2 conformation 5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, IgM C2-domain from mouse, ...
Authors:Chen, Q, Rosenthal, P, Tolar, P.
Deposit date:2022-07-12
Release date:2022-10-26
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (8.5 Å)
Cite:Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer.
Nat Commun, 13, 2022
2QEJ
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BU of 2qej by Molmil
Crystal structure of a Staphylococcus aureus protein (SSL7) in complex with Fc of human IgA1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
Authors:Ramsland, P.A, Willoughby, N, Trist, H.M, Farrugia, W, Hogarth, P.M, Fraser, J.D, Wines, B.D.
Deposit date:2007-06-26
Release date:2007-09-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1
Proc.Natl.Acad.Sci.Usa, 104, 2007
6KXS
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BU of 6kxs by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the ectodomain of pIgR
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Li, Y, Wang, G, Xiao, J.
Deposit date:2019-09-12
Release date:2020-02-05
Last modified:2021-12-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural insights into immunoglobulin M.
Science, 367, 2020
7JG2
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BU of 7jg2 by Molmil
Secretory Immunoglobin A (SIgA)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Igh protein, ...
Authors:Kumar Bharathkar, S, Parker, B.P, Malyutin, A.G, Stadtmueller, B.M.
Deposit date:2020-07-18
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:The structures of Secretory and dimeric Immunoglobulin A.
Elife, 9, 2020
7Y09
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BU of 7y09 by Molmil
Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ...
Authors:Shen, H, Ji, C, Xiao, J.
Deposit date:2022-06-03
Release date:2023-03-29
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.71 Å)
Cite:Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023

 

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