PDB: 5594 resultsInfo pagesStatus searchChemie searchBIRD

---

7NFI	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L7Y. Descriptor: CC-Type2-(LaId)4-L7Y Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFO	A hexameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17C. Descriptor: CC-Type2-(LaId)4-I17C Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.37 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFJ	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-L28Y. Descriptor: CC-Type2-(LaId)4-L28Y Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.19 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFK	An octameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I24S. Descriptor: CC-Type2-(LaId)4-I24S, ISOPROPYL ALCOHOL Authors: Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7NFP	A heptameric barrel state of a de novo coiled-coil assembly: CC-Type2-(LaId)4-I17K Descriptor: CC-Type2-(LaId)4-I17K, GLYCEROL Authors: Burton, A.J, Rhys, G.G, Dawson, W.M, Brady, R.L, Woolfson, D.N. Deposit date: 2021-02-07 Release date: 2022-03-02 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.43 Å) Cite: Differential sensing with arrays of de novo designed peptide assemblies. Nat Commun, 14, 2023
7AH0	Crystal structure of the de novo designed two-heme binding protein, 4D2 Descriptor: 4D2, PROTOPORPHYRIN IX CONTAINING FE Authors: Hutchins, G.H, Parnell, A.E, Anderson, J.L.R. Deposit date: 2020-09-23 Release date: 2021-10-06 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (1.91 Å) Cite: An expandable, modular de novo protein platform for precision redox engineering. Proc.Natl.Acad.Sci.USA, 120, 2023
1IVL	THE DE NOVO DESIGN OF AN ANTIBODY COMBINING SITE: CRYSTALLOGRAPHIC ANALYSIS OF THE VL DOMAIN CONFIRMS THE STRUCTURAL MODEL Descriptor: IGG-KAPPA M29B FV (LIGHT CHAIN), ISOPROPYL ALCOHOL Authors: Essen, L.-O, Skerra, A. Deposit date: 1994-05-04 Release date: 1994-08-31 Last modified: 2014-02-05 Method: X-RAY DIFFRACTION (2.17 Å) Cite: The de novo design of an antibody combining site. Crystallographic analysis of the VL domain confirms the structural model. J.Mol.Biol., 238, 1994
3P6I	Crystal structure of Symfoil-4T Permutation #2: de novo designed beta-trefoil architecture with symmetric primary structure Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, de novo designed beta-trefoil architecture with symmetric primary structure Authors: Blaber, M, Lee, J. Deposit date: 2010-10-11 Release date: 2011-10-12 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (1.32 Å) Cite: Permutations study of de novo designed symmetric beta-trefoil architecture To be Published
8CCR	Crystal structure of the T19D mutant of the de novo diheme binding 4D2 Descriptor: (2S)-2-hydroxybutanedioic acid, 4D2 (mutant T19D), CHLORIDE ION, ... Authors: Barringer, R, Anderson, R. Deposit date: 2023-01-27 Release date: 2023-08-09 Method: X-RAY DIFFRACTION (2.1 Å) Cite: An expandable, modular de novo protein platform for precision redox engineering. Proc.Natl.Acad.Sci.USA, 120, 2023
3RA3	Crystal structure of a section of a de novo design gigaDalton protein fibre Descriptor: SODIUM ION, p1c, p2f Authors: Zaccai, N.R, Sharp, T.H, Bruning, M, Woolfson, D.N, Brady, R.L. Deposit date: 2011-03-27 Release date: 2012-08-08 Last modified: 2013-06-19 Method: X-RAY DIFFRACTION (2.31 Å) Cite: Cryo-transmission electron microscopy structure of a gigadalton peptide fiber of de novo design Proc.Natl.Acad.Sci.USA, 109, 2012
5TX8	Solution structure of the de novo mini protein gHH_44 Descriptor: HH2 Authors: Buchko, G.W, Bahl, C.D, Baker, D. Deposit date: 2016-11-15 Release date: 2017-09-27 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Cytosolic expression, solution structures, and molecular dynamics simulation of genetically encodable disulfide-rich de novo designed peptides. Protein Sci., 27, 2018
4DZN	A de novo designed Coiled Coil CC-pIL Descriptor: COILED-COIL PEPTIDE CC-PIL Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.59 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4DZM	A de novo designed Coiled Coil CC-Di Descriptor: COILED-COIL PEPTIDE CC-DI Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (1.94 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4DZK	A de novo designed Coiled Coil CC-Tri-N13 Descriptor: CHLORIDE ION, COILED-COIL PEPTIDE CC-TRI-N13 Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.79 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
4DZL	A de novo designed Coiled Coil CC-Tri Descriptor: COILED-COIL PEPTIDE CC-TRI Authors: Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. Deposit date: 2012-03-01 Release date: 2012-08-29 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.3 Å) Cite: A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology. ACS Synth Biol, 1, 2012
3B83	Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Descriptor: TEN-D3 Authors: Hu, X, Ke, H, Kuhlman, B. Deposit date: 2007-10-31 Release date: 2008-11-04 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Computer-Based Redesign of a beta Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo beta Sheet Design. Structure, 16, 2008
3UD6	Structural analyses of covalent enzyme-substrate analogue complexes reveal strengths and limitations of de novo enzyme design Descriptor: 1-(6-METHOXYNAPHTHALEN-2-YL)BUTANE-1,3-DIONE, RETRO-ALDOLASE, SULFATE ION Authors: Baker, D, Stoddard, B.L, Althoff, E.A, Wang, L, Jiang, L, Moody, J, Bolduc, J, Lassila, J, Hilvert, D. Deposit date: 2011-10-27 Release date: 2011-11-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.091 Å) Cite: Structural analyses of covalent enzyme-substrate analog complexes reveal strengths and limitations of de novo enzyme design. J.Mol.Biol., 415, 2012
6XXV	Crystal Structure of a computationally designed Immunogen S2_1.2 in complex with its elicited antibody C57 Descriptor: Antibody C57, Heavy Chain, Light Chain, ... Authors: Yang, C, Sesterhenn, F, Correia, B.E, Pojer, F. Deposit date: 2020-01-28 Release date: 2020-04-22 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.20116425 Å) Cite: De novo protein design enables the precise induction of RSV-neutralizing antibodies. Science, 368, 2020
8ETQ	Designed pentafoil knot protein folded into a trefoil knot Descriptor: k-cTRP5 Authors: Doyle, L.A, Kibler, R.D, Bradley, P, Stoddard, B.L. Deposit date: 2022-10-17 Release date: 2023-10-25 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (2.42 Å) Cite: De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
8EVM	De novo design of chlorophyll special pair containing protein assemblies Descriptor: Chlorophyll dimer protein designs, Special Pair 3 (SP3x) Authors: Bera, A.K, Ennist, N.M. Deposit date: 2022-10-20 Release date: 2024-05-15 Method: X-RAY DIFFRACTION (3.05 Å) Cite: De novo design of chlorophyll special pair proteins To Be Published
7SQ3	Designed trefoil knot protein, variant 1 Descriptor: CHLORIDE ION, Designed trefoil knot protein, variant 1, ... Authors: Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. Deposit date: 2021-11-04 Release date: 2022-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.453 Å) Cite: De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
7SQ4	Designed trefoil knot protein, variant 2 Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Designed trefoil knot protein, variant 2, ... Authors: Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. Deposit date: 2021-11-04 Release date: 2022-06-29 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.493 Å) Cite: De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
7SQ5	Designed trefoil knot protein, variant 3 Descriptor: Designed trefoil knot protein, variant 3, SODIUM ION Authors: Takushi, B, Doyle, L, Stoddard, B.L, Bradley, P. Deposit date: 2021-11-04 Release date: 2022-11-09 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.205 Å) Cite: De novo design of knotted tandem repeat proteins. Nat Commun, 14, 2023
8GL3	De novo design of monomeric helical bundles for pH-controlled membrane lysis Descriptor: pRLB-519 Authors: Goldbach, N, Bera, A.K, Baker, D, Kang, A. Deposit date: 2023-03-20 Release date: 2023-09-06 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (2.3 Å) Cite: De novo design of monomeric helical bundles for pH-controlled membrane lysis. Protein Sci., 32, 2023
8FLX	De novo designed homotrimer; the fusion product of BGL17 and DHR59 Descriptor: LK031 Authors: Kibler, R.D, Kennedy, M.A, Stoddard, B.L, Lee, S. Deposit date: 2022-12-22 Release date: 2023-06-28 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (4.5 Å) Cite: De novo designed homotrimer; the fusion product of BGL17 and DHR59 To Be Published

<234567891011121314151617>