6XXV

Crystal Structure of a computationally designed Immunogen S2_1.2 in complex with its elicited antibody C57

Summary for 6XXV

• Entry DOI: 10.2210/pdb6xxv/pdb
• Related: 6S3D 6XWI
• Descriptor: Antibody C57, Heavy Chain, Antibody C57, Light Chain, S2_1.2, ... (4 entities in total)
• Functional Keywords: epitope scaffold, de novo designed protein, immunogen, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 134010.13

Authors

Yang, C.,Sesterhenn, F.,Correia, B.E.,Pojer, F. (deposition date: 2020-01-28, release date: 2020-04-22, Last modification date: 2024-01-24)

• Primary citation: Sesterhenn, F.,Yang, C.,Bonet, J.,Cramer, J.T.,Wen, X.,Wang, Y.,Chiang, C.I.,Abriata, L.A.,Kucharska, I.,Castoro, G.,Vollers, S.S.,Galloux, M.,Dheilly, E.,Rosset, S.,Corthesy, P.,Georgeon, S.,Villard, M.,Richard, C.A.,Descamps, D.,Delgado, T.,Oricchio, E.,Rameix-Welti, M.A.,Mas, V.,Ervin, S.,Eleouet, J.F.,Riffault, S.,Bates, J.T.,Julien, J.P.,Li, Y.,Jardetzky, T.,Krey, T.,Correia, B.E.; De novo protein design enables the precise induction of RSV-neutralizing antibodies.; Science, 368:-, 2020; PubMed: 32409444; DOI: 10.1126/science.aay5051

Experimental method

X-RAY DIFFRACTION (2.20116418766 Å)