8CEE
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![BU of 8cee by Molmil](/molmil-images/mine/8cee) | Rnase R bound to a 30S degradation intermediate (State I - head-turning) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CDU
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![BU of 8cdu by Molmil](/molmil-images/mine/8cdu) | Rnase R bound to a 30S degradation intermediate (main state) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CED
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![BU of 8ced by Molmil](/molmil-images/mine/8ced) | Rnase R bound to a 30S degradation intermediate (State I - head-turning) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.15 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CEC
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![BU of 8cec by Molmil](/molmil-images/mine/8cec) | Rnase R bound to a 30S degradation intermediate (State I - head-turning) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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8CDV
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![BU of 8cdv by Molmil](/molmil-images/mine/8cdv) | Rnase R bound to a 30S degradation intermediate (state II) | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Paternoga, H, Dimitrova-Paternoga, L, Wilson, D.N. | Deposit date: | 2023-02-01 | Release date: | 2023-12-20 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.73 Å) | Cite: | Structural basis of ribosomal 30S subunit degradation by RNase R. Nature, 626, 2024
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4V4L
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![BU of 4v4l by Molmil](/molmil-images/mine/4v4l) | Structure of the Drosophila apoptosome | Descriptor: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apaf-1 related killer DARK, MAGNESIUM ION | Authors: | Yuan, S, Topf, M, Akey, C.W, Ludtke, S.J. | Deposit date: | 2010-10-04 | Release date: | 2014-07-09 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structure of the Drosophila apoptosome at 6.9 angstrom resolution Structure, 19, 2011
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7AV8
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![BU of 7av8 by Molmil](/molmil-images/mine/7av8) | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212 | Descriptor: | PH-interacting protein | Authors: | Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC) | Deposit date: | 2020-11-04 | Release date: | 2021-01-13 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212 To Be Published
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6LHW
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![BU of 6lhw by Molmil](/molmil-images/mine/6lhw) | Structure of N-terminal and C-terminal domains of FANCA | Descriptor: | Fanconi anemia complementation group A | Authors: | Jeong, E, Lee, S, Shin, J, Kim, Y, Kim, J, Scharer, O, Kim, Y, Kim, H, Cho, Y. | Deposit date: | 2019-12-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.84 Å) | Cite: | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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7KWO
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![BU of 7kwo by Molmil](/molmil-images/mine/7kwo) | rFVIIIFc-VWF-XTEN (BIVV001) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COPPER (II) ION, ... | Authors: | Fuller, J.R, Batchelor, J.D. | Deposit date: | 2020-12-01 | Release date: | 2021-03-03 | Last modified: | 2021-06-09 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular determinants of the factor VIII/von Willebrand factor complex revealed by BIVV001 cryo-electron microscopy. Blood, 137, 2021
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6LHV
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![BU of 6lhv by Molmil](/molmil-images/mine/6lhv) | Structure of FANCA and FANCG Complex | Descriptor: | Fanconi anemia complementation group A, Fanconi anemia complementation group G | Authors: | Jeong, E, Lee, S, Shin, J, Kim, Y, Scharer, O, Kim, Y, Kim, H, Cho, Y. | Deposit date: | 2019-12-10 | Release date: | 2020-03-25 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.59 Å) | Cite: | Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Res., 48, 2020
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6JCX
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![BU of 6jcx by Molmil](/molmil-images/mine/6jcx) | |
7KTR
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![BU of 7ktr by Molmil](/molmil-images/mine/7ktr) | Cryo-EM structure of the human SAGA coactivator complex (TRRAP, core) | Descriptor: | Ataxin-7, INOSITOL HEXAKISPHOSPHATE, Isoform 3 of Transcription factor SPT20 homolog, ... | Authors: | Herbst, D.A, Esbin, M.N, Nogales, E. | Deposit date: | 2020-11-24 | Release date: | 2021-11-10 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.93 Å) | Cite: | Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
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6JCY
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![BU of 6jcy by Molmil](/molmil-images/mine/6jcy) | |
6HLR
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![BU of 6hlr by Molmil](/molmil-images/mine/6hlr) | Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused) | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | Deposit date: | 2018-09-11 | Release date: | 2019-04-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
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7TLR
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![BU of 7tlr by Molmil](/molmil-images/mine/7tlr) | |
7TLM
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![BU of 7tlm by Molmil](/molmil-images/mine/7tlm) | Structure of Atopobium parvulum SufS | Descriptor: | Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Karunakaran, G, Couture, J.F. | Deposit date: | 2022-01-18 | Release date: | 2022-02-16 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease. Febs Lett., 596, 2022
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7TLQ
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![BU of 7tlq by Molmil](/molmil-images/mine/7tlq) | Structure of Atopobium parvulum SufS C375S | Descriptor: | Cysteine desulfurase, PYRIDOXAL-5'-PHOSPHATE | Authors: | Karunakaran, G, Couture, J.F. | Deposit date: | 2022-01-18 | Release date: | 2022-02-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of Atopobium parvulum SufS cysteine desulfurase linked to Crohn's disease. Febs Lett., 596, 2022
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7K66
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![BU of 7k66 by Molmil](/molmil-images/mine/7k66) | Structure of Blood Coagulation Factor VIII in Complex with an Anti-C1 Domain Pathogenic Antibody Inhibitor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2A9 heavy chain, ... | Authors: | Childers, K.C, Gish, J, Jarvis, L, Peters, S, Garrels, C, Smith, I.W, Spencer, H.T, Spiegel, P.C. | Deposit date: | 2020-09-18 | Release date: | 2020-10-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.92 Å) | Cite: | Structure of blood coagulation factor VIII in complex with an anti-C1 domain pathogenic antibody inhibitor. Blood, 137, 2021
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7KBT
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![BU of 7kbt by Molmil](/molmil-images/mine/7kbt) | Factor VIII in complex with the anti-C2 domain antibody, G99 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Ronayne, E.K, Gish, J, Wilson, C, Peters, S, Spencer, H.T, Spiegel, P.C, Childers, K.C. | Deposit date: | 2020-10-02 | Release date: | 2020-11-18 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (4.15 Å) | Cite: | Structure of Blood Coagulation Factor VIII in Complex With an Anti-C2 Domain Non-Classical, Pathogenic Antibody Inhibitor Front Immunol, 12, 2021
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7BBO
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![BU of 7bbo by Molmil](/molmil-images/mine/7bbo) | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P212121 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, PH-interacting protein | Authors: | Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC) | Deposit date: | 2020-12-18 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.32 Å) | Cite: | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group P21212 To Be Published
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7BBP
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![BU of 7bbp by Molmil](/molmil-images/mine/7bbp) | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with H4K5acK8ac | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Histone H4, ... | Authors: | Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F, Structural Genomics Consortium (SGC) | Deposit date: | 2020-12-18 | Release date: | 2021-03-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with H4K5acK8ac To Be Published
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6IPB
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![BU of 6ipb by Molmil](/molmil-images/mine/6ipb) | |
6MF2
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![BU of 6mf2 by Molmil](/molmil-images/mine/6mf2) | Improved Model of Human Coagulation Factor VIII | Descriptor: | CALCIUM ION, COPPER (I) ION, Coagulation factor VIII, ... | Authors: | Smith, I.W, Spiegel, P.C. | Deposit date: | 2018-09-08 | Release date: | 2019-09-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.609364 Å) | Cite: | The 3.2 angstrom structure of a bioengineered variant of blood coagulation factor VIII indicates two conformations of the C2 domain. J.Thromb.Haemost., 18, 2020
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7AV9
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![BU of 7av9 by Molmil](/molmil-images/mine/7av9) | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2 | Descriptor: | 1,2-ETHANEDIOL, PH-interacting protein | Authors: | Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F. | Deposit date: | 2020-11-04 | Release date: | 2021-01-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Crystal Structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in space group C2 To Be Published
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6HLS
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![BU of 6hls by Molmil](/molmil-images/mine/6hls) | Yeast apo RNA polymerase I* | Descriptor: | DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA135, DNA-directed RNA polymerase I subunit RPA14, ... | Authors: | Tafur, L, Sadian, Y, Weis, F, Muller, C.W. | Deposit date: | 2018-09-11 | Release date: | 2019-04-03 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2. Elife, 8, 2019
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