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2ICW
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Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Wang, L, Zhao, Y, Li, H.
Deposit date:2006-09-13
Release date:2007-03-20
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC.
Nat.Struct.Mol.Biol., 14, 2007
2IWG
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BU of 2iwg by Molmil
COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC
Descriptor: 52 KDA RO PROTEIN, IG GAMMA-1 CHAIN C, alpha-L-fucopyranose, ...
Authors:James, L.C, Keeble, A.H, Rhodes, D.A, Trowsdale, J.
Deposit date:2006-06-30
Release date:2007-03-27
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for Pryspry-Mediated Tripartite Motif (Trim) Protein Function.
Proc.Natl.Acad.Sci.USA, 104, 2007
2F53
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Directed Evolution of Human T-cell Receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without apparent cross-reactivity
Descriptor: Beta-2-microglobulin, Cancer/testis antigen 1B, GLYCEROL, ...
Authors:Rizkallah, P.J, Jakobsen, B.K, Dunn, S.M, Sami, M.
Deposit date:2005-11-25
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Protein Sci., 15, 2006
2F74
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Murine MHC class I H-2Db in complex with human b2-microglobulin and LCMV-derived immunodminant peptide gp33
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ...
Authors:Achour, A, Michaelsson, J, Harris, R.A, Ljunggren, H.G, Karre, K, Schneider, G, Sandalova, T.
Deposit date:2005-11-30
Release date:2006-02-14
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of the Differential Stability and Receptor Specificity of H-2D(b) in Complex with Murine versus Human beta(2)-Microglobulin.
J.Mol.Biol., 356, 2006
2HJL
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Crystal Structure of HLA-B5703 and HIV-1 peptide
Descriptor: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen B-57
Authors:Gillespie, G.M.A, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J.J, Plummer, F.A.
Deposit date:2006-06-30
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
2HJK
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Crystal Structure of HLA-B5703 and HIV-1 peptide
Descriptor: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen B-57
Authors:Gillespie, G.M.A, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J.J, Plummer, F.A.
Deposit date:2006-06-30
Release date:2006-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
2HG5
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Cs+ complex of a K channel with an amide to ester substitution in the selectivity filter
Descriptor: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, CESIUM ION, FAB HEAVY CHAIN, ...
Authors:Valiyaveetil, F.I, MacKinnon, R, Muir, T.W.
Deposit date:2006-06-26
Release date:2006-09-12
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
J.Am.Chem.Soc., 128, 2006
2IPK
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Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2
Descriptor: Enterotoxin type C-3, HA related Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine), ...
Authors:Nguyen, T.T, Stern, L.J.
Deposit date:2006-10-12
Release date:2007-03-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells.
Nat.Chem.Biol., 3, 2007
2J4W
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Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex
Descriptor: APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19
Authors:Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
Deposit date:2006-09-07
Release date:2007-01-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation.
J.Mol.Biol., 366, 2007
2FYY
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The role of T cell receptor alpha genes in directing human MHC restriction
Descriptor: 11-mer peptide from Epstein-Barr nuclear antigen 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Miles, J.J, Borg, N.A.
Deposit date:2006-02-08
Release date:2006-12-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.
J Immunol., 177, 2006
2FZ3
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The role of T cell receptor alpha genes in directing human MHC restriction
Descriptor: 11-mer peptide from Epstein-Barr nuclear antigen 1, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Miles, J.J, Borg, N.A.
Deposit date:2006-02-09
Release date:2006-12-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:TCR alpha genes direct MHC restriction in the potent human T cell response to a class I-bound viral epitope.
J Immunol., 177, 2006
2J5L
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Structure of a Plasmodium falciparum apical membrane antigen 1-Fab F8. 12.19 complex
Descriptor: APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19
Authors:Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A.
Deposit date:2006-09-18
Release date:2007-01-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation.
J.Mol.Biol., 366, 2007
2J8U
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Large CDR3a loop alteration as a function of MHC mutation.
Descriptor: AHIII TCR ALPHA CHAIN, AHIII TCR BETA CHAIN, Beta-2-microglobulin, ...
Authors:Miller, P.J, Benhar, Y.P, Biddison, W, Collins, E.J.
Deposit date:2006-10-27
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Single MHC mutation eliminates enthalpy associated with T cell receptor binding.
J. Mol. Biol., 373, 2007
2JCC
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BU of 2jcc by Molmil
AH3 recognition of mutant HLA-A2 W167A
Descriptor: BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, A-2 ALPHA CHAIN, ...
Authors:Miller, P, Benhar, Y.P, Biddison, W, Collins, E.J.
Deposit date:2006-12-21
Release date:2007-10-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Single Mhc Mutation Eliminates Enthalpy Associated with T Cell Receptor Binding.
J.Mol.Biol., 373, 2007
2FO4
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Enhanced MHC class I binding and immune responses through anchor modification of the non-canonical tumor associated MUC1-8 peptide
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 8-mer from Mucin-1, ...
Authors:Lazoura, E, Ramsland, P.A.
Deposit date:2006-01-12
Release date:2006-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide
Immunology, 119, 2006
2H2S
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BU of 2h2s by Molmil
Crystal Structure of E148A mutant of CLC-ec1 in SeCN-
Descriptor: CLC Cl transporter, FAB fragment, heavy chain, ...
Authors:Nguitragool, W, Miller, C.
Deposit date:2006-05-19
Release date:2006-05-30
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions
J.Mol.Biol., 362, 2006
2HTK
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BU of 2htk by Molmil
Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex
Descriptor: BROMIDE ION, Fab fragment, Heavy chain, ...
Authors:Accardi, A, Lobet, S, Williams, C, Miller, C, Dutzler, R.
Deposit date:2006-07-26
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Synergism between halide binding and proton transport in a CLC-type exchanger
J.Mol.Biol., 362, 2006
2I5Y
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Crystal structure of CD4M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 17B Heavy chain, Antibody 17B Light chain, ...
Authors:Huang, C.-C, Kwong, P.D.
Deposit date:2006-08-26
Release date:2006-10-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Combinatorial optimization of a CD4-mimetic miniprotein and cocrystal structures with HIV-1 gp120 envelope glycoprotein.
J.Mol.Biol., 382, 2008
2JIX
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BU of 2jix by Molmil
Crystal structure of ABT-007 FAB fragment with the soluble domain of EPO receptor
Descriptor: ABT-007 FAB FRAGMENT, ERYTHROPOIETIN RECEPTOR
Authors:Liu, Z, Stoll, V.S, DeVries, P, Jakob, C.G, Xie, N, Simmer, R.L, Lacy, S.E, Egan, D.A, Harlan, J.E, Lesniewski, R.R, Reilly, E.B.
Deposit date:2007-07-02
Release date:2007-07-10
Last modified:2020-03-18
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:A Potent Erythropoietin-Mimicking Human Antibody Interacts Through a Novel Binding Site.
Blood, 110, 2007
2GIT
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BU of 2git by Molmil
Human Class I MHC HLA-A2 in complex with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
Descriptor: Beta-2-microglobulin, FORMIC ACID, GLYCEROL, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-03-29
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
2GJ6
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BU of 2gj6 by Molmil
The complex between TCR A6 and human Class I MHC HLA-A2 with the modified HTLV-1 TAX (Y5K-4-[3-Indolyl]-butyric acid) peptide
Descriptor: 3-INDOLEBUTYRIC ACID, A6-Tcr, Beta-2-microglobulin, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-03-30
Release date:2006-10-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:T Cell Receptor Recognition via Cooperative Conformational Plasticity.
J.Mol.Biol., 363, 2006
2GJ7
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Crystal Structure of a gE-gI/Fc complex
Descriptor: Glycoprotein E, Ig gamma-1 chain C region, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Sprague, E.R, Wang, C, Baker, D, Bjorkman, P.J.
Deposit date:2006-03-30
Release date:2006-05-30
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (5 Å)
Cite:Crystal Structure of the HSV-1 Fc Receptor Bound to Fc Reveals a Mechanism for Antibody Bipolar Bridging.
Plos Biol., 4, 2006
2GUO
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Human Class I MHC HLA-A2 in complex with the native nonameric Melan-A/MART-1(27-35) peptide
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-05-01
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2GTZ
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Human Class I MHC HLA-A2 in complex with the nonameric Melan-A/MART-1(27-35) peptide having A28L substitution
Descriptor: Beta-2-microglobulin, GLYCEROL, HLA-A*0201 heavy chain, ...
Authors:Borbulevych, O.Y, Baker, B.M.
Deposit date:2006-04-28
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of MART-1(26/27-35) Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition
J.Mol.Biol., 372, 2007
2H2P
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Crystal structure of CLC-ec1 in complex with Fab fragment in SeCN-
Descriptor: CLC Cl transporter, FAB fragment, heavy chain, ...
Authors:Nguitragool, W, Miller, C.
Deposit date:2006-05-19
Release date:2006-05-30
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Uncoupling of a CLC Cl(-)/H(+) Exchange Transporter by Polyatomic Anions
J.Mol.Biol., 362, 2006

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