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3CBX
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The Dvl2 PDZ Domain in Complex with the C1 Inhibitory Peptide
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Dishevelled-2
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2008-02-23
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
3CBZ
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The Dvl2 PDZ Domain in Complex with the N2 Inhibitory Peptide
Descriptor: 1,2-ETHANEDIOL, Dishevelled-2, PHOSPHATE ION
Authors:Appleton, B.A, Wiesmann, C.
Deposit date:2008-02-23
Release date:2009-03-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Inhibition of Wnt signaling by Dishevelled PDZ peptides
Nat.Chem.Biol., 5, 2009
1IHJ
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Crystal Structure of the N-terminal PDZ domain of InaD in complex with a NorpA C-terminal peptide
Descriptor: InaD, phospholipase C
Authors:Kimple, M.E, Siderovski, D.P, Sondek, J.
Deposit date:2001-04-19
Release date:2001-08-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Functional relevance of the disulfide-linked complex of the N-terminal PDZ domain of InaD with NorpA.
EMBO J., 20, 2001
3B76
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Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase LNX, SODIUM ION
Authors:Ugochukwu, E, Burgess-Brown, N, Berridge, G, Elkins, J, Bunkoczi, G, Pike, A.C.W, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Gileadi, O, von Delft, F, Doyle, D, Structural Genomics Consortium (SGC)
Deposit date:2007-10-30
Release date:2007-11-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the third PDZ domain of human ligand-of-numb protein-X (LNX1) in complex with the C-terminal peptide from the coxsackievirus and adenovirus receptor.
To be Published
3CYY
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BU of 3cyy by Molmil
The crystal structure of ZO-1 PDZ2 in complex with the Cx43 peptide
Descriptor: Tight junction protein ZO-1, peptide from Gap junction alpha-1 protein
Authors:Pan, L, Zhang, M.
Deposit date:2008-04-27
Release date:2008-09-23
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
Embo J., 27, 2008
1M5Z
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The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area
Descriptor: AMPA receptor interacting protein
Authors:Feng, W, Fan, J, Jiang, M, Shi, Y, Zhang, M.
Deposit date:2002-07-11
Release date:2002-11-06
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The PDZ7 of Glutamate Receptor Interacting Protein Binds to its Target via a Novel Hydrophobic Surface Area
J.Biol.Chem., 277, 2002
3CH8
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The crystal structure of PDZ-Fibronectin fusion protein
Descriptor: C-terminal octapeptide from protein ARVCF, MAGNESIUM ION, fusion protein PDZ-Fibronectin,Fibronectin
Authors:Makabe, K, Huang, J, Koide, A, Koide, S.
Deposit date:2008-03-08
Release date:2009-03-31
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for exquisite specificity of affinity clamps, synthetic binding proteins generated through directed domain-interface evolution.
J.Mol.Biol., 392, 2009
1MFG
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The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
Descriptor: Erb-B2 INTERACTING PROTEIN, Erb-B2 carboxyl-terminal fragment
Authors:Birrane, G, Chung, J, Ladias, J.A.
Deposit date:2002-08-10
Release date:2003-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
1MFL
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The Structure of ERBIN PDZ domain bound to the Carboxy-terminal tail of the ErbB2 Receptor
Descriptor: Erb-B2 INTERACTING PROTEIN, PHOSPHORYLATED Erb-B2 carboxyl-terminal fragment.
Authors:Birrane, G, Chung, J, Ladias, J.A.
Deposit date:2002-08-12
Release date:2003-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Novel mode of ligand recognition by the erbin PDZ domain
J.Biol.Chem., 278, 2003
2RCZ
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BU of 2rcz by Molmil
Structure of the second PDZ domain of ZO-1
Descriptor: Tight junction protein ZO-1
Authors:Lavie, A, Lye, M.F.
Deposit date:2007-09-20
Release date:2007-10-09
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Domain swapping within PDZ2 is responsible for dimerization of ZO proteins.
J.Biol.Chem., 282, 2007
3ID4
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BU of 3id4 by Molmil
Crystal Structure of RseP PDZ2 domain fused GKASPV peptide
Descriptor: Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.604 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3ID2
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Crystal Structure of RseP PDZ2 domain
Descriptor: IODIDE ION, Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.089 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
3ID3
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Crystal Structure of RseP PDZ2 I304A domain
Descriptor: Regulator of sigma E protease
Authors:Li, X, Wang, B, Feng, L, Wang, J, Shi, Y.
Deposit date:2009-07-20
Release date:2009-08-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Cleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavage
Proc.Natl.Acad.Sci.USA, 106, 2009
2RRM
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Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1
Descriptor: Tight junction protein ZO-1
Authors:Hiroaki, H, Satomura, K, Goda, N, Umetsu, Y, Taniguchi, R, Ikegami, T, Furuse, M.
Deposit date:2011-01-06
Release date:2011-05-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1
Biomol.Nmr Assign., 5, 2011
3K82
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Crystal Structure of the third PDZ domain of PSD-95
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Disks large homolog 4, GLYCEROL, ...
Authors:Camara-Artigas, A, Gavira, J.A.
Deposit date:2009-10-13
Release date:2010-04-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Novel conformational aspects of the third PDZ domain of the neuronal post-synaptic density-95 protein revealed from two 1.4A X-ray structures
J.Struct.Biol., 170, 2010
2VWR
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Crystal structure of the second pdz domain of numb-binding protein 2
Descriptor: LIGAND OF NUMB PROTEIN X 2
Authors:Roos, A.K, Guo, K, Burgess-Brown, N, Yue, W.W, Elkins, J.M, Pike, A.C.W, Filippakopoulos, P, Arrowsmith, C.H, Wikstom, M, Edwards, A, von Delft, F, Bountra, C, Doyle, D, Oppermann, U.
Deposit date:2008-06-26
Release date:2008-09-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of the Second Pdz Domain of the Human Numb-Binding Protein 2
To be Published
2VZ5
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Structure of the PDZ domain of Tax1 (human T-cell leukemia virus type I) binding protein 3
Descriptor: CHLORIDE ION, IMIDAZOLE, TAX1-BINDING PROTEIN 3, ...
Authors:Murray, J.W, Shafqat, N, Yue, W, Pilka, E, Johannsson, C, Salah, E, Cooper, C, Elkins, J.M, Pike, A.C, Roos, A, Filippakopoulos, P, von Delft, F, Wickstroem, M, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Oppermann, U.
Deposit date:2008-07-30
Release date:2008-08-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.738 Å)
Cite:The Structure of the Pdz Domain of Tax1BP
To be Published
3JXT
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Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand
Descriptor: ACETATE ION, Disks large homolog 3, Voltage-dependent calcium channel gamma-2 subunit
Authors:Sainlos, M, Olivier, N.B, Imperiali, B.
Deposit date:2009-09-21
Release date:2010-09-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Caged mono- and divalent ligands for light-assisted disruption of PDZ domain-mediated interactions.
J.Am.Chem.Soc., 135, 2013
2X7Z
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Crystal Structure of the SAP97 PDZ2 I342W C378A mutant protein domain
Descriptor: AMMONIUM ION, DISKS LARGE HOMOLOG 1, IMIDAZOLE
Authors:Haq, S.R, Jurgens, M.C, Chi, C.N, Elfstrom, L, Koh, C.S, Selmer, M, Gianni, S, Jemth, P.
Deposit date:2010-03-04
Release date:2010-03-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Plastic Energy Landscape of Protein Folding: A Triangular Folding Mechanism with an Equilibrium Intermediate for a Small Protein Domain.
J.Biol.Chem., 285, 2010
2V90
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Crystal structure of the 3rd PDZ domain of intestine- and kidney- enriched PDZ domain IKEPP (PDZD3)
Descriptor: PDZ DOMAIN-CONTAINING PROTEIN 3, SULFATE ION
Authors:Uppenberg, J, Gileadi, C, Phillips, C, Elkins, J, Bunkoczi, G, Cooper, C, Pike, A.C.W, Salah, E, Ugochukwu, E, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Weigelt, J, Doyle, D.A.
Deposit date:2007-08-16
Release date:2007-08-28
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the 3Rd Pdz Domain of Intestine- and Kidney-Enriched Pdz Domain Ikepp (Pdzd3)
To be Published
2W4F
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BU of 2w4f by Molmil
CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN SCRIB1
Descriptor: 1,2-ETHANEDIOL, PROTEIN LAP4
Authors:Hozjan, V, Pilka, E.S, Roos, A.K, W Yue, W, Phillips, C, Bray, J, Cooper, C, Salah, E, Elkins, J.M, Muniz, J.R.C, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, von Delft, F, Bountra, C, Doyle, D.A, Oppermann, U.
Deposit date:2008-11-25
Release date:2008-12-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structure of the First Pdz Domain of Human Scrib1
To be Published
2WL7
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Crystal structure of the PSD93 PDZ1 domain
Descriptor: CHLORIDE ION, DISKS LARGE HOMOLOG 2, SULFATE ION
Authors:Fiorentini, M, Kallehauge, A, Kristensen, O, Kastrup, J.S, Gajhede, M.
Deposit date:2009-06-22
Release date:2010-01-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.028 Å)
Cite:Structure of the First Pdz Domain of Human Psd-93.
Acta Crystallogr.,Sect.F, 65, 2009
3HPK
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Oxidized dimeric PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
Descriptor: GLYCEROL, PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT
Authors:Yu, J, Shi, Y, Zhang, M.
Deposit date:2009-06-04
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain.
Biochemistry, 49, 2010
3KZE
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Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in Complex With SSRKEYYA Peptide
Descriptor: Synthetic Peptide, T-lymphoma invasion and metastasis-inducing protein 1
Authors:Shepherd, T.R, Fuentes, E.J.
Deposit date:2009-12-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion.
J.Mol.Biol., 398, 2010
3LNX
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Second PDZ domain from human PTP1E
Descriptor: IODIDE ION, THIOCYANATE ION, Tyrosine-protein phosphatase non-receptor type 13
Authors:Zhang, J, Chang, A, Ke, H, Phillips Jr, G.N, Lee, A.L, Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2010-02-03
Release date:2010-02-23
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.642 Å)
Cite:Crystallographic and nuclear magnetic resonance evaluation of the impact of peptide binding to the second PDZ domain of protein tyrosine phosphatase 1E.
Biochemistry, 49, 2010

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