3JXT

Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand

Summary for 3JXT

Entry DOI	10.2210/pdb3jxt/pdb
Descriptor	Disks large homolog 3, Voltage-dependent calcium channel gamma-2 subunit, ACETATE ION, ... (4 entities in total)
Functional Keywords	sap102, dlg3, stargazin, 4-dmap, 4db, pdz domain, solvatochromic flurophore, fluorogenic probe, calcium channel, calcium transport, ion transport, ionic channel, transport, voltage-gated channel, signaling protein
Biological source	Rattus norvegicus (rat) More
Cellular location	Membrane; Multi-pass membrane protein: O88602
Total number of polymer chains	4
Total formula weight	24095.75
Authors	Sainlos, M.,Olivier, N.B.,Imperiali, B. (deposition date: 2009-09-21, release date: 2010-09-29, Last modification date: 2023-11-22)
Primary citation	Sainlos, M.,Iskenderian-Epps, W.S.,Olivier, N.B.,Choquet, D.,Imperiali, B. Caged mono- and divalent ligands for light-assisted disruption of PDZ domain-mediated interactions. J.Am.Chem.Soc., 135:4580-4583, 2013 Cited by PubMed: 23480637 DOI: 10.1021/ja309870q PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation